Coagulation Factor Viia Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hemophilia A

Treatment of bleeding episodes in hemophilia A or B with inhibitors:
90 micrograms/kg by intravenous bolus injection every 2 hours until hemostasis is achieved. Post-hemostatic dosing every 3 to 6 hours for severe bleeds.

Prevention of bleeding in surgical interventions or invasive procedures in hemophilia A or B with inhibitors:
90 micrograms/kg by intravenous injection immediately before surgery and every 2 hours during surgery. Post-surgical dosing: For minor procedures, dosing every 2 hours for 48 hours and then every 2 to 6 hours, and for major procedures every 2 hours for the first 5 days and then every 4 hours, until healing has occurred.

Acquired hemophilia - bleeding episodes or surgery:
70 to 90 micrograms/kg by intravenous bolus injection every 2 to 3 hours until hemostasis is achieved.

Usual Adult Dose for Hemophilia B

Treatment of bleeding episodes in hemophilia A or B with inhibitors:
90 micrograms/kg by intravenous bolus injection every 2 hours until hemostasis is achieved. Post-hemostatic dosing every 3 to 6 hours for severe bleeds.

Prevention of bleeding in surgical interventions or invasive procedures in hemophilia A or B with inhibitors:
90 micrograms/kg by intravenous injection immediately before surgery and every 2 hours during surgery. Post-surgical dosing: For minor procedures, dosing every 2 hours for 48 hours and then every 2 to 6 hours, and for major procedures every 2 hours for the first 5 days and then every 4 hours, until healing has occurred.

Acquired hemophilia - bleeding episodes or surgery:
70 to 90 micrograms/kg by intravenous bolus injection every 2 to 3 hours until hemostasis is achieved.

Usual Adult Dose for Factor VII Deficiency

Congenital FVII Deficiency - Bleeding Episodes or Surgery:
15 to 30 micrograms/kg every 4 to 6 hours until hemostasis is achieved.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

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