Alavert Side Effects

Generic Name: loratadine

Please note - some side effects for Alavert may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Alavert - for the Consumer

Alavert Allergy & Sinus 12-Hour Sustained-Release Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Alavert Allergy & Sinus 12-Hour Sustained-Release Tablets:

Coughing; dizziness; drowsiness; dry mouth; excitability; fatigue; headache; loss of appetite; mild stomach upset; nausea; nervousness; sleeplessness; sore throat; thirst.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty urinating; fast or irregular heartbeat; mental or mood changes; seizures; severe dizziness; uncontrolled shaking or tremor.

Alavert Syrup

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Alavert Syrup. Seek medical attention right away if any of these SEVERE side effects occur when using Alavert Syrup:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent dizziness.

Side Effects by Body System

Nervous system

Nervous system side effects have included headache in approximately 7% of treated patients. Usually, loratadine has not been shown to cause significant drowsiness, sedation, or impair psychomotor skills.

One study of second generation antihistamines reported cetirizine was 3.5 times more likely and acrivastine 2.8 times more likely to result in sedation than loratadine. There was no significant difference in incidence of sedation between loratadine and fexofenadine.

Cardiovascular

One study reported prolongation of the QT interval when larger than recommended (20 mg per day) doses of loratadine were administered with nefazodone (300 mg every 12 hours).

Cardiovascular side effects have included hypertension, hypotension, palpitation, supraventricular tachyarrhythmias, syncope and tachycardia.

Gastrointestinal

Gastrointestinal side effects have included rare reports of nausea and dry mouth.

Hepatic

Hepatic side effects have included rare reports of jaundice, hepatitis, and hepatic necrosis.

Two cases of necroinflammatory liver injury have been reported in patients taking loratadine. One case presented within 2 weeks of starting loratadine therapy and the other occurred 14 months after the start of therapy. Liver transplantation was necessary in one patient.

Dermatologic

Dermatologic side effects have included a case report of a fixed drug eruption.

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