Methsuximide Side Effects

It is possible that some side effects of methsuximide may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to methsuximide: oral capsule

Along with its needed effects, methsuximide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking methsuximide:

Rare
  • Attempts at killing oneself
  • feeling that others are watching you or controlling your behavior
  • feeling that others can hear your thoughts
  • feeling, seeing, or hearing things that are not there
  • severe mood or mental changes
  • unusual behavior
Incidence not known
  • Attack, assault, or force
  • blistering, peeling, or loosening of the skin
  • blood in the urine
  • bloody, black, or tarry stools
  • chest pain
  • chills
  • cloudy urine
  • cough or hoarseness
  • diarrhea
  • discouragement
  • feeling sad or empty
  • fever
  • high fever
  • irritability
  • itching
  • joint or muscle pain
  • lack of appetite
  • loss of interest or pleasure
  • lower back or side pain
  • mood or mental changes
  • nervousness
  • painful or difficult urination
  • pale skin
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • shakiness and unsteady walk
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling around the eyes
  • swollen glands
  • tiredness
  • trouble with concentrating
  • trouble with sleeping
  • unexplained bleeding or bruising
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vision changes

Get emergency help immediately if any of the following symptoms of overdose occur while taking methsuximide:

Symptoms of overdose
  • Change in consciousness
  • difficult or troubled breathing
  • irregular, fast or slow, or shallow breathing
  • loss of consciousness
  • pale or blue lips, fingernails, or skin

Some side effects of methsuximide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Blurred vision
  • change in color vision
  • difficulty having a bowel movement (stool)
  • difficulty seeing at night
  • dizziness
  • drowsiness
  • heartburn
  • hiccups
  • hives or welts
  • increased sensitivity of the eyes to sunlight
  • loss of appetite
  • nausea or vomiting
  • pain or discomfort in the chest, upper stomach, or throat
  • redness of the skin
  • skin rash
  • sleeplessness
  • unable to sleep
  • weight loss

For Healthcare Professionals

Applies to methsuximide: oral capsule

Ocular

Ocular side effects have included periorbital edema.

Genitourinary

Genitourinary side effects have included proteinuria and microscopic hematuria.

Cardiovascular

Cardiovascular side effects have included hyperemia.

Dermatologic

Dermatologic side effects have included urticaria, Stevens-Johnson syndrome, and pruritic erythematous rashes.

Nervous system

Nervous system side effects have included drowsiness, ataxia or dizziness, irritability and nervousness, headache, blurred vision, photophobia, hiccups, and insomnia.

Psychiatric

Psychiatric side effects have included confusion, instability, mental slowness, depression, hypochondriacal behavior, and aggressiveness. There have also been rare reports of psychosis, suicidal behavior, and auditory hallucinations.

Hematologic

Hematologic side effects have included eosinophilia, leukopenia, monocytosis, and pancytopenia with or without bone marrow suppression.

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, anorexia, diarrhea, weight loss, epigastric and abdominal pain, and constipation.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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