Alcohol, Food & Lifestyle Interactions

Norvasc (amlodipine) Alcohol, Food & Lifestyle Interactions

There are 2 food and lifestyle interactions with Norvasc (amlodipine) which include:

Norvasc and multivitamins with minerals

Moderate Drug Interaction

MONITOR: Calcium-containing products may decrease the effectiveness of calcium channel blockers by saturating calcium channels with calcium. Calcium chloride has been used to manage acute severe verapamil toxicity.

MANAGEMENT: Management consists of monitoring the effectiveness of calcium channel blocker therapy during coadministration with calcium products.

Minor Food Interaction

 

The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. The mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. Data have been conflicting and the clinical significance is unknown. Monitoring for calcium channel blocker adverse effects (e.g., headache, hypotension, syncope, tachycardia, edema) is recommended.

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Norvasc (amlodipine) drug Interactions

There are 417 drug interactions with Norvasc (amlodipine)

Norvasc (amlodipine) disease Interactions

There are 4 disease interactions with Norvasc (amlodipine) which include:

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