Mozobil Side Effects

Generic name: plerixafor

Note: This document contains side effect information about plerixafor. Some of the dosage forms listed on this page may not apply to the brand name Mozobil.

Some side effects of Mozobil may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to plerixafor: subcutaneous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking plerixafor (the active ingredient contained in Mozobil) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

• easy bruising or bleeding, unusual weakness;

• feeling like you might pass out; or

• pain in your upper stomach, spreading to your shoulder or back.

Less serious side effects of plerixafor may include:

• nausea, vomiting;

• diarrhea, constipation;

• dry mouth, numbness in or around your mouth;

• upset stomach, bloating, gas;

• tired feeling, trouble sleeping;

• headache, dizziness;

• joint or muscle pain;

• increased sweating; or

• itching, rash, or other irritation where the medication was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to plerixafor: subcutaneous solution

Gastrointestinal

Gastrointestinal side effects including diarrhea (37%), nausea (34%), vomiting (10%), flatulence (7%), abdominal pain, abdominal distention, dry mouth, stomach discomfort, oral hypoesthesia, constipation, and dyspepsia have been reported.

Local

Local side effects including injection site reactions (34%) have been reported. Mild to moderate injection site reactions at the site of subcutaneous administration of plerixafor (the active ingredient contained in Mozobil) have included erythema, hematoma, hemorrhage, induration, inflammation, irritation, pain, paresthesia, pruritus, rash, swelling, and urticaria.

General

General side effects including fatigue (27%) and malaise have been reported.

Nervous system

Nervous system side effects including headache (22%), dizziness (11%), and vasovagal reactions have been reported.

Musculoskeletal

Musculoskeletal side effects including arthralgia (13%) and musculoskeletal pain have been reported.

Psychiatric

Psychiatric side effects including insomnia (7%) have been reported.

Dermatologic

Dermatologic side effects including hyperhidrosis and erythema have been reported.

Respiratory

Respiratory side effects including a case of dyspnea and a case of hypoxia have been reported.

Ocular

Ocular side effects including periorbital swelling have been reported.

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