Tapentadol Drug Interactions
Currently displaying 186 drugs known to have a major interaction with tapentadol.
- 186 major drug interactions
- 193 moderate drug interactions
- 1 minor drug interaction
Major interactions with tapentadol
Note: Showing generic names only.
5
A
- acetylcarbromal
- alfentanil
- almotriptan
- alprazolam
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- aripiprazole
- asenapine
B
- baclofen
- benzphetamine
- brexanolone
- brexpiprazole
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cannabis
- cariprazine
- carisoprodol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpromazine
- chlorzoxazone
- citalopram
- clobazam
- clomipramine
- clonazepam
- clorazepate
- clozapine
- codeine
- cyclobenzaprine
D
- dantrolene
- daridorexant
- desipramine
- desvenlafaxine
- dexfenfluramine
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- diethylpropion
- dihydroergotamine
- dolasetron
- doxepin
- doxepin topical
- duloxetine
E
F
G
H
I
L
- lasmiditan
- lemborexant
- levomethadyl acetate
- levomilnacipran
- levorphanol
- linezolid
- lisdexamfetamine
- lithium
- lorazepam
- lorcaserin
- loxapine
- lumateperone
- lurasidone
M
- ma huang
- mazindol
- meperidine
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methocarbamol
- methylene blue
- metrizamide
- milnacipran
- mirtazapine
- molindone
- morphine
- morphine liposomal
N
O
P
- paliperidone
- palonosetron
- paraldehyde
- paroxetine
- pentazocine
- pentobarbital
- perphenazine
- phendimetrazine
- phenelzine
- phenobarbital
- phentermine
- phenylpropanolamine
- pimavanserin
- pimozide
- pregabalin
- primidone
- procarbazine
- promazine
- propiomazine
- propoxyphene
- protriptyline
Q
R
S
- safinamide
- secobarbital
- selegiline
- sertraline
- sibutramine
- sodium oxybate
- st. john's wort
- sufentanil
- sumatriptan
- suvorexant
T
- tasimelteon
- temazepam
- thioridazine
- thiothixene
- tizanidine
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trimipramine
- tryptophan
V
Z
Tapentadol alcohol/food interactions
There is 1 alcohol/food interaction with tapentadol.
Tapentadol disease interactions
There are 14 disease interactions with tapentadol which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- biliary tract disease
More about tapentadol
- tapentadol consumer information
- Check interactions
- Compare alternatives
- Reviews (425)
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.