Mupirocin Side Effects

Brand Names: Bactroban, Centany

Please note - some side effects for Mupirocin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Mupirocin - for the Consumer

Mupirocin Cream

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Mupirocin Cream:

Burning; headache; nausea; stinging.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe irritation; severe itching.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: compounding powder; nasal ointment w/applicator; topical cream; topical kit; topical ointment

Local

Local adverse effects may be associated with mupirocin application. Mupirocin ointment or cream may commonly cause itching, pain, stinging, and burning. Local effects from the nasal formulation have included epistaxis, rhinitis, taste perversion, pharyngitis, burning, and cough.

Mupirocin ointment in a polyethylene glycol base has previously (prior to the release of a nasal formulation) been used intranasally. Common side effects associated with such use, which may be related to the polyethylene glycol, include nasal congestion, dryness, burning or irritation and unpleasant taste.

Gastrointestinal

Gastrointestinal side effects have included nausea (1.1%), abdominal pain (<1%), and diarrhea (<1%). Dry mouth has been reported with mupirocin nasal (<1%).

Hypersensitivity

Hypersensitivity reactions have infrequently included allergic contact dermatitis.

Nervous system

Nervous system side effects associated with intranasal mupirocin have included headache (9%). Dizziness has been reported with mupirocin ointment (<1%).

Ocular

Ocular side effects associated with mupirocin nasal ointment have included blepharitis (<1%).

Dermatologic

Dermatologic side effects associated with mupirocin ointment or cream have included pain and bleeding secondary to eczema, cellulitis, dermatitis, increased exudate, secondary wound infection, hives, and rash.

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