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Cyklokapron Side Effects

Generic Name: tranexamic acid

Note: This page contains information about the side effects of tranexamic acid. Some of the dosage forms included on this document may not apply to the brand name Cyklokapron.

Not all side effects for Cyklokapron may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to tranexamic acid: oral syrup, oral tablet

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by tranexamic acid (the active ingredient contained in Cyklokapron). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking tranexamic acid:

More common
  • Pale skin
  • trouble breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
Incidence not known
  • Anxiety
  • change in vision
  • chest pain or tightness
  • confusion
  • cough
  • difficulty with swallowing
  • dizziness or lightheadedness
  • fainting
  • fast heartbeat
  • numbness of the hands
  • pain, redness, or swelling in the arm or leg
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • skin rash, hives, or itching

Some of the side effects that can occur with tranexamic acid may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Abdominal or stomach pain, discomfort, or tenderness
  • chills or fever
  • difficulty with moving
  • headache, severe and throbbing
  • joint or back pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • stuffy or runny nose
Incidence not known
  • Diarrhea
  • nausea
  • vomiting

For Healthcare Professionals

Applies to tranexamic acid: compounding powder, intravenous solution, oral tablet

Gastrointestinal

Gastrointestinal side effects have frequently included nausea, vomiting, and diarrhea. Abdominal pain has also been reported.

Nervous system

Nervous system side effects have included giddiness, dizziness, headache, tension headache, and migraine.

Hematologic

Hematologic side effects have included thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism, cerebral thrombosis, acute renal cortical necrosis, and central retinal artery and vein obstruction) and anemia.

Hypersensitivity

Hypersensitivity side effects have included allergic skin reactions, anaphylactic shock and anaphylactoid reactions.

A case of severe allergic reaction to tranexamic acid was reported involving a subject on her fourth cycle of treatment who experienced dyspnea, tightening of her throat, and facial flushing that required emergency medical treatment.

Ocular

Ocular side effects have rarely included disturbances of color vision and retinal artery occlusion.

Musculoskeletal

Musculoskeletal side effects have included back pain, musculoskeletal pain, muscle cramps and spasms, myalgia, and arthralgia including joint stiffness and swelling.

Respiratory

Respiratory side effects have included nasal and sinus symptoms including nasal, respiratory tract and sinus congestion, sinusitis, acute sinusitis, sinus headache, and allergic sinusitis and sinus pain.

Cardiovascular

Cardiovascular side effects have included hypotension when intravenous administration exceeded 1 mL per minute.

Genitourinary

Genitourinary side effects have included ureteral obstruction due to clot formation in patients with upper urinary tract bleeding.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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