Fluticasone Nasal Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Rhinitis

Nonallergic rhinitis:
Fluticasone propionate:
Initial dose: 200 mcg per day given as 2 sprays (50 mcg propionate per spray) to each nostril daily or 1 spray to each nostril twice daily; dosage may be reduced to 100 mcg/day (1 spray to each nostril daily) after the first few days if symptoms are controlled. Maximum dose: 200 mcg/day (4 sprays/day).

Usual Adult Dose for Allergic Rhinitis

Allergic rhinitis:
Fluticasone propionate
Initial dose: 200 mcg propionate per day given as 2 sprays (50 mcg propionate per spray) to each nostril daily or 1 spray to each nostril twice daily. Dosage may be reduced to 100 mcg propionate/day (1 spray to each nostril daily) after the first few days if symptoms are controlled. Maximum dose: 200 mcg propionate/day (4 sprays/day).

Fluticasone furoate
110 mcg furoate per day given as 2 sprays (27.5 mcg furoate per spray) to each nostril daily. Dosage may be reduced to 55 mcg furoate/day (1 spray to each nostril daily) after the first few days if symptoms are controlled. Maximum dose: 110 mcg furoate (4 sprays/day).

Usual Pediatric Dose for Rhinitis

Nonallergic rhinitis:
fluticasone propionate:
4 years to 11 years: 100 mcg/day given as 1 spray (50 mcg/spray) to each nostril daily. If response is inadequate, give 2 sprays to each nostril daily; once symptoms are controlled, reduce dose to 100 mcg/day (1 spray to each nostril daily). Maximum dose: 200 mcg/day (4 sprays/day).
12 years or older: 1 or 2 sprays (50 mcg/spray) to each nostril once or twice a day as needed to control symptoms of seasonal allergic rhinitis

Usual Pediatric Dose for Allergic Rhinitis

allergic rhinitis:
fluticasone propionate:
4 years to 11 years: 100 mcg/day given as 1 spray (50 mcg/spray) to each nostril daily. If response is inadequate, give 2 sprays to each nostril daily; once symptoms are controlled, reduce dose to 100 mcg/day (1 spray to each nostril daily). Maximum dose: 200 mcg/day (4 sprays/day).
12 years or older: 1 or 2 sprays (50 mcg/spray) to each nostril once or twice a day as needed to control symptoms of seasonal allergic rhinitis

fluticasone furoate:
2 years to 11 years: 55 mcg furoate per day given as 1 spray (27.5 mcg furoate per spray) to each nostril daily. Children not responding to 55 mcg may use 110 mcg per day given as 2 sprays to each nostril. Dosage may be reduced to 55 mcg furoate/day (1 spray to each nostril daily) after the first few days if symptoms are controlled. Maximum dose: 110 mcg furoate (4 sprays/day).
12 years or older: 110 mcg furoate per day given as 2 sprays (27.5 mcg furoate per spray) to each nostril daily. Dosage may be reduced to 55 mcg furoate/day (1 spray to each nostril daily) after the first few days if symptoms are controlled. Maximum dose: 110 mcg furoate (4 sprays/day).

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Intranasal corticosteroids may cause a reduction in growth velocity when administered to pediatric patients.

The concomitant use of intranasal corticosteroids with other inhaled corticosteroids could increase the risk of signs or symptoms of hypercorticism and/or suppression of the HPA axis.

Dialysis

Data not available

Other Comments

Fluticasone intranasal requires regular administration to be effective and is not effective when used on an "as needed" basis. Maximum benefit may not occur for several days.

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