Skip to main content

Calcium Disodium Versenate Disease Interactions

There are 3 disease interactions with Calcium Disodium Versenate (edetate calcium disodium).

Major

Calcium EDTA (applies to Calcium Disodium Versenate) hepatitis

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis

Edetate calcium disodium should not be given to patients with active hepatitis.

References

  1. "Product Information. Calcium Disodium Versenate (edetate calcium disodium)." 3M Pharmaceuticals
Major

Calcium EDTA (applies to Calcium Disodium Versenate) renal dysfunction

Major Potential Hazard, High plausibility. Applicable conditions: Dehydration

The use of calcium EDTA is contraindicated in patients with anuria and active renal disease. Dose-related nephrotoxicity (usually reversible) associated with EDTA has included dysuria, oliguria, proteinuria, large renal epithelial cells in urine, renal insufficiency/failure, and acute tubular necrosis. Impaired renal function decreases the elimination of EDTA and may increase its nephrotoxicity. Adequate hydration (avoid excess hydration in patients with lead encephalopathy) and established urine flow prior to initiation of EDTA therapy is necessary. Clinical monitoring of renal function and calcium, phosphorus, and zinc levels is recommended.

References

  1. "Product Information. Calcium Disodium Versenate (edetate calcium disodium)." 3M Pharmaceuticals
Moderate

EDTA (applies to Calcium Disodium Versenate) insulin/diabetes

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus

EDTA may chelate zinc present in exogenous insulin and alter glucose concentrations and insulin requirements in patients with diabetes. Insulin dosages may need to be adjusted in diabetic patients administered EDTA.

References

  1. "Product Information. Calcium Disodium Versenate (edetate calcium disodium)." 3M Pharmaceuticals
  2. "Product Information. Disotate (edetate disodium)." Abbott Pharmaceutical

Calcium Disodium Versenate drug interactions

There are 37 drug interactions with Calcium Disodium Versenate (edetate calcium disodium).

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer