Poly-Dex Side Effects

Generic name: dexamethasone / neomycin / polymyxin b ophthalmic

Note: This document contains side effect information about dexamethasone / neomycin / polymyxin b ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Poly-Dex.

Some side effects of Poly-Dex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to dexamethasone / neomycin / polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension

Serious side effects are not expected with this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dexamethasone / neomycin / polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension

Ocular

Ocular side effects associated with the corticosteroid component have included elevated intraocular pressure with possible development of glaucoma, optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. In addition, perforation of the cornea and sclera have occurred when administering topical steroids to patients with diseases that cause thinning of the cornea or sclera.

Corticosteroid containing preparations have also been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis.

Hypersensitivity

Hypersensitivity reactions have included allergic sensitization.

Local

Local reactions have included stinging or burning upon application.

Other

The development of a secondary infection has been reported in patients treated with antimicrobial and corticosteroid combinations. Fungal and viral infections of the cornea can develop with long-term application of corticosteroids.

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