Isopto Carbachol Side Effects

Generic Name: carbachol ophthalmic

Note: This page contains side effects data for the generic drug carbachol ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Isopto Carbachol.

It is possible that some side effects of Isopto Carbachol may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to carbachol ophthalmic: ophthalmic solution

Along with its needed effects, carbachol ophthalmic (the active ingredient contained in Isopto Carbachol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking carbachol ophthalmic:

  • Veil or curtain appearing across part of vision
Symptoms of too much medicine being absorbed into the body
  • Diarrhea, stomach cramps or pain, or vomiting
  • fainting
  • flushing or redness of face
  • frequent urge to urinate
  • increased sweating
  • irregular heartbeat
  • shortness of breath, wheezing, or tightness in chest
  • unusual tiredness or weakness
  • watering of mouth

Some side effects of carbachol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Blurred vision or change in near or distance vision
  • eye pain
  • stinging or burning of the eye
Less common
  • Headache
  • irritation or redness of eyes
  • twitching of eyelids

For Healthcare Professionals

Applies to carbachol ophthalmic: compounding powder, intraocular solution, ophthalmic solution


Cardiovascular side effects have included cardiac arrhythmia and hypotension.


Gastrointestinal side effects have included epigastric distress, abdominal cramps, diarrhea, and vomiting.


Ocular side effects of carbachol injection have included corneal clouding, persistent bullous keratopathy, retinal detachment, and postoperative iritis following cataract extraction. Ocular side effects of carbachol drops have included transient stringing and burning, irritation of the eyes, temporary decrease in visual acuity due to ciliary spasm, and transient ciliary and conjunctival injection.


Respiratory side effects have included exacerbation of bronchial asthma.

Nervous system

Nervous system side effects have included flushing, sweating, headache, syncope, and salivation.


Genitourinary side effects have included tightness in the urinary bladder and frequent urge to urinate.

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