Skip to Content

Phenylephrine use while Breastfeeding

Drugs containing Phenylephrine: Promethazine VC with Codeine, Preparation H, Neo-Synephrine, Bromfed, Alka-Seltzer Plus Cold, Severe Allergy and Sinus Headache, Preparation H Cream with Maximum Strength Pain Relief, Hemorrhoidal Ointment, Phenergan VC with Codeine, Cough & Cold Relief, Show all 1235 »Deconex DMX, Codal-DM Syrup, Omidria, CapCof, Sudafed PE Pressure + Pain, Norel AD, Rynex DM, Mucinex Fast-Max Severe Congestion & Cough, Promethazine VC w/Codeine, Robitussin Cough & Cold CF, Promethazine VC Plain, Triplex AD, Sudafed PE Congestion, Vicks Sinex Nasal Spray, Dimetapp Children's Cold & Allergy, Deconex, Phenergan VC, Vicks NyQuil Severe Cold & Flu, Benadryl Allergy Plus Cold, Sudafed PE Sinus & Allergy, Giltuss, Vicks Dayquil Cold & Flu Relief, Alka-Seltzer Plus Cold Formula, Tylenol Sinus Congestion & Pain Daytime, Dallergy, Neo-Synephrine Nasal, Histussin HC Syrup, Dimetapp Children's Cold & Cough, Dimetane Decongestant, Zincfrin, Coughtuss, Ed A-Hist DM, Despec DM Syrup, Dristan Cold Multi Symptom Formula, Nasex-G, R-Tanna, Mucinex Fast-Max Night Time Cold & Flu, Nasal Decongestant PE, Dexall, PCM, Rondec, Seradex, Mucus Relief Sinus, Tylenol Cold & Flu Severe, Advil Congestion Relief, Mucinex Sinus-Max Day & Night (Day), Mucinex Fast-Max Severe Congestion & Cold, DCP Drops, NoHist DM, Trital SR, Giltuss Pediatrics, Fentex, Hemorrhoidal, Sinus Congestion & Pain, Codral Cold and Flu + Cough Day and Night, Ceron-DM, Resperal, Dimaphen Elixir, Equate Allergy & Sinus Headache, Actifed Cold and Allergy, Dallergy Drops, Phenylephrine HD, VazoTuss HC, Cardec, Suphedrine PE Severe Cold, Tussin CF, Gestuss-HC, Donatussin, Tridal, Tusicof, Broncotron Ped, Dilotab II, Nuhist, Decon-A, AK-Dilate, Relief, Robitussin Multi-Symptom Cold Maximum Strength, Rynatan, J-Tan D SR, Mucus Relief Complete, Phenavent, Balamine DM, Entex LA, Ricotuss, Tanoral, Tylenol Cold Multi-Symptom Nighttime Liquid, AllerTan, Rondec-DM, Duravent DPB, Tussi-Pres B, Endotuss-HD, Ryna-12, Tylenol Allergy Multi-Symptom, Ditussin-HC, Sudogest PE, Tusana-D, Triall, PD-Cof, Sudafed PE Cold & Cough, Cold Head Congestion, Cold Multi-Symptom Severe, Levall, Rescon-GG, Adult Cold, Flu & Sore Throat, Delsym Cough+ Cold Day Time, Quartuss DM, Sudex, Tetra Tannate Pediatric, Entac, Alahist DM, Rentamine, Robafen CF, Mucinex Sinus-Max Day Time Severe Congestion Relief, Dacex-PE, Altex Liquid, Nortuss-DE, Zotex, M-End PE, Centussin DHC, Extendryl, Endacon, Theraflu Cold & Sore Throat, Extendryl Chews, Alka-Seltzer Plus Cold and Sinus, Vicks Dayquil Sinus, Contac Cold + Flu (Day Formula), PCM Allergy, Otogesic, Deconex IR, Nazarin, Aquatab C, Sitrex PD, Prehist D, Duravent, Tusscough DHC, Banex, Rymed, Bromatan-DM, Novahistine DH, Theraflu Sinus & Cold, Gentex LA, Maxiphen, D-Tann CT, Cerose DM, Brotapp PE-DM, Amitex LA, Hydrocodone HD, Triant-HC, Tritan, Norel SR, Hydrocodone CP, Vanex-HD, Chlorgest HD, Quindal HD, Ru-Hist Forte, Poly Hist PD (old formulation), Mucinex Fast-Max Cold, Flu & Sore Throat, Phenchlor Tannate Pediatric, Phenylhistine, Tylenol