Drug Interactions between doxycycline and Rezurock
This report displays the potential drug interactions for the following 2 drugs:
- doxycycline
- Rezurock (belumosudil)
Interactions between your drugs
No interactions were found between doxycycline and Rezurock. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
doxycycline
A total of 207 drugs are known to interact with doxycycline.
- Doxycycline is in the following drug classes: miscellaneous antimalarials, tetracyclines.
-
Doxycycline is used to treat the following conditions:
- Acne
- Actinomycosis
- Amebiasis
- Anthrax
- Anthrax Prophylaxis
- Bacterial Infection
- Bartonellosis
- Bronchiectasis
- Bronchitis
- Brucellosis
- Bullous Pemphigoid
- Cervicitis
- Chancroid
- Chlamydia Infection
- Cholera
- Cutaneous Bacillus anthracis
- Ehrlichiosis
- Enterocolitis
- Epididymitis, Sexually Transmitted
- Gastroenteritis
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Inclusion Conjunctivitis
- Lichen Planopilaris
- Lyme Disease
- Lyme Disease, Arthritis
- Lyme Disease, Carditis
- Lyme Disease, Erythema Chronicum Migrans
- Lyme Disease, Neurologic
- Lymphogranuloma Venereum
- Malaria
- Malaria Prevention
- Melioidosis
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Ornithosis
- Pelvic Inflammatory Disease
- Pemphigoid
- Pemphigus
- Periodontitis
- Plague
- Pleural Effusion
- Pneumonia
- Proctitis
- Prostatitis
- Psittacosis
- Q Fever
- Rabbit Fever
- Rheumatoid Arthritis (off-label)
- Rickettsial Infection
- Rosacea
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Syphilis, Early
- Syphilis, Latent
- Tertiary Syphilis
- Trachoma
- Upper Respiratory Tract Infection
- Urinary Tract Infection
Rezurock
A total of 130 drugs are known to interact with Rezurock.
- Rezurock is in the drug class selective immunosuppressants.
- Rezurock is used to treat Graft-versus-host disease.
Drug and food interactions
belumosudil food
Applies to: Rezurock (belumosudil)
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Administration with food increases the oral bioavailability of belumosudil. The mechanism has not been described. Administration of belumosudil (200 mg single oral dose) in healthy subjects, with a fatty and calorie-rich meal (approximately half of the calories were contained in the fat) increased the mean belumosudil peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by 120% and 100%, respectively, compared to administration under fasting conditions. The time to reach peak concentration (Tmax) was delayed by 30 minutes. Administration of oral belumosudil 200 mg once daily with food in patients with chronic graft-versus-host disease (chronic GVHD) lead to steady-state concentrations of the drug with an accumulation ration of 1.4.
MANAGEMENT: To ensure maximal oral absorption, belumosudil should be administered with a meal, every day at the same time.
References
- (2024) "Product Information. Rezurock (belumosudil)." Sanofi
- (2024) "Product Information. Rezurock (belumosudil)." Kadmon Pharmaceuticals, 11/2023
doxycycline food
Applies to: doxycycline
Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
doxycycline food
Applies to: doxycycline
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.