Amicar Side Effects

Generic Name: aminocaproic acid

Please note - some side effects for Amicar may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Amicar - for the Consumer

Amicar

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Amicar:

Confusion; decreased vision; diarrhea; dizziness; fatigue or tiredness; general body discomfort; headache; lightheadedness; muscle aches or swelling; nausea; pain; ringing in the ears; stomach pain; stuffy nose; swelling; vomiting; watery eyes.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); delirium; fainting; fever; hallucinations; muscle pain or weakness; seizures; slow heartbeat; sore throat; stroke; sudden change in the amount of urine you are producing; swelling of ankles, feet, or hands; unusual bleeding or bruising.

Amicar Syrup

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Amicar Syrup:

Confusion; decreased vision; diarrhea; dizziness; fatigue or tiredness; general body discomfort; headache; lightheadedness; muscle aches or swelling; nausea; pain; ringing in the ears; stomach pain; stuffy nose; swelling; vomiting; watery eyes.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); delirium; fainting; fever; hallucinations; muscle pain or weakness; seizures; slow heartbeat; sore throat; stroke; sudden change in the amount of urine you are producing; swelling of ankles, feet, or hands; unusual bleeding or bruising.

Amicar Side Effects - for the Professional

Amicar

Amicar is generally well tolerated. The following adverse experiences have been reported:

General: Edema, headache, malaise.

Hypersensitivity Reactions: Allergic and anaphylactoid reactions, anaphylaxis.

Cardiovascular: Bradycardia, hypotension, peripheral ischemia, thrombosis.

Gastrointestinal: Abdominal pain, diarrhea, nausea, vomiting.

Hematologic: Agranulocytosis, coagulation disorder, leukopenia, thrombocytopenia.

Musculoskeletal: CPK increased, muscle weakness, myalgia, myopathy, myositis, rhabdomyolysis.

Neurologic: Confusion, convulsions, delirium, dizziness, hallucinations, intracranial hypertension, stroke, syncope.

Respiratory: Dyspnea, nasal congestion, pulmonary embolism.

Skin: Pruritis, rash.

Special Senses: Tinnitus, vision decreased, watery eyes.

Urogenital: BUN increased, renal failure. There have been some reports of dry ejaculation during the period of Amicar treatment. These have been reported to date only in hemophilia patients who received the drug after undergoing dental surgical procedures. However, this symptom resolved in all patients within 24 to 48 hours of completion of therapy.

Side Effects by Body System

Hematologic

Hematologic side effects have included agranulocytosis, coagulation disorder, leukopenia, and thrombocytopenia.

Cardiovascular

Cardiovascular side effects have included bradycardia, hypotension, peripheral ischemia, and thrombosis.

Gastrointestinal

Gastrointestinal side effects have included abdominal pain, diarrhea, nausea, and vomiting.

Musculoskeletal

Musculoskeletal side effects have included increased levels of creatinine phosphokinase (CPK), muscle weakness, myalgia, myopathy, myositis, and rhabdomyolysis.

Nervous system

Nervous system side effects have included confusion, convulsions, delirium, dizziness, hallucinations, intracranial hypertension, stroke, and syncope.

Respiratory

Respiratory side effects have included dyspnea, nasal congestion, and pulmonary embolism.

Dermatologic

Dermatologic side effects have included pruritus and rash.

Renal

Renal side effects have included increased blood urea nitrogen (BUN) and renal failure.

Ocular

Ocular side effects have included decreased vision and watery eyes.

General

General side effects have included edema, headache, malaise, and tinnitus.

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis, and allergic and anaphylactoid reactions.

Local

Local side effects have included injection site reactions, pain, and necrosis.

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