Famotidine / Ibuprofen Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Osteoarthritis

Famotidine-ibuprofen 26.6 mg-800 mg: 1 tablet orally 3 times daily

Usual Adult Dose for Rheumatoid Arthritis

Famotidine-ibuprofen 26.6 mg-800 mg: 1 tablet orally 3 times daily

Renal Dose Adjustments

CrCl less than 50 mL/min: Contraindicated due to increased half-life of famotidine in these patients.

Liver Dose Adjustments

A patient with symptoms suggesting liver dysfunction, or with abnormal liver test values, should be evaluated for evidence of the development of a more severe hepatic reaction while on therapy with famotidine-ibuprofen. If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur (e.g., eosinophilia, rash), famotidine-ibuprofen should be discontinued.

Precautions

Symptomatic response to therapy with famotidine-ibuprofen does not preclude the presence of gastric malignancy.

Patients should be instructed that if a dose is missed, it should be taken as soon possible. However, if the next scheduled dose is due, the patient should not take the missed dose, and should be instructed to take the next dose on time. Patients should be instructed not to take two doses at one time to make up for a missed dose.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

Tablets should be swallowed whole, not chewed, divided, or crushed.

Famotidine-ibuprofen should be taken for the shortest duration consistent with good patient management.

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