Xeljanz Drug Interactions
Currently displaying 369 drugs known to have a major interaction with Xeljanz (tofacitinib).
- 369 major drug interactions
- 258 moderate drug interactions
- 8 minor drug interactions
Major interactions with Xeljanz (tofacitinib)
Note: Showing generic names only.
A
- abatacept
- abemaciclib
- abrocitinib
- acalabrutinib
- adalimumab
- aldesleukin
- alefacept
- alemtuzumab
- allogeneic processed thymus tissue
- altretamine
- amprenavir
- anakinra
- anifrolumab
- anti-thymocyte globulin (rabbit)
- apalutamide
- asciminib
- asparaginase escherichia coli
- atazanavir
- atezolizumab
- avacopan
- avapritinib
- axicabtagene ciloleucel
- azacitidine
- azathioprine
B
- baricitinib
- basiliximab
- bcg
- bcg vaccine
- belantamab mafodotin
- belatacept
- belimumab
- belinostat
- bendamustine
- benralizumab
- betamethasone
- bexarotene
- bimekizumab
- bleomycin
- blinatumomab
- boceprevir
- bortezomib
- bosutinib
- brentuximab
- brexucabtagene autoleucel
- brigatinib
- brodalumab
- budesonide
- busulfan
C
- cabazitaxel
- canakinumab
- capecitabine
- carbamazepine
- carboplatin
- carfilzomib
- carmustine
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chlorambucil
- chloramphenicol
- chlorotrianisene
- cholera vaccine, live
- ciltacabtagene autoleucel
- cisplatin
- cladribine
- clarithromycin
- clofarabine
- clomiphene
- clozapine
- cobicistat
- cobimetinib
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- crovalimab
- cyclophosphamide
- cyclosporine
- cytarabine
D
- dacarbazine
- daclizumab
- dactinomycin
- danicopan
- daratumumab
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferiprone
- deflazacort
- delavirdine
- dengue vaccine
- denileukin diftitox
- deucravacitinib
- dexamethasone
- dienestrol topical
- diethylstilbestrol
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- docetaxel
- doxorubicin
- doxorubicin liposomal
- drospirenone
- dupilumab
- durvalumab
- duvelisib
E
- eculizumab
- efalizumab
- efgartigimod alfa
- eflornithine
- elotuzumab
- elranatamab
- encorafenib
- enfortumab vedotin
- enzalutamide
- epcoritamab
- epirubicin
- eribulin
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- etanercept
- ethinyl estradiol
- etonogestrel
- etoposide
- etrasimod
- everolimus
F
- fam-trastuzumab deruxtecan
- fexinidazole
- fingolimod
- floxuridine
- fluconazole
- fludarabine
- fludrocortisone
- fluorouracil
- fosamprenavir
- fosphenytoin
- fruquintinib
G
H
I
- ibritumomab
- ibrutinib
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- imatinib
- imetelstat
- indinavir
- inebilizumab
- infliximab
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, live
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon gamma-1b
- iobenguane I 131
- iodine i 131 tositumomab
- iptacopan
- irinotecan
- irinotecan liposomal
- isatuximab
- itraconazole
- ixabepilone
- ixazomib
- ixekizumab
K
L
- leflunomide
- lenalidomide
- levamisole
- levoketoconazole
- levonorgestrel
- lifileucel
- linezolid
- lisocabtagene maraleucel
- lomustine
- lonafarnib
- loncastuximab tesirine
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lymphocyte immune globulin, anti-thy (equine)
M
- measles virus vaccine
- mechlorethamine
- medroxyprogesterone
- megestrol
- melphalan
- melphalan flufenamide
- mepolizumab
- mercaptopurine
- methotrexate
- methylprednisolone
- midostaurin
- mirikizumab
- mitomycin
- mitotane
- mitoxantrone
- mogamulizumab
- momelotinib
- monomethyl fumarate
- mosunetuzumab
- mumps virus vaccine
- muromonab-cd3
- mycophenolate mofetil
- mycophenolic acid
N
- nadofaragene firadenovec
- natalizumab
- naxitamab
- nefazodone
- nelarabine
- nelfinavir
- nilotinib
- niraparib
- norethindrone
- norgestrel
O
- obinutuzumab
- ocrelizumab
- ofatumumab
- olaparib
- olaratumab
- omacetaxine
- osimertinib
- ospemifene
- oxaliplatin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- panobinostat
- pazopanib
- pegaspargase
- pegcetacoplan
- peginterferon alfa-2a
- peginterferon alfa-2b
- pemetrexed
- pentostatin
- phenobarbital
- phenytoin
- pirtobrutinib
- plicamycin
- polatuzumab vedotin
- poliovirus vaccine, live, trivalent
- pomalidomide
- ponatinib
- ponesimod
- posaconazole
- pozelimab
- pralatrexate
- prednisolone
- prednisone
- primidone
- procarbazine
- progesterone
- progesterone topical
- promazine
Q
R
- radium 223 dichloride
- raloxifene
- ravulizumab
- reslizumab
- ribociclib
- rifampin
- rifapentine
- rilonacept
- risankizumab
- ritlecitinib
- ritonavir
- rituximab
- romidepsin
- ropeginterferon alfa-2b
- rotavirus vaccine
- rozanolixizumab
- rubella virus vaccine
- rucaparib
- ruxolitinib
S
- sacituzumab govitecan
- samarium sm 153 lexidronam
- saquinavir
- sarilumab
- satralizumab
- secukinumab
- selinexor
- siltuximab
- siponimod
- sirolimus
- sirolimus protein-bound
- smallpox vaccine
- spesolimab
- st. john's wort
- streptozocin
- strontium-89 chloride
- sutimlimab
T
- tacrolimus
- tafasitamab
- talazoparib
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tarlatamab
- tazemetostat
- teclistamab
- telaprevir
- telithromycin
- temozolomide
- temsirolimus
- teniposide
- teplizumab
- teriflunomide
- thalidomide
- thioguanine
- thiotepa
- tildrakizumab
- tisagenlecleucel
- tisotumab vedotin
- tocilizumab
- topotecan
- toremifene
- tositumomab
- trabectedin
- tralokinumab
- trastuzumab
- triamcinolone
- triamcinolone ophthalmic
- trimetrexate
- troleandomycin
- tucatinib
- typhoid vaccine, live
U
V
- vamorolone
- varicella virus vaccine
- vedolizumab
- venetoclax
- vilobelimab
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- voriconazole
Y
Z
Xeljanz alcohol/food interactions
There is 1 alcohol/food interaction with Xeljanz (tofacitinib).
Xeljanz disease interactions
There are 13 disease interactions with Xeljanz (tofacitinib) which include:
- cardiovascular risk
- malignancy
- thrombosis
- infections
- tuberculosis
- viral reactivation
- cytopenias
- diabetes
- GI obstruction
- GI perforation
- hepatic disorder
- hyperlipidemia
- renal disease
More about Xeljanz (tofacitinib)
- Xeljanz consumer information
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- Reviews (138)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: antirheumatics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.