Alcohol, Food & Lifestyle Interactions

Nexavar (sorafenib) Alcohol, Food & Lifestyle Interactions

There is 1 food and lifestyle interaction with Nexavar (sorafenib):

Moderate Food Interaction

 

ADJUST DOSING INTERVAL: Food may reduce the oral absorption and bioavailability of sorafenib. According to the product labeling, sorafenib bioavailability was reduced by 29% when administered with a high-fat meal compared to administration in the fasted state. When given with a moderate-fat meal, bioavailability was similar to that in the fasted state.

MANAGEMENT: To ensure maximal and consistent oral absorption, sorafenib should be taken at least one hour before or two hours after eating.

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Nexavar (sorafenib) drug Interactions

There are 81 drug interactions with Nexavar (sorafenib)

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