Cold Multi-Symptom Severe, Vicks DayQuil Severe Cold & Flu, Relasin-HC, Theraflu Cold & Cough, Sinus & Allergy PE, Ed-TLC, Linhist-LA, Murocoll 2, C-Phen DM Drops, Norel CS, Zoden DM Drops, Nasopen PE, Phenabid DM, Histex-PE, Triaminic Multi-Symptom Fever & Cold, Tussar DM, Father John's Medicine Plus, Quartuss, Promethazine VC, Nalex-A, Poly Hist Forte (old formulation), Hybrid CF, Tri-Vent DPC, Aldex D, Protid, Allerest PE, Suphedrine PE Sinus & Allergy, Tussinate, Aridex-D Pediatric, Rynex PE, J-Tan D, CVS Allergy & Cold, Endal, Seradex-LA, RespaHist II, Bromfed-PD Capsules, Excof-SF, Guiatex PE, Vicks QlearQuil Nighttime Sinus & Congestion, Giltuss TR, Lusair, DMax Pediatric, Benadryl-D Children's Allergy & Sinus, Sinupan, Despec, Alconefrin-25, Vicks Sinex Ultra Fine Mist, Tylenol Cold Multi-Symptom Daytime, Theraflu Multi-Symptom Severe Cold, Sudafed PE Pressure+Pain+Cough, Lohist, Novahistine, AlleRx, Vazculep, PediaCare Children's Decongestant, Prefrin, Phenoptic, Poly Hist DM, Rynatuss, Prolex D, Quintex, Mydfrin, Neo-Synephrine Ophthalmic, AK-Nefrin, DuraMAX, Maxiphen-G DM, Q-Tussin CF, Endacon DM, Despec NR Drops, Desgen, Desgen DM, Mucinex Fast-Max Day Time Severe Congestion & Cough, Tusslin, Mucinex Children's Multi-Symptom Cold, ExeTuss-DM, Tusso-DM, Execof ER, Ambi 40/1000/60, Z-tuss DM, PDM GG, Deconex DM, Mucinex Children's Day Time Multi-Symptom Cold, Duravent DM, Safetussin CD, Children's Triacting Daytime, Triaminic Thin Strips Day Time Cold & Cough, Triaminic Day Time Cold & Cough, Theraflu Thin Strips Daytime Cold and Cough, PediaCare Children's Multi-Symptom Cold, Little Colds Decongestant/Cough, Albatussin Pediatric Drops, Nivanex DMX, Zotex-EX, Hot Lemon Cough and Colds Relief DM, PediaCare Daytime Multi-Symptom Cold, Albatussin Pediatric, Sudafed PE Children's Cold & Cough, Tusso-XR, Z-Dex, Tussex, Pres Gen, Tussafed-EX, GDP-EX, TriTuss-ER, TriTuss, Tussi-Pres Pediatric, G-Tron Ped, Broncotron-D, Tussidex, Supress-DX, Robitussin Peak Cold Multi-Symptom Cold, Tussi-Pres, G-Supress DX, Tussafed-EX Drops, Certuss-D (old formulation), G-Phen DM, Maxiphen DM, Phlemex Forte, Phlemex-PE, Guaphen II DM, Guaphen Forte, Duraphen Forte, Duraphen II DM, Anextuss, Dynatuss EX, Dexcon-PE, Zotex LAX, Dexcon-DM, Dacex-DM, Robitussin Multi-Symptom Cold, Tussall, Equitan Pediatric, Tanoral Pediatric, Triple Tannate Pediatric, Tri-Tannate, Tri-Tannate Pediatric, Tanamine Pediatric, Triotann-S Pediatric, R-Tannamine Pediatric, Rynatan-S Pediatric, Atrohist Pediatric, R-Tannate Pediatric, Gelhist Pediatric, Triotann-S, R-Tannate, Rhinatate Pediatric, Rhinatate, Chlorex-A 12, Triotann Pediatric, Tri-Gestan S, Tri-Hist Pediatric, Tri Tann Pediatric, Phena-Plus, Phena-S, Histatan, Tanamine, Url-Tannate Pediatric, R-Tannamine, URL-Tannate, Triotann, West-Decon M, Coldex, Nalgest, Sinucon Pediatric, West-Decon, Nalspan, Prop-A-Hist, Uni Decon, Nalgestic Pediatric, Nalda-Relief Pediatric, NoHist, Sildec-PE, Maxichlor PEH, Ry-Tann, Nalphen, Hista-Vadrin, Sinucon, Naldelate, Q-Hist LA, Comhist LA, Chlortox, C-Hist-SR, Chlorex A, Nalex-A SR, Comhist, Rhinacon