Ciclopirox Topical Dosage

Usual Adult Dose for Onychomycosis - Fingernail

8% topical solution:
Apply once daily (preferably at bedtime or 8 hours before washing) to all affected nails with the applicator brush provided. Apply evenly over the entire nail plate and 5 mm of surrounding skin.

If possible, apply to the nail bed, hyponychium, and the under surface of the nail plate when it is free of the nail bed.

Do not remove product on a daily basis. Make daily applications over the previous coat and remove with alcohol every 7 days. Repeat this cycle throughout the duration of treatment.

Up to 48 weeks of daily applications and professional removal, as frequently as monthly, of the unattached, infected nail are considered the full treatment to achieve a clear or almost clear nail. Six months of therapy with professional removal of the unattached, infected nail may be required before initial improvement of symptoms is noticed.

Usual Adult Dose for Onychomycosis - Toenail

8% topical solution:
Apply once daily (preferably at bedtime or 8 hours before washing) to all affected nails with the applicator brush provided. Apply evenly over the entire nail plate and 5 mm of surrounding skin.

If possible, apply to the nail bed, hyponychium, and the under surface of the nail plate when it is free of the nail bed.

Do not remove product on a daily basis. Make daily applications over the previous coat and remove with alcohol every 7 days. Repeat this cycle throughout the duration of treatment.

Up to 48 weeks of daily applications and professional removal, as frequently as monthly, of the unattached, infected nail are considered the full treatment to achieve a clear or almost clear nail. Six months of therapy with professional removal of the unattached, infected nail may be required before initial improvement of symptoms is noticed.

Usual Adult Dose for Seborrheic Dermatitis

1% gel:
Apply to affected area twice a day for 4 weeks.

1% shampoo:
Wet hair and apply 1 teaspoon (5 mL) to scalp. Up to 2 teaspoons may be used for long hair. Lather and leave on hair and scalp for 3 minutes, then rinse off. Repeat twice weekly for 4 weeks, with at least 3 days between applications. Avoid contact with eyes.

Usual Adult Dose for Cutaneous Candidiasis

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Adult Dose for Tinea Cruris

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Adult Dose for Tinea Versicolor

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Adult Dose for Tinea Corporis

1% gel:
Apply to affected area twice a day for 4 weeks.

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Adult Dose for Tinea Pedis

1% gel:
Apply to affected area twice a day for 4 weeks.

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Pediatric Dose for Seborrheic Dermatitis

Greater than 16 years:
1% gel:
Apply to affected area twice a day for 4 weeks.

1% shampoo:
Wet hair and apply 1 teaspoon (5 mL) to scalp. Up to 2 teaspoons may be used for long hair. Lather and leave on hair and scalp for 3 minutes, then rinse off. Repeat twice weekly for 4 weeks, with at least 3 days between applications. Avoid contact with eyes.

Usual Pediatric Dose for Cutaneous Candidiasis

Greater than 10 years:
1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Pediatric Dose for Tinea Cruris

Greater than 10 years:
1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Pediatric Dose for Tinea Versicolor

Greater than 10 years:
1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Pediatric Dose for Tinea Corporis

Greater than 10 years:
1% gel:
Apply to affected area twice a day for 4 weeks.

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Usual Pediatric Dose for Tinea Pedis

Greater than 10 years:
1% gel:
Apply to affected area twice a day for 4 weeks.

1% cream, lotion, or suspension:
Apply to affected area twice a day for 2 weeks.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Patients should be advised to contact their caregiver if they experience increased irritation (redness, itching, burning, blistering, swelling, oozing).

Treatment should be discontinued and appropriate therapy initiated if signs of sensitivity or local irritation occur.

Contact with eyes and mucous membranes should be avoided.

Dialysis

Data not available

Other Comments

Clinical improvement with relief of pruritus and other symptoms usually occurs within the first week of treatment. If a patient shows no clinical improvement after four weeks of treatment, the diagnosis should be redetermined. Patients with tinea versicolor usually exhibit clinical and mycological clearing after 2 weeks of treatment.

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