Apidra Side Effects
Please note - some side effects for Apidra may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
|
For the professional
|
For the professional
Apidra
Overall, clinical studies comparing Apidra with short-acting insulins did not demonstrate a difference in frequency of adverse events.
Adverse events commonly associated with human insulin therapy include the following:
Body as a whole: allergic reactions.
Skin and appendages: injection site reaction, lipodystrophy, pruritus, rash.
Other: hypoglycemia.
The rates and incidence of severe symptomatic hypoglycemia, defined as hypoglycemia requiring intervention from a third party, were comparable for all treatment regimens.
| Type 1 Diabetes – Mellitus Adult 12 weeks in combination with Lantus®* | Type 1 Diabetes Mellitus – Adult 26 weeks in combination with Lantus®† | Type 2 Diabetes Mellitus – Adult 26 weeks in combination with NPH human insulin† | |||||
|---|---|---|---|---|---|---|---|
| Apidra Pre-meal | Apidra Post-meal | Regular Human Insulin | Apidra | Humalog®‡ | Apidra | Regular Human Insulin | |
| Severe symptomatic hypoglycemia (events/month/patient) |
0.05 | 0.05 | 0.13 | 0.02 | 0.02 | 0.00 | 0.00 |
| Severe symptomatic hypoglycemia Percent of patients (n/total N) |
8.4% (24/286) |
8.4% (25/296) |
10.1% (28/278) |
4.8% (16/335) |
4.0% (13/326) |
1.4% (6/416) |
1.2% (5/420) |
Continuous Subcutaneous Insulin Infusion (CSII) (Type 1 Diabetes): The rates of catheter occlusions and infusion site reactions were similar for Apidra and Novolog®‡.
| Apidra | Novolog®‡ | |
|---|---|---|
| Catheter occlusions/month | 0.08 | 0.15 |
| Infusion site reactions | 10.3% (3/29) | 13.3% (4/30) |
More resources:
Apidra - Includes detailed dosage instructions.
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