A, Naldecon, Andecon Pediatric Drops, Histalet Forte, Vanex Forte, NoHist-A, Nalex A 12, Conal, Notuss PD, Codimal DH, EndaCof-Plus, Hydex PD, Re-Drylex, CoryZa-D, Zotex HC, P-Hist, Ala-Hist PE, H-C Tussive-NR, Poly Tan D, Donatussin DM Suspension, ProHist, Coryza-DM, DexPhen M, Rescon-MX, Tusso-DMR, Mucinex Children's Congestion & Cough, Pres Gen Pediatric, Duraphen DM, G-Tusicof, Sinutuss DM, Robitussin Children's Cough & Cold CF, D-Tann DM, NalDex, Rescon-Jr, RhinaHist, Dytan-DM, Duratuss AC 12, Cytuss-HC NR, Poly Tan DM, Giltuss Ped-C, Endal CD (old formulation), Maxiphen CD, Maxiphen CDX, Tussirex Sugar Free, Tussirex, Airacof, Vanacof CD, Phena-S 12, Pyrichlor PE, MyHist-PD, Pro-Red AC, Dexphen w/C, Ala-Hist AC, Notuss-PE, Y-Cof DM, G-P-Tuss DXP, Supress A, Panatuss DXP, Supress A Pediatric, Tussall-ER, Panatuss Pediatric DXP, Cyclomydril, Zotex-C, M-Phen, Codimal PH, Pro-Red AC (old formulation), Dicomal-PH, Zotex Pediatric, Hydro GP, Coldloc, Guaifenex, Enomine, Cyntex Liquid, Ryna-12X, Rolatuss with Hydrocodone, A-Tan 12X, Phentex, Equi-Tex, Ami-Tex, Guiatex, Duratex, Phenylfenesin, Dura-Gest, Norel, Ru-Tuss with Hydrocodone, Vetuss HC Syrup, Codituss DH, Hydrophene DH, De-Chlor MR, Mintuss MR, Tussplex, Trimal DH, Codal-DH Syrup, Hyco-DH, Nalex-DH, Tusdec-HC, Lortuss HC, PhendaCof Plus, Dicomal-DH, Hycomal DH, Xedec, Wellbid-D 1200, Phenavent LA, Liquibid-D 1200, Crantex ER, Phenavent D, Deconsal II, Guaifed PD, Guaifed Caps, Liquibid-PD, Duraphen II, Quindal, Chemdal, SINUvent PE, Crantex, Entex ER, Crantex LA Capsules, Sina-12X, Tussbid, Duratuss, ED Bron GP, Duratuss GP, Sitrex, Wellbid-D, Guaiphen-PD, Crantex LA Tablets, Nasex, Nescon-PD, Phenavent PED, Pendex, Prolex PD, Duravent PE, Aldex, Poly Hist HC, Duo-Medihaler, Hemorid Maximum Strength, Hemorid Ointment, KGS-PE, Hemorid Cream, Myci Spray, Viravan-T, Deconsal CT, Medicone Hemorrhoidal, Anu-Med, Hemorid, Anusert Ointment, Formulation R, Prompt Relief, Hemorrhoidal Cooling Gel, Prep-Hem, K-Tan 4, K-Tan, Ryna-12S, Pyrlex PD, Ru-Hist D (old formulation), Pyril D, Prohist LQ, Vasosulf, Rynesa 12S, Deconsal CT Tannate, R-Tannic-S A/D, Pyril Mal Phenyl HCl, Pyril Tann-12, Viravan-S, Ry-T-12, V-Tann, Sudafed PE Children's Nasal Decongestant, Ricobid-D, Rhinall, 4-Way Menthol, 4 Way Fast Acting Nasal Spray, Nasal Four, Isopto Frin, Refresh Redness Relief, Ocu-Phrin, Neo-Synephrine Mild Nasal, Neo-Synephrine Extra Strength Nasal, Extendryl PEM, AlleRx Dose Pack PE (AM Dose), Alconefrin-12, Nostril Nasal Decongestant, Little Noses Decongestant, Afrin 4 Hour Extra Moisturizing, Altafrin, Neofrin, Gilchew IR, AH-Chew D, Little Colds Decongestant, Lusonal, Nasop, Contac-D, Congest Aid II, Dimetapp Toddler's Drops Decongestant, Help I Have A Stuffy Nose, Suphedrine PE, Despec-SF, Nasop12, Phenyl-T, Triaminic Thin Strips Cold with Stuffy Nose, Amidal, Efasin, D-Tann, Pediatex-CT, Dytan-D, Benadryl-D Allergy Plus Sinus, PediaCare Children's Allergy & Cold, S-T Forte, Poly Hist Forte, Alahist LQ, Robitussin Night Time Cough & Cold, Triaminic Thin Strips Night Time Cold & Cough, Diphenmax D, Dimetapp Children's