Colesevelam Dosage

This dosage information may not include all the information needed to use Colesevelam safely and effectively. See additional information for Colesevelam.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hyperlipoproteinemia Type IIa (Elevated LDL)

Monotherapy or combination therapy with an HMG-CoA reductase inhibitor: Initial dose: 1875 mg (3 tablets) orally twice a day with meals or 3750 mg (6 tablets) orally once a day with a meal.

The recommended dose of colesevelam for oral suspension is one 3.75 gram packet once daily or one 1.875 gram packet twice daily (mixed with 4 to 8 ounces of water, fruit juice, or diet soft drinks).

Usual Adult Dose for Diabetes Type 2

Tablets: 1875 mg (3 tablets) orally twice a day with meals or 3750 mg (6 tablets) orally once a day with a meal.

Oral suspension: one 3.75 gram packet once daily or one 1.875 gram packet twice daily (mixed with 4 to 8 ounces of water, Monotherapy or combination therapy with an HMG-CoA reductase inhibitor: Initial dose: 1875 mg (3 tablets) orally twice a day with meals or 3750 mg (6 tablets) orally once a day with a meal.

The recommended dose of colesevelam for oral suspension is one 3.75 gram packet once daily or one 1.875 gram packet twice daily (mixed with 4 to 8 ounces of water, fruit juice, or diet soft drinks).

Usual Pediatric Dose for Hyperlipidemia

10 to 17 years of age:
Tablets: 1875 mg two times daily or 3750 mg daily with a meal
Oral suspension: one 3.75 gram packet once daily or one 1.875 gram packet twice daily (mixed with 4 to 8 ounces of water).

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and effectiveness have not been established in pediatric patients less than 10 years old.

Dialysis

Data not available

Other Comments

To avoid esophageal distress, colesevelam should be administered with liquid during a meal.

Colesevelam may be dosed at the same time as a statin or the two drugs may be dosed apart.

After initiation of colesevelam, lipid levels should be analyzed within 4 to 6 weeks.

Colesevelam powder packets for oral suspension preparation: empty the entire contents of one packet into a glass or cup. Add 1/2 to 1 cup (4 to 8 ounces) of water, fruit juice, or diet soft drinks. Stir well and drink.

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