Duac Side Effects
Generic name: benzoyl peroxide / clindamycin topical
Medically reviewed by Drugs.com. Last updated on Apr 21, 2024.
Note: This document provides detailed information about Duac Side Effects associated with benzoyl peroxide / clindamycin topical. Some dosage forms listed on this page may not apply specifically to the brand name Duac.
Applies to benzoyl peroxide/clindamycin topical: external gel, external kit.
Serious side effects of Duac
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad irritation where this drug is used.
Other side effects of Duac
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where this drug is used.
- Dry skin.
- Itching.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For healthcare professionals
Applies to benzoyl peroxide/clindamycin topical: topical gel, topical kit.
General
The most frequently reported side effects were erythema, scaling, peeling, dry skin, and itching.[Ref]
Dermatologic
- Very common (10% or more): Erythema (up to 28%), scaling (up to 19%), peeling (up to 17%), dry skin (up to 15%), itching (up to 15%)
- Common (1% to 10%): Pruritus, sunburn, burning, stinging
- Uncommon (0.1% to 1%): Contact dermatitis, rash, acne worsened
- Postmarketing reports: Urticaria[Ref]
Gastrointestinal
- Frequency not reported: Colitis
- Postmarketing reports: Pseudomembranous colitis, hemorrhagic diarrhea, diarrhea, abdominal pain[Ref]
Immunologic
- Postmarketing reports: Anaphylaxis, allergic reaction[Ref]
Local
- Common (1% to 10%): Application site reaction
- Uncommon (0.1% to 1%): Application site pain, application site exfoliation, application site irritation
- Postmarketing reports: Discoloration[Ref]
Nervous system
References
1. (2022) "Product Information. BenzaClin (benzoyl peroxide-clindamycin topical)." Apothecon Inc
2. (2018) "Product Information. Acanya (benzoyl peroxide-clindamycin topical)." Valeant Pharmaceuticals
3. (2018) "Product Information. Duac (benzoyl peroxide-clindamycin topical)." Stiefel Laboratories Inc
4. (2018) "Product Information. Onexton (benzoyl peroxide-clindamycin topical)." Valeant Pharmaceuticals
More about Duac (benzoyl peroxide / clindamycin topical)
- Check interactions
- Compare alternatives
- Reviews (278)
- Dosage information
- During pregnancy
- Generic availability
- Drug class: topical acne agents
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Further information
Duac side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.