Nighttime Cold & Congestion, Children's Triacting Night Time, Theraflu Thin Strips Nighttime Cold and Cough, Triaminic Night Time Cold & Cough, Mintuss G, Atuss G, Duratuss HD, Crantex HC, Simuc-HD, Gentex HC, Guiaplex HC, Donatussin DC, Uni-Lev 5.0, Tussafed-HCG, Tussafed-HC, Ambi 5/15/100, Levall 5.0, Acta-Tabs PE, Dynatuss HC, De-Chlor G, Aldex-CT, Uni-Tann D, Reme Hist DM, Codituss DM, Codimal DM, Pryil DM, MyHist-DM, Ru-Hist Plus, Tannate V DM, Triplex DM, Viratan-DM, Viravan-DM, Dimetapp Toddler's Drops Decongestant Plus Cough, V-Tan DM, Zotex-12, Aldex DM, Deconsal DM Tannate, Deconsal DM, Histex-DM, D-Tann HC, Dytan-HC, Delsym Children's Night Time Cough & Cold, PediaCare Nighttime Multi-Symptom Cold, Diphentann-D, Sudafed PE Nighttime Nasal Decongestant, Endal HD, Rindal HPD, Poly Tussin EX, Poly-Tussin EX Syrup, Donatuss DC, Alahist DHC, Hydro-DP, Poly Hist DHC, Exetuss-HC, Qual-Tussin DC, Aquatab D, Entex LQ, Guiadex PD, Respa-PE, Sudafed PE Non-Drying Sinus, Liquibid PD-R, Liquibid D-R, Visonex, Mucinex Children's Stuffy Nose & Cold, Genexa LA, Medent-PE, Ambi 40/1000, J-Max, D-Phen 1000, Medent-PEI, D-Tab, ExeTuss, PE-Guai, Zyrphen, Chest Congestion Relief PE, Tussi-Pres PE, Mucus Relief PE, Deconsal Pediatric, Dimetapp Children's Cold & Chest Congestion, Supress-PE, MucaphEd, ExeTuss-GP, Fenesin PE IR, Reese Onetab Congestion & Cough, Gilphex TR, Nu-COPD, Mydex, Refenesen Chest Congestion Relief PE, Zotex GPX, Simuc, Duomax, Guaifen PE, Aldex G, Norel EX, Donatussin Drops, Guaiphen-D 1200, MonteFlu HC, Nariz HC, Nazarin HC, HydroFed, Guaiphen-D 600, Xpect-PE, Nexphen PD, Reluri, Liquibid-D, Xedec II, Simuc-GP, Zotex-GP, Duratuss PE, Triaminic Chest & Nasal Congestion, MontePhen, Guaphenyl LA, Duraphen 1000, Nariz, Lusonex, Dynex LA, Extendryl G, Miraphen PE, Vicks Formula 44 Custom Care Congestion, QV-Allergy, EndaCof-PD, Allanhist PDX Syrup, Uni-Hist PDX Syrup, Bromhist-PDX, BroveX PB DM, Alacol DM, BPM DM PHEN, AccuHist PDX Syrup, Poly-Tussin AC, Trexbrom, Pulmari, Vazotan, SymPak II, BroveX PB C, TL-Hist CD, BroveX PB CX, BP Allergy DM, Presgen B, Balacall DM, LoHist PEB DM, BPM PE DM, Lohist-DM, DuraTan DM, AP-Hist DM, EndaCof-DM, BroveX PEB DM, Cold & Cough Childrens, TL-Hist DM, Y-COF DMX, Tusdec-DM, Bromtuss DM, Dimaphen DM, Dur-Tann DM, BetaTan, V-COF, Non-Pseudo Sinus Pain & Pressure, Mapap Sinus Congestion and Pain, Congespirin Aspirin Free, Sinutab Sinus Maximum Strength, Rolatuss, Tympagesic, Quelidrine, Day Relief Sinus PE, D-Time Sinus, Tylenol Plus Children's Cold & Stuffy Nose, Sinus Congestion and Pain Daytime Cool Ice, Suphedrine PE Sinus Headache, Vicks QlearQuil Daytime Sinus & Congestion, Excedrin Sinus Headache, Robitussin Peak Cold Nasal Relief, Chlorphenylcaine, Alka-Seltzer Plus Cold & Cough Formula, Bellahist-D LA, AccuHist LA, Ex-Tuss, Histacol LA, Sta-D, Trexbrom (old formulation), Spec-T Sore Throat/Decongestant Lozenges, Protuss Tablet, Rolatuss-SR, Alka-Seltzer Plus Day & Night Cold Formula (Night Cold), Alka-Seltzer Plus Night Cold Formula, Alka-Seltzer Plus Day & Night Cold Formula (Day Cold), Alka-Seltzer Plus Sinus