Evoxac Side Effects

Generic Name: cevimeline

Note: This document contains side effect information about cevimeline. Some of the dosage forms listed on this page may not apply to the brand name Evoxac.

Some side effects of Evoxac may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to cevimeline: oral capsule

Along with its needed effects, cevimeline (the active ingredient contained in Evoxac) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cevimeline:

Less common
  • Difficulty breathing
  • fast heartbeat
  • itching
Rare
  • Chest pain
  • fainting or light-headedness when getting up from a lying or a sitting position
  • swelling of gums or tongue
Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur while taking cevimeline:

  • Blurring or loss of vision
  • chest pain
  • cold, clammy skin
  • diarrhea, continuous and severe
  • disturbed color vision
  • dizziness, faintness, or light-headedness when getting up from a lying or sitting position
  • difficult or labored breathing
  • fast, pounding, slow, or irregular heartbeat
  • fast, weak pulse
  • headache
  • mental confusion
  • nausea
  • pounding in ears
  • shaking or trembling of hands or feet
  • shortness of breath
  • stomach cramps or pain
  • sweating
  • tearing of the eyes

Check with your doctor as soon as possible if any of the following side effects occur while taking cevimeline:

Less common
  • Bloody or cloudy urine
  • blurred vision
  • chest pain
  • cough
  • cracks in skin
  • difficult, burning , or painful urination
  • dizziness
  • dry or itching eyes
  • earache
  • feeling of constant movement of self or surroundings
  • itching of vagina, genital, or other skin area
  • lower back pain
  • redness or pain in eye
  • ringing or buzzing in the ears
  • scaling of skin
  • shortness of breath
  • skin rash
  • soreness or redness of skin
  • sores, ulcers, or white spots on tongue, lips, or inside of mouth
  • stiffness of muscles
  • swelling of hands, ankles, feet, or lower legs
  • swelling on side of face and jaw, with or without pain
  • tense muscles

Some side effects of cevimeline may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Excessive sweating
  • nausea
  • runny or stuffy nose
Less common
  • Abdominal pain
  • belching
  • bloating or swelling of face, hands, feet, or lower legs
  • bloody nose
  • bone or joint pain
  • burning, dry, or itching feeling in eye
  • change in vision
  • chills
  • constipation
  • cough, mucus-producing
  • decreased touch sensation
  • depression
  • diarrhea
  • dry mouth
  • eye pain
  • feelings of warmth in face, neck, arms, and occasionally, chest
  • fever
  • heartburn
  • hiccups
  • injury
  • itching
  • leg cramps
  • loss of appetite
  • migraine headache
  • mood or mental changes
  • muscle aches, pain, or stiffness
  • pain and swelling of eye, eyelid, or inner lining of eye
  • pain on side of face and jaw
  • pain, swelling, or redness of joints
  • postoperative pain
  • rapid weight gain
  • shortness of breath
  • skin disorder
  • tightness in chest
  • tooth disorders or pain
  • trembling or shaking of hands or feet
  • trouble in sleeping
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • watering of mouth
  • weight loss
Rare
  • Abnormal crying
  • deep, dark, purple bruise
  • swelling or puffiness of face
  • temperature sensation changes

For Healthcare Professionals

Applies to cevimeline: oral capsule

Nervous system

Nervous system side effects have included excess sweating (19%) and excessive salivation (2%).

Gastrointestinal

Gastrointestinal side effects have included nausea (14%), diarrhea (10%), dyspepsia (8%), abdominal pain (8%), vomiting (4.6%) and cholecystitis.

General

General side effects have included headache (14%), injury (5%), dizziness (4%), surgical intervention (3%), fatigue (3%), pain (3%), hot flushes (2%), and insomnia (2%).

Respiratory

Respiratory side effects have included sinusitis (12%), upper respiratory tract infection (11%), rhinitis (11%), coughing (6%), pharyngitis (5%), and bronchitis (4%).

Genitourinary

Genitourinary side effects have included urinary tract infection (6%) and urinary frequency (1%).

Musculoskeletal

Musculoskeletal side effects have included back pain (5%), arthralgia (4%), skeletal pain (3%), and rigors (1%).

Dermatologic

Dermatologic side effects have included rash (4%).

Ocular

Ocular side effects have included conjunctivitis (4%).

Hepatic

Hepatic side effects including liver and biliary systems disorders and cholecystitis have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web2)