Aromasin

Generic Name: exemestane (ex e MES tane)
Brand Names: Aromasin

What is Aromasin?

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Aromasin lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow.

Aromasin is used to treat advanced breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen for 2 to 3 years.

Aromasin may also be used for other purposes not listed in this medication guide.

Important information about Aromasin

FDA pregnancy category D. Aromasin can cause harm to an unborn baby. Do not use this medication without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

You may need to take a pregnancy test before using Aromasin, to make sure you are not pregnant.

You also should not use this medication if you are breast-feeding a baby, or if you are allergic to exemestane.

Before using Aromasin, tell your doctor if you have severe liver or kidney disease, or if you have not yet completed menopause. If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

You may need to keep taking Aromasin for up to 5 years. Follow your doctor's instructions.

Aromasin may not work as well if you take it together with tamoxifen or an estrogen medication. Before you start taking this medication, tell your doctor if you also take tamoxifen or estrogen.

Before taking Aromasin

You should not use this medication if you are allergic to exemestane, or if you are pregnant or breast-feeding.

Before using Aromasin, tell your doctor if you are allergic to any drugs, or if you have:

• severe liver disease;

• severe kidney disease; or

• not yet completed menopause.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Aromasin.

FDA pregnancy category D. Aromasin can cause harm to an unborn baby. Do not use Aromasin without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

You may need to take a pregnancy test before using this medication, to make sure you are not pregnant.

It is not known whether Aromasin passes into breast milk or if it could harm a nursing baby. Do not use Aromasin without telling your doctor if you are breast-feeding a baby.

How should I take Aromasin?

Take Aromasin exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Aromasin is usually taken once per day. You may need to keep taking take Aromasin for up to 5 years. Follow your doctor's instructions.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include stomach pain, nausea, vomiting, or blood in your stools.

What should I avoid while taking Aromasin?

Aromasin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Aromasin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• swollen glands;

• a bone fracture; or

• swelling in your hands or feet;

Less serious side effects may include:

• hot flashes;

• joint pain or stiffness;

• weakness, tired feeling;

• headache;

• sleep problems (insomnia); or

• increased sweating.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Aromasin?

Aromasin may not work as well if you take it together with tamoxifen or an estrogen medication.

Before you start taking Aromasin, tell your doctor if you use any of the following drugs:

• rifampin (Rifadin, Rimactane, Rifater);

• St. John's wort;

• a barbiturate such as phenobarbital (Luminal, Solfoton); or

• seizure medication such as carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin).

This list is not complete and there may be other drugs that can interact with Aromasin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about Aromasin.

What does my medication look like?

Exemestane is available with a prescription under the brand name Aromasin. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Aromasin 25 mg - round, off-white to slightly gray tablets

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2008 Cerner Multum, Inc. Version: 1.06. Revision Date: 03/04/2008 1:31:44 PM.

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