Formula, Deconhist LA, Atrohist Plus, Poly-Tussin DHC, EndaCof-DH, Quad Tann Pediatric, Quad Tuss Pediatric, Tuss Tan Pediatric, Quad Tann, Tannic-12, Tannate-12, Carbaphen 12, Tuss Tan, Rentamine Pediatric, Scot-Tussin Original (old formulation), Dime Time Extended Release, Vazobid-PD, Aridex, Quad-Tuss, Quadratuss, Rynatuss Pediatric, XiraTuss, Tanni-Hist 12 RF, Carbatuss, Gentex 30, Gentex LQ, Carbatab-12, Oratuss 12, Phencarb GG, Carbetaplex, Extendryl GCP, Albatussin, Corzall-PE, Exratuss, Dytan-CS, D-Tann CD, Dytan-CD, Uni-Tann CS, Tanabid SR, Brotapp PE, BPM PE, Rhinabid PD, Bromfenex PE Pediatric, B-Vex D, Bromaphedrine D, VaZol-D, Alenaze-D NR, Bromfenex PE, Rhinabid, VasoTuss HC, Ala-Hist D, BPM PE HC, Canges-HC NR, Canges-HC, FluTuss HC, VazoBid, BroveX PB, Phenyl 7.5/6mg, V-HIST, Zotex-PE, Phenyl 15/12mg, Brom Tann PE, Alenaze-D, Brohist D, Ru-Hist D, BroveX PEB, Entre-B, Alacol, LoHist PEB, BroveX-D, BroveX ADT, Vazotab, Scot-Tussin Original, Theraflu Flu & Sore Throat, Rhinogesic, Covangesic, Dryphen, Phenflu CDX, Phenflu CD, Respa C&C IR, Respa C&C, HEB Allergy, Alka-Seltzer Plus Cold & Flu, Comtrex Flu Therapy, Comtrex Severe Cold & Sinus, Tylenol Sinus Congestion & Pain Nighttime, Tylenol Plus Children's Cold, XL-3 Cold Medicine, Tylenol Sinus Congestion and Pain Cool Burst Day Night, Sine-Off Sinus/Cold, Delsym Night Time Multi-Symptom, Alka-Seltzer Plus Night Cold Formula Liquid Gels, Tylenol Cold Head Congestion Severe (old formulation), CounterAct Day, Non-Pseudo Cold Relief, Phenflu DM, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Mucus Relief Plus, ConRx Cold, Mucinex Fast-Max Severe Cold, Mucinex Fast-Max Day Time Severe Cold, Alka-Seltzer Plus Night Cold Formula Liquid, Alka-Seltzer Plus Day & Night Cold Formula (Night Cold) Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Night Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough (Night Formula), Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Children's Cold, Cough & Sore Throat, Gendecon, GNP Cold Relief Plus, Tylenol Cold Head Congestion Nighttime, Tylenol Cold Multi-Symptom Nighttime, PediaCare Flu Plus Acetaminophen, Comtrex Cold & Cough Day Night, Theraflu Nighttime Severe Cold & Cough Caplets, Comtrex Nighttime Cold & Cough, Tylenol Cold Head Congestion Day and Night, Alka-Seltzer Plus Cold & Cough Formula Liquid, PediaCare Multi-Symptom Cold Plus Acetaminophen, Colrex Compound, Emagrin Forte (old formulation), Colrex, Tylenol Plus Children's Multi-Symptom Cold, Alka-Seltzer Plus Cold & Cough Formula Liquid Gels, Tylenol Plus Children's Flu, Dimetapp Children's Multi-Symptom Cold & Flu, XL-3 Xtra Cold and Cough, Allergy Multi-Symptom, Allergy Sinus PE Pain Relief, Allergy Pain Relief, Pyrroxate, Robitussin Peak Cold Nighttime Nasal Relief, Onset Forte, Relief-PE, ConRx Allergy Sinus, Contac Cold + Flu (Night Formula), Multi Symptom Cold (Night Formula), Cold Multi-Symptom (Nighttime), Multi Symptom Cold Relief, Alka-Seltzer Plus Flu Formula, Theraflu Warming Relief Nighttime Multi-Symptom Cold Caplets, Dimetapp Children's Nighttime Flu, Cold & Cough PE