Amlodipine use while Breastfeeding

Drugs containing Amlodipine: Norvasc, Lotrel, Azor, Exforge, Caduet, Tribenzor, Exforge HCT, Tekamlo, Twynsta, Amturnide, Show all 11 »Amlobenz

Amlodipine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because no information is available on the use of amlodipine during breastfeeding, an alternate drug may be preferred.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

A woman took amlodipine for hypertension 5 mg daily beginning 2 weeks postpartum. Her exclusively breastfed infant was examined regularly and at 3 months of age was healthy and had normal physical and neurological development.[1]

One woman received amlodipine 2.5 mg orally twice daily during pregnancy for hypertension associated with glomerulonephritis. The dose was increased to 5 mg twice daily on day 2 postpartum. Her exclusively breastfed infant's growth was normal throughout the first year of life and no adverse effects were noted.[2]

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Nifedipine, Nitrendipine

References

1. Ahn HK, Nava-Ocampo AA, Han JY et al. Exposure to amlodipine in the first trimester of pregnancy and during breastfeeding. Hypertens Pregnancy. 2007;26:179-87. PMID: 17469008

2. Szucs KA, Axline SE, Rosenman MB. Maternal membranous glomerulonephritis and successful exclusive breastfeeding. Breastfeed Med. 2010;5:123-6. PMID: 20491564

Amlodipine Identification

Substance Name

Amlodipine

CAS Registry Number

88150-42-9

Drug Class

  • Antihypertensive Agents
  • Calcium Channel Blockers
  • Vasodilator Agents

Administrative Information

LactMed Record Number

11

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2010-06-02

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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