TNKase and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with TNKase (tenecteplase).
High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
tenecteplase -bleeding
The most common complication encountered during tenecteplase therapy is bleeding. Tenecteplase therapy in patients with acute myocardial infarction is contraindicated in patients with active internal bleeding, history of cerebrovascular accident, intracranial or intraspinal surgery or trauma within 2 months, intracranial neoplasms, arteriovenous malformations or aneurysm, bleeding diathesis or severe uncontrolled hypertension, due to an increased risk of bleeding. Each patient being considered for therapy should be carefully evaluated and anticipated benefits weighed against potential risks associated with therapy.
References
- "Product Information. TNKase (tenecteplase)." Genentech PROD (2001):
TNKase drug interactions
There are 151 drug interactions with TNKase (tenecteplase).
TNKase disease interactions
There are 2 disease interactions with TNKase (tenecteplase) which include:
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- Drug class: thrombolytics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