Multi-Symptom, Suphedrine PE Cold & Cough, Tylenol Allergy Multi-Symptom Nighttime, Benadryl Severe Allergy Plus Sinus Headache, Theraflu Warming Relief Flu & Sore Throat, CVS Allergy & Sinus Headache, Children's Tylenol Plus Cold And Allergy, Benadryl Allergy Plus Sinus Headache, Theraflu Warming Relief Sinus & Cold, Theraflu Nighttime Severe Cold & Cough, Robitussin Peak Cold Nighttime Multi-Symptom Cold, Robitussin Multi-Symptom Cold Night Time, CounterAct Night, Mucinex Children's Night Time Multi-Symptom Cold, Mucinex Sinus-Max Day & Night (Night), Robitussin Night Time Cough, Cold & Flu, Sudafed PE Nighttime Cold, Vicks Nyquil Sinus, Alka-Seltzer Plus Severe Allergy Sinus Congestion & Headache, Emagrin Forte, Theraflu Warming Relief Cold and Chest Congestion, Histenol-Forte II, Tylenol Cold Head Congestion Severe, Sudafed PE Triple Action, Sudafed PE Pressure+Pain+Mucus, Coldonyl, ConRx Sinus, Mucinex Sinus-Max Severe Congestion Relief, Tylenol Sinus Congestion & Pain Severe, Beechams All-in-One, Duratuss-A, LuSonex Plus, Mucinex Sinus-Max Pressure & Pain, Mucinex Fast-Max Cold & Sinus, Mucinex Sinus-Max Night Time Congestion & Cough, Delsym Children’s Cough+ Cold Night Time, Alka-Seltzer Plus Day Non-Drowsy Cold Formula Liquid Gels, Mapap Cold Formula, Comtrex Cold & Cough, Alka-Seltzer Plus Day & Night Cold Formula (Day Cold) Liquid Gels, Little Colds Multi-Symptom, Vicks Nature Fusion Cold & Flu Multi-Symptom Relief, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Day Formula), Robitussin Cold + Flu (Daytime), Neocitran Non Drowsy Extra Strength Cold and Flu, Tylenol Cough & Severe Congestion Daytime, Sudafed PE Pressure+Pain+Cold, Robitussin Peak Cold Daytime Cold + Flu, Daytime Cold & Flu, Tylenol Plus Children's Cold & Cough, Contac Complete Cough, Cold & Flu Extra Strength, Theraflu Daytime Severe Cold & Cough, Comtrex Cold and Cough Maximum Strength, Flu & Severe Cold & Cough Daytime Powder, Tylenol Cold Head Congestion Daytime, Theraflu Warming Relief Daytime Severe Cold & Cough, Tylenol Plus Children's Cold & Allergy, Sudafed PE Severe Cold, Delsym Cough+ Cold Night Time, Theraflu Warming Relief Nighttime Severe Cold & Cough, Theraflu Warming Relief Daytime Multi-Symptom Cold Caplets, Cold Multi-Symptom (Daytime), Vicks Dayquil Cold & Flu Symptom Relief Plus Vitamin C, Day Relief PE, Day Time Multi-Symptom Cold/Flu Relief, Multi Symptom Cold (Day Formula), Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Alka-Seltzer Plus Severe Sinus Congestion & Cough (Day Formula), MonteCough, L-All 12, AlleRx Dose Pack (PM Dose), ScopoHist Syrup, RelCof PE, Allergy DN PE, DuraTan PE, Nohist Plus Jr, Nohist Plus, RelCof DN PE, Nohist PE, Maxi-Tuss HCX, Z-Cof HC, DroTuss-CP, Relacon-HC, Advil Allergy and Congestion Relief, DriHist SR, Dehistine, Dallergy SR, Duradryl Chewable, Omnihist L.A., DA Chewable, Extendryl SR, Duravent DA, Hista-Vent DA, Liqui-Allergy, DA II, Sinodec, ScopoHist-PE, Duradryl SR, Aerohist Plus, Dallergy PE, CPM-PE-MSC, SymPak PDX, Ah-Chew Ultra Tannate, Liquicough HC, Poly-Tussin HD, Cytuss HC, Histussin HC Liquid, H-C Tussive, Tuss-DS, Efasin-HD