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Exemestane Dosage

Applies to the following strength(s): 25 mg

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Breast Cancer

25 mg orally once a day

Comment:
-This drug should be administered after a meal.

Uses:
-Adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to exemestane for completion of a total of five consecutive years of adjuvant hormonal therapy.
-Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dose Adjustments

Patients taking exemestane with a potent CYP450 3A4 inducer such as rifampin or phenytoin: 50 mg once a day after a meal

Precautions

Safety and efficacy have not been established in patients younger than 18 years of age.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Monitoring:
-Bone mineral density (BMD) in women with or at risk of developing osteoporosis

Patient advice:
-Exemestane may cause dizziness, asthenia, and somnolence. Patients should avoid driving or operating machinery if they experience these adverse effects.

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