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Mydriacyl Side Effects

Generic Name: tropicamide ophthalmic

Note: This page contains information about the side effects of tropicamide ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Mydriacyl.

For the Consumer

Applies to tropicamide ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by tropicamide ophthalmic (the active ingredient contained in Mydriacyl). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking tropicamide ophthalmic, check with your doctor or nurse as soon as possible:

Symptoms of too much medicine being absorbed into the body
  • Clumsiness or unsteadiness
  • confusion
  • fast heartbeat
  • flushing or redness of face
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increased thirst or dryness of mouth
  • skin rash
  • slurred speech
  • swollen stomach in infants
  • unusual behavior, especially in children
  • unusual drowsiness, tiredness, or weakness

Severity: Minor

Some of the side effects that can occur with tropicamide ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Blurred vision
  • headache
  • sensitivity of eyes to light
  • stinging of the eye when the medicine is applied

For Healthcare Professionals

Applies to tropicamide ophthalmic: compounding powder, ophthalmic solution


Ocular side effects associated with tropicamide ophthalmic (the active ingredient contained in Mydriacyl) have included transient stinging, blurry vision, photophobia, and superficial punctate keratitis. Increased intraocular pressure has been reported with mydriatic agents.[Ref]


Gastrointestinal side effects have included dry mouth, nausea, and vomiting.[Ref]

Nervous system

Nervous system side effects have included headaches, psychotic reactions, and behavioral disturbances.[Ref]


Cardiovascular side effects have included pallor, tachycardia, and vasomotor or cardiorespiratory collapse.[Ref]


Musculoskeletal side effects have included muscle rigidity.[Ref]


Hypersensitivity reactions (unspecified) have been reported.[Ref]


1. "Multum Information Services, Inc. Expert Review Panel"

2. "Product Information. Mydriacyl (tropicamide ophthalmic)." Allscripts Pharmaceutical Company, Vernon Hills, IL.

Not all side effects for Mydriacyl may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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