Exemestane Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Breast Cancer

For early and advanced breast cancer:

Recommended dose: 25 mg orally once daily after a meal.

In postmenopausal women with early breast cancer who have been treated with two to three years of tamoxifen, treatment with exemestane should continue in the absence of recurrence or contralateral breast cancer until completion of five years of adjuvant endocrine therapy.

For patients with advanced breast cancer, treatment with exemestane should continue until tumor progression is evident.

Renal Dose Adjustments

Dosage adjustment does not appear to be necessary.

Liver Dose Adjustments

Dosage adjustment does not appear to be necessary.

Precautions

The safety of chronic dosing in patients with moderate or severe hepatic or renal impairment has not been studied.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Dosage adjustment does not appear to be necessary.

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