Beclomethasone nasal Side Effects

Some side effects of beclomethasone nasal may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to beclomethasone nasal: nasal aerosol liquid, nasal aerosol powder, nasal spray

Along with its needed effects, beclomethasone nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking beclomethasone nasal:

More common
  • Chills
  • dizziness
  • fast heartbeat
  • lightheadedness
  • rapid, shallow breathing
  • rash
  • unusual bleeding or bruising
Less common
  • change in vision
  • eye pain
  • headache
  • nausea or vomiting
  • tearing
  • unexplained nosebleeds
Incidence not known
  • Bloody mucus
  • cough or hoarseness
  • difficulty with breathing
  • dizziness
  • hives or welts
  • itching
  • loss of taste and smell
  • sores inside the nose

For Healthcare Professionals

Applies to beclomethasone nasal: nasal aerosol with adapter, nasal spray

General

Beclomethasone is generally well tolerated and, due to the nature of its administration, is not inclined to produce the systemic adverse effects generally associated with the use of corticosteroids.

Respiratory

One study suggests that dysphonia occurring in the absence of oral thrush may be due to a vocal cord abnormality attributable to inhaled steroid use. In some cases, dysphonia and vocal cord abnormalities persisted for months following discontinuation of beclomethasone.

Pulmonary eosinophilia, apparently associated with beclomethasone use, has been reported in at least two patients. Nasal candidiasis has been reported in a woman with undiagnosed chronic lymphocytic leukemia. Nasal perforation has been reported rarely.

Respiratory side effects including dysphonia and sore throat are commonly reported in patients receiving beclomethasone. This may or may not occur in the presence of oral thrush. Coughing and wheezing is frequently reported with inhaled beclomethasone use, especially in patients whose disease is under poor control. Nasal irritation and sneezing have been reported with intranasal administration.

Gastrointestinal

Gastrointestinal adverse effects due to beclomethasone are reported most commonly. Oropharyngeal candidiasis occurs in approximately 5% to 14% of patients treated with beclomethasone and occurs more often at higher dosages greater than 800 mcg per day. Candidiasis is generally limited to the oropharyngeal area.

Although candidiasis is generally limited to the oropharyngeal area, rare cases of esophageal candidiasis have been reported.

Nervous system

Nervous system side effects including headache have also been reported.

Endocrine

Endocrine abnormalities associated with beclomethasone rarely include suppression of the hypothalamic-pituitary-adrenal axis. The risk of adrenal suppression is less than that associated with systemic corticosteroids and occurs less frequently with daily doses of 2 mg per day or lower.

Immunologic

In a study of 548 asthmatic patients receiving beclomethasone, eight patients developed tuberculosis. Two patients who agreed to resume beclomethasone use following treatment experienced a reactivation of tuberculosis within 2 weeks.

In 1993, the American Academy of Allergy and Immunology (AAAI) requested that the FDA review its decision regarding the relabeling of inhaled corticosteroids following concerns about the risk of their use during severe viral infections. The AAAI's request was based on the lack of data linking inhaled corticosteroids to increases in complications of viral infections.

The danger of infections from immune suppression associated with inhaled corticosteroids has been debated. No conclusive evidence is available to support an increase in tuberculosis or viral infections in patients receiving inhaled beclomethasone.

Musculoskeletal

Long-term use of inhaled beclomethasone may be associated with a reduction in bone density. This effect may be dose-related and has been reported with high dosages (>=800 mcg/day for >= 1 year). Reduced levels of total body calcium have also been demonstrated in patients receiving lower dosages.

The reduction in bone density may be due to suppressed osteoblast function, as evidenced by decreased serum osteocalcin levels.

Ocular

Ocular adverse effects are more commonly seen with systemic administration of corticosteroids. However, posterior capsular cataracts have been occasionally reported with beclomethasone, especially with long-term use. In addition, prolonged use of high-dose inhaled corticosteroids ( >= 400 mcg of beclomethasone nasal) may be associated with increased risk of ocular hypertension and open angle glaucoma.

Dermatologic

Dermatologic adverse effects may include acne. Easy bruising has been associated with beclomethasone use in some patients.

Rosacea, presenting as new-onset facial eruptions, has been reported.

Psychiatric

Psychiatric adverse effects include rare cases of mania precipitated by beclomethasone.

Hypersensitivity

Hypersensitivity side effects have included rare cases of immediate and delayed anaphylactoid/anaphylactic reactions, urticaria, angioedema, rash, and bronchospasm.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Watch this video series to learn about managing severe allergies (anaphylaxis).

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