Calcitriol topical Side Effects

Some side effects of calcitriol topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to calcitriol topical: topical ointment

Get emergency medical help if you have any of these signs of an allergic reaction while taking calcitriol topical: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using calcitriol topical and call your doctor at once if you have any of these serious side effects:

• blistering, or severe redness, itching, or other irritation of treated areas; or

• worsened symptoms or no improvement in psoriasis.

Using calcitriol topical can affect your body's ability to metabolize calcium. This can result in high levels of calcium in your blood (hypercalcemia). Symptoms of this condition include nausea, constipation, loss of appetite, increased thirst and urination, muscle weakness, confusion, and feeling tired or restless. Call your doctor if you have any of these symptoms.

Less serious side effects may include mild itching or skin discomfort.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to calcitriol topical: topical ointment

Metabolic

Metabolic side effects have included hypercalcemia which was reported in 24% of the subjects exposed to active drug and 16% of the subjects exposed to the vehicle.

In the subjects reported to have hypercalcemia, the elevations were less than 10% above the upper limit of normal.

Other

Other side effects have included laboratory test abnormality (8%).

Dermatologic

Dermatologic side effects have included psoriasis (4%), skin discomfort (3%), and pruritus (up to 3%). Acute blistering dermatitis, erythema, pruritus, skin discomfort, and skin burning sensation have been reported during postmarketing experience.

The drug was being used in the treatment of psoriasis.

Genitourinary

Genitourinary side effects have included urine abnormality (4%) and hypercalciuria (3%).

Renal

Kidney stones were reported in three subjects and confirmed in two.

Renal side effects have included kidney stones.

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