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Iopidine Side Effects

Generic name: apraclonidine ophthalmic

Medically reviewed by Drugs.com. Last updated on Jun 6, 2024.

Note: This document provides detailed information about Iopidine Side Effects associated with apraclonidine ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Iopidine.

Applies to apraclonidine ophthalmic: ophthalmic solution.

Serious side effects of Iopidine

Along with its needed effects, apraclonidine ophthalmic (the active ingredient contained in Iopidine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking apraclonidine ophthalmic:

For 0.5% apraclonidine

More common

  • allergic reaction (redness, itching, tearing of the eye)

Less common

  • blurred vision or change in vision
  • chest pain
  • clumsiness or unsteadiness
  • depression
  • dizziness
  • eye discharge, irritation, or pain
  • irregular heartbeat
  • numbness or tingling in the fingers or toes
  • raising of the upper eyelid
  • rash around the eyes
  • redness of the eyelid or inner lining of the eyelid
  • swelling of the eye, eyelid, or inner lining of the eyelid
  • swelling of the face, hands, or feet

For 1% apraclonidine

Less common

  • blurred vision
  • diarrhea
  • dry mouth
  • eye redness
  • fainting
  • feeling cold or sleepy
  • irregular heartbeat
  • lightheadedness
  • redness, swelling, or whitening of the eyelids
  • slow heartbeat
  • stomach pain
  • stuff or runny nose
  • swelling of the eyelid
  • trouble sleeping
  • unusual dreams
  • unusual taste in the mouth
  • vomiting
  • watering of eye

Get emergency help immediately if any of the following symptoms of overdose occur while taking apraclonidine ophthalmic:

For 1% apraclonidine

Symptoms of overdose

Other side effects of Iopidine

Some side effects of apraclonidine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For 0.5% apraclonidine

More common

  • dryness of the mouth
  • eye discomfort

Less common

  • change in taste or smell
  • constipation
  • crusting or scales on the eyelid or corner of the eye
  • discoloration of white part of the eye
  • drowsiness or sleepiness
  • dry nose or eyes
  • general feeling of discomfort or illness
  • headache
  • increased sensitivity of the eyes to light
  • muscle aches
  • nausea
  • nervousness
  • paleness of the eye or inner lining of the eyelid
  • runny nose
  • sore throat
  • tiredness or weakness
  • trouble in sleeping

For 1% apraclonidine

More common

  • increase in size of the pupil of the eye
  • paleness of the eye or inner lining of the eyelid

Less common

  • runny nose

For healthcare professionals

Applies to apraclonidine ophthalmic: ophthalmic solution.

General

The most commonly reported side effects were hyperemia, pruritus, discomfort, and tearing.[Ref]

Ocular

Gastrointestinal

Local

Respiratory

Nervous system

Cardiovascular

Bradycardia was reported in neonates and infants given after a single dose of the 1% ophthalmic solution.[Ref]

Dermatologic

Other

Lethargy was reported in neonates and infants given after a single dose of the 1% ophthalmic solution.[Ref]

Psychiatric

Musculoskeletal

Immunologic

Genitourinary

Hypersensitivity

Metabolic

Decreased oxygen saturation was reported in neonates and infants given after a single dose of the 1% ophthalmic solution.[Ref]

References

1. "Product Information. Iopidine (apraclonidine ophthalmic)." Alcon Laboratories Inc

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Iopidine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.