Plus, Hi-Tuss HC, Quindal HD Plus, Uni Tuss HC, Highland HC, Ventuss Syrup, Tuss-HC, Maxi-Tuss SA, Maxi-Tuss HC, KG-Dal HD Plus, Histinex HC, Chlorphen HD, Duradal HD, Rindal HD Plus, Uni-Tricof HC, Hydro-PC II Plus, Echotuss-HC, Phendal-HD, Neo HC, Relacon-HC NR, Atuss MS, De-Chlor HC, Tussive HC, Liquitussin HC Syrup, B-Tuss, Hydro-PC II, De-Chlor HD, Hydron CP, AH-Chew, Duradryl, Ceron Drops, PD-Hist D Drops, Ceron, PD-Hist D, Tanahist-D, CP Dec Drops, Allan Tannate Pediatric, Nasohist Pediatric, Rynatan Pediatric, AccuHist Drops, Trigofen Drops, Rhinatate-NF, Ed A-Hist, Novahistine Elixir, Ed A-Hist LA, Histatab Plus, Chlor-Mes Jr, Rondex, P-Tann D, Cardec Drops, CP Dec, Triaminic Cold & Allergy, ChlorTan D, Ed ChlorPed D, Rinate Pediatric, PediaTan D, Histadec, Dec-Chlorphen, Rondex Drops, Dec-Chlorphen Drops, C Phen Drops, Tannate Pediatric, C Phen, Ny-Tannic, Virdec, Ralix, AH-Chew II, Omnihist II LA, Denaze, Aerokid, Extendryl Seniors, Dallergy ER, Durahist PE, Norel SD, Drize, Duradryl JR, Drysec, Ex-Histine, Chlor-Mes D, WE Allergy, Hycomine Compound, Rescon Extended Release, Relera, Dallergy JR, AlleRx Dose Pack, NoHist LQ, Sonahist, BP Allergy JR, Ricobid NR, DriHist, Extendryl JR, Redur-PCM, AlleRx Dose Pack PE (PM Dose), Ah-chew Ultra, Histatab PH, Re-Drylex Jr, Chlor-Mes, Comtussin HC, Enplus-HD, Broncopectol, SymPak DM, Demi-Cof, ChlorDex GP, Qual-Tussin, Zotex-DM, Genelan NF, Pedituss, Pediacof, Prohist CD, Vanacof APE, Pro-Chlo, Nasotuss, Dallergy Syrup, T- Koff, Endal CD, Donatussin DM, Ceron-DM Drops, Tussplex DM, Reme Tussin DM, Cardec DM Drops, Cardec DM, C-Phen DM, Sildec-PE DM Drops, Robitussin Cough & Allergy, Nasohist-DM Pediatric, Neo DM Drops, Rondex-DM Drops, Rondex-DM, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, CP Dec DM, HistadecDM, Vanacof GPE, Chlophed, Tannate 12D S, Tannihist-12D, C-Tanna 12D, Tussi-12D, DMax, Dacex-A, TriTuss-A Drops, Tussi-12D S, Carbatuss-CL, Carbetaplex TS, Re All 12, L-All 12 NF, Levall-12, Cophene-X, Uni All 12, XiraHistDM, X-Hist DM, X-Hist, Aridex-D, HistamaxD, Phenagil CH, Carbaphen CH, Chlo Tuss (old formulation), DryMax AF, XiraHist, Norel LA, DMax Syrup, DMax Pediatric Drops, Trituss-A, Excof, Max HC, Donatussin MAX, Sildec-PE DM, EndaCof Drops, SymPak, Duohist DH, Despec-PD, P Chlor GG, Donatussin Pediatric, Endagen-HD, Qual-Tussin Pediatric, Pancof-PD, Coldcough PD, Mintuss DR, Uni-Tuss DM, Trital DM, P Chlor DM, DiHydro-PE, Dex PC, Chemdal HD, Iodal HD, Tuss-PD, Hyphen-HD, Cyndal HD, KG-Dal HD, Chemtussin HC, Endal-HD Plus, Exo-Tuss, Ed-Tuss HC, Iotussin HC, Efasin-HD, Rindal-HD, Guiaphen HD, Mintuss MS, Nasatuss, Chemdal HD Plus, Corfen-DM, Atuss DR, RE DCP Drops, Sonahist-DM, Re DCP, Nohist-DMX, Bronkids, Nasohist-DM, Donatussin DM Drops, Virdec DM, Trigofen DM Drops, Maxichlor PEH DM, PE-Hist DM, ED DM, Poly-Tussin DM, Z-Dex 12 D, Tri-Dex PE, DM-PE-Chlor, CP Dec-DM Drops, Norel DM, Atuss DM, Centergy DM, NeoTuss Plus, De-Chlor DM, Coldtuss-DR, De-Chlor DR, Liquituss R-DM, Maxiphen ADT, Zotex-12D, PD-Cof Drops, Statuss DM, NoHist-PDX, Albatussin SR, Relahist-DM, Sildec-PE Drops

