Generic name: lanthanum carbonate
Dosage form: tablet, chewable
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Divide the total daily dose of FOSRENOL and take with or immediately after meals. The recommended initial total daily dose of FOSRENOL is 1500 mg. Titrate the dose every 2-3 weeks until an acceptable serum phosphate level is reached. Monitor serum phosphate levels as needed during dose titration and on a regular basis thereafter.
In clinical studies of ESRD patients, FOSRENOL doses up to 4500 mg were evaluated. Most patients required a total daily dose between 1500 mg and 3000 mg to reduce plasma phosphate levels to less than 6.0 mg/dL. Doses were generally titrated in increments of 750 mg/day.
Chew or crush tablets completely before swallowing. Do not swallow intact tablets.
Consider crushing tablets completely for patients with poor dentition.
Consider potential drug interactions when prescribing FOSRENOL [see Drug Interactions (7)].