Skip to Content

homatropine and hydrocodone

Generic Name: homatropine and hydrocodone (HOM a TROE peen and HYE dro KOE done)
Brand Name: Hydromet, Tussigon, Hycodan, Hydrotropine, Hydromide, Hydropane

What is homatropine and hydrocodone?

Hydrocodone is a narcotic cough medicine.

Homatropine is a drug that works against the narcotic to prevent an overdose of this medication.

Homatropine and hydrocodone is a combination medicine used to treat cough.

Homatropine and hydrocodone may also be used for purposes not listed in this medication guide.

What is the most important information I should know about homatropine and hydrocodone?

Hydrocodone can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Hydrocodone may be habit-forming, even at regular doses. Never share homatropine and hydrocodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

What should I discuss with my health care provider before taking homatropine and hydrocodone?

You should not use this medicine if you are allergic to homatropine or hydrocodone.

Some medicines can interact with hydrocodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure homatropine and hydrocodone is safe for you, tell your doctor if you have:

  • severe asthma or breathing problems;

  • a history of head injury, brain tumor, or seizures;

  • liver or kidney disease;

  • Addison's disease;

  • underactive thyroid;

  • enlarged prostate or urination problems;

  • glaucoma; or

  • stomach problems.

It is not known whether this medicine will harm an unborn baby. If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether homatropine and hydrocodone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Homatropine and hydrocodone is not approved for use by anyone younger than 6 years old.

How should I take homatropine and hydrocodone?

Follow all directions on your prescription label. Hydrocodone can slow or stop your breathing. Never use homatropine and hydrocodone in larger amounts, or for longer than prescribed.

Homatropine and hydrocodone may be habit-forming. Never share homatropine and hydrocodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using homatropine and hydrocodone.

Store at room temperature away from heat, moisture, and light.

Keep track of the amount of medicine used from each new bottle. Homatropine and hydrocodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A hydrocodone overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pale skin, blue-colored lips, and fainting.

What should I avoid while taking homatropine and hydrocodone?

Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with hydrocodone. Check your food and medicine labels to be sure these products do not contain alcohol.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how homatropine and hydrocodone will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Homatropine and hydrocodone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using homatropine and hydrocodone and call your doctor at once if you have:

  • weak or shallow breathing;

  • severe drowsiness;

  • painful or difficult urination;

  • infertility, missed menstrual periods;

  • impotence, sexual problems, loss of interest in sex;

  • confusion, fear, paranoia, unusual thoughts or behavior;

  • a light-headed feeling, like you might pass out; or

  • low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Homatropine and hydrocodone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

Common side effects may include:

  • drowsiness, dizziness;

  • constipation, nausea, vomiting;

  • itching, rash; or

  • trouble concentrating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Homatropine and hydrocodone dosing information

Usual Adult Dose for Cough:

5 mL of syrup (1.5 mg-5 mg/5 mL) or I tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 6 doses (6 tablets or 30 mL) in 24 hours.

Usual Pediatric Dose for Cough:

6 years to 12 years:

2.5 mL of syrup (1.5 mg-5 mg/5 mL) or one-half tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 3 tablets or 15 mL in 24 hours.

> 12 years:

5 mL of syrup (1.5 mg-5 mg/5 mL) or I tablet (1.5 mg-5 mg) orally every 4 to 6 hours as needed. Do not exceed 6 doses (6 tablets or 30 mL) in 24 hours.

What other drugs will affect homatropine and hydrocodone?

Some medicines can cause unwanted or dangerous effects when used with homatropine and hydrocodone. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking homatropine and hydrocodone with a sleeping pill, muscle relaxer, other pain medicine, or medicine for anxiety, depression, or seizures.

Other drugs may interact with homatropine and hydrocodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your pharmacist can provide more information about homatropine and hydrocodone.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02. Revision Date: 2016-04-06, 9:59:51 AM.

Hide