Phenylephrine Levels and Effects while Breastfeeding

Summary of Use during Lactation

The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. However, intravenous or oral administration of phenylephrine might decrease milk production. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Phenylephrine nasal spray or ophthalmic drops are less likely to decrease lactation. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information in humans was not found as of the revision date. However, animal data indicate that phenylephrine can decrease milk production[2][3] and pseudoephedrine, a pharmacologically similar vasoconstrictor, decreases milk production in nursing mothers after oral use.[4]

Alternate Drugs to Consider

Oxymetazoline

References

1. Eccles R. Substitution of phenylephrine for pseudoephedrine as a nasal decongeststant. An illogical way to control methamphetamine abuse. Br J Clin Pharmacol. 2007;63:10-4. PMID: 17116124

2. Bruckmaier R, Mayer H, Schams D. Effects of alpha- and beta-adrenergic agonists in intramammary pressure and milk flow in dairy cows. J Dairy Res. 1991;58:411-9. PMID: 1684977

3. Inderwies T, Pfaffl MW, Bruckmaier RM. Milking characteristics and their relation to adrenergic receptor mRNA expression and ligand binding in the mammary gland of dairy cows. Domest Anim Endocrinol. 2003;25:275-86. PMID: 14550511

4. Aljazaf K, Hale TW, Ilett KF et al. Pseudoephedrine: effects on milk production in women and estimation of infant exposure via breastmilk. Br J Clin Pharmacol. 2003;56:18-24. PMID: 12848771

Phenylephrine Identification

Substance Name

Phenylephrine

CAS Registry Number

59-42-7

Drug Class

Adrenergic Agents

Adrenergic Alpha-Agonists

Antiglaucoma Agents

Sympathomimetics

Vasoconstrictor Agents

Nasal Decongestants

Administrative Information

LactMed Record Number

556

Last Revision Date

20150310

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

Hide