Amicar Side Effects

Generic name: aminocaproic acid

Note: This document contains side effect information about aminocaproic acid. Some of the dosage forms listed on this page may not apply to the brand name Amicar.

Some side effects of Amicar may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to aminocaproic acid: intravenous solution, oral syrup, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking aminocaproic acid (the active ingredient contained in Amicar) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using aminocaproic acid and call your doctor at once if you have a serious side effect such as:

• sudden numbness or weakness, especially on one side of the body;

• sudden headache, confusion, problems with vision, speech, or balance;

• sudden cough, rapid breathing, fast heart rate;

• pain or swelling in one or both legs;

• muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine;

• urinating less than usual or not at all;

• drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;

• swelling, weight gain, feeling short of breath;

• slow heart rate, trouble breathing, feeling like you might pass out;

• numbness or tingling in your arms or legs;

• easy bruising or bleeding, purple or red pinpoint spots under your skin; or

• confusion, hallucinations;

Less serious side effects of aminocaproic acid may include:

• mild muscle pain or weakness;

• headache, tired feeling;

• nausea, vomiting, stomach pain, diarrhea;

• (in men) decreased amount of semen when having an orgasm;

• stuffy nose, watery eyes

• vision problems, ringing in your ears; or

• mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to aminocaproic acid: compounding powder, intravenous solution, oral syrup, oral tablet

Hematologic

Hematologic side effects have included agranulocytosis, coagulation disorder, leukopenia, and thrombocytopenia.

Cardiovascular

Cardiovascular side effects have included bradycardia, hypotension, peripheral ischemia, and thrombosis.

Gastrointestinal

Gastrointestinal side effects have included abdominal pain, diarrhea, nausea, and vomiting.

Musculoskeletal

Musculoskeletal side effects have included increased levels of creatinine phosphokinase (CPK), muscle weakness, myalgia, myopathy, myositis, and rhabdomyolysis.

Nervous system

Nervous system side effects have included confusion, convulsions, delirium, dizziness, hallucinations, intracranial hypertension, stroke, and syncope.

Respiratory

Respiratory side effects have included dyspnea, nasal congestion, and pulmonary embolism.

Dermatologic

Dermatologic side effects have included pruritus and rash.

Renal

Renal side effects have included increased blood urea nitrogen (BUN) and renal failure.

Ocular

Ocular side effects have included decreased vision and watery eyes.

General

General side effects have included edema, headache, malaise, and tinnitus.

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis, and allergic and anaphylactoid reactions.

Local

Local side effects have included injection site reactions, pain, and necrosis.

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