Phenylephrine Dosage

This dosage information may not include all the information needed to use Phenylephrine safely and effectively. See additional information for Phenylephrine.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hypotension

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.
Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Shock

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.
Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Supraventricular Tachycardia

0.25 to 0.5 mg IV over 30 seconds.

Usual Adult Dose for Nasal Congestion

Tablets or oral liquid: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine 7.5 mg/5 mL oral liquid:
15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine 10 mg oral tablet:
10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine 10 mg oral disintegrating strip:
10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine 10 mg/5 mL oral suspension, extended release:
10 to 20 mg orally every 12 hours.

Phenylephrine tannate 10 mg oral tablet, chewable, extended release:
10 to 20 mg orally every 12 hours.

Phenylephrine tannate 7.5 mg/5 mL oral suspension, extended release
7.5 to 15 mg orally every 12 hours.

Usual Pediatric Dose for Hypotension

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.
IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.
IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Shock

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.
IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.
IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Supraventricular Tachycardia

5 to 10 mcg/kg IV over 30 seconds.

Usual Pediatric Dose for Nasal Congestion

phenylephrine 1.25 mg/0.8 mL oral liquid:
2 years to 5 years: 1.6 mL orally every 4 hours not to exceed 6 doses daily.

Chewable tablets or oral liquid:
6 years to 11 years: 10 mg orally every 4 hours as needed.
12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine 7.5 mg/5 mL oral liquid:
2 years to 5 years: 3.75 mg orally every 6 hours not to exceed 15 mg daily.
6 years to 11 years: 7.5 mg orally every 6 hours not to exceed 30 mg daily.
12 years or older: 15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine 10 mg oral tablet:
12 years or older: 10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine 10 mg oral tablet, disintegrating:
2 years to 5 years: 5 mg orally every 4 hours as needed.
6 years to 11 years: 10 mg orally every 4 hours as needed.
12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine 10 mg/5 mL oral suspension, extended release:
12 years or older: 10 to 20 mg orally every 12 hours.
6 years to 11 years: 5 to 10 mg orally every 12 hours.

Phenylephrine 10 mg oral disintegrating strip:
12 years or older: 10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine tannate 10 mg oral tablet, chewable, extended release:
6 years to 11 years: 5 to 10 mg orally every 12 hours.
12 years or older: 10 to 20 mg orally every 12 hours.

Phenylephrine tannate 7.5 mg/5 mL oral suspension, extended release
2 years to 5 years: 1.25 to 2.5 mL orally every 12 hours.
6 years to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

phenylephrine 1.25 mg oral disintegrating strip:
2 years to 3 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.

phenylephrine 2.5 mg oral disintegrating strip:
2 years to 5 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.
6 years to 11 years: 5 mg orally every 4 hours, not to exceed 30 mg in 24 hours.

phenylephrine 1.25 mg oral tablet, chewable:
12 years or older: 5 mg orally every 4 hours not to exceed 6 doses daily.

phenylephrine 2.5 mg/5 mL oral liquid:
4 years to 5 years: 5 mL orally every 4 hours, not to exceed 6 doses in 24 hours.
6 years to 11 years: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Use with caution in patients with arrhythmias, hyperthyroidism or hyperglycemia.

Do not use in pheochromocytoma or severe hypertension.

Dialysis

Data not available

Questions about Atrial Fibrillation? Get answers from our expert. Watch Video

Close
Hide
(web3)