Carbachol use while Breastfeeding

Drugs containing Carbachol: Miostat, Isopto Carbachol, Carboptic, Carbastat

Carbachol Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of carbachol ophthalmic drops during breastfeeding. Because of its short half-life, it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release,[1] and have variable effects on serum prolactin.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

References

1. Clarke G, Fall CH, Lincoln DW, Merrick LP. Effects of cholinoceptor antagonists on the suckling-induced and experimentally evoked release of oxytocin. Br J Pharmacol. 1978;63:519-27. PMID: 566601

2. Muller EE, Locatelli V, Cella S et al. Prolactin-lowering and -releasing drugs: mechanisms of action and therapeutic applications. Drugs. 1983;25:399-432. PMID: 6133737

Carbachol Identification

Substance Name

Carbachol

CAS Registry Number

51-83-2

Drug Class

Miotics

Muscarinic Agonists

Parasympathomimetics

Administrative Information

LactMed Record Number

754

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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