Latuda (lurasidone) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Latuda (lurasidone) which include:
Using lurasidone together with ethanol can increase nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with lurasidone. Do not use more than the recommended dose of lurasidone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Consumer information for this interaction is not currently available.
GENERALLY AVOID: The consumption of grapefruit juice may theoretically increase the serum concentrations and pharmacological effects of lurasidone. The mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. The clinical significance is unknown. The consumption of alcoholic beverages may potentiate some side effects of lurasidone.
MANAGEMENT: According to the manufacturer, consumption of grapefruit juice, grapefruit extract, and alcohol should be avoided during lurasidone therapy.
- Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Latuda (lurasidone)." Sunovion Pharmaceuticals Inc, Marlborough, MA.
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Latuda (lurasidone) drug Interactions
There are 863 drug interactions with Latuda (lurasidone)
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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