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Tramadol for Restless Legs Syndrome User Reviews (Page 4)

Brand names: Tramadol Hydrochloride ER, ConZip Qdolo

Tramadol has an average rating of 8.8 out of 10 from a total of 122 reviews for the off-label treatment of Restless Legs Syndrome. 86% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Tramadol

  • Alask...
  • Taken for 5 to 10 years
  • December 21, 2019

"I’ve had RLS for over 40 years. Tried all the recommended meds most did not work, some caused augmentation. Was prescribed Tramadol about six years ago in the ER, and the immediate release forms. It’s getting to the point when several times a month it’s not working as effectively as before. I’m looking for another med I can take in addition to Tramadol. Is anyone else having this problem, and are any of you taking multiple drugs to relieve your RLS symptoms? Thank you!"

8 / 10
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  • Anonymous
  • September 2, 2010

"I have taken Tramadol as prescribed by my doctor for a little over 2 years. It works 100% for my restless legs syndrome. The only downside to this medication is the withdrawal symptoms when you stop. You have twice as bad the problem of restlessness than you had in the first place. The doctor gave me Clonidine and that really helped with the withdrawal problems."

9 / 10
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25 Report
  • Anonymous
  • May 30, 2010

"I have Restless Legs Syndrome and it has a major impact on my life. Tramadol (generic) has really helped my RLS. It takes quite a while to set in but then lasts for a whole day or more due to its long half-life. It does keep me up a little later than normal, but I feel much more relaxed and without the RLS at night. I think it is a good medicine when taken as prescribed and with regular check-ins with your doctor regarding dosing. If you have side effects, hang in there for a few days and they will mostly subside."

8 / 10
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Frequently asked questions

  • awake...
  • May 17, 2011

"I'm lying here wide awake at 3:45 am on my 2nd night of trying to wean myself off tramadol under my doctors orders. He gave me temazapam as a sleep aid and told me to go from 100 mg to 50 mg of tramadol plus 30 mg of temazapam. Last night was okay, woke up feeling pretty good, but tonight I am back to being miserable because of my restless legs syndrome. He's never had it, obviously. His concern is that I will require more as I go along. I've been on 100mg tramadol for about 6 months. I love that I can sleep, but I'm groggy during the day. If I don't sleep, I'm groggy as well. I prefer to sleep! This RLS has been lifelong, since 8 years old. Brothers and mother have it as well. My middle brother just started tramadol tonight. Will see what he thinks!"

10 / 10
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23 Report
  • KeithT
  • October 5, 2010

"I am prescribed Tramadol for chronic back pain. The fist time I took it, I finally felt "normal". I had occasionally had restless legs and cramps. However, after a back adjustment removed the back pain, I tried to get off the Tramadol and became VERY agitated, almost in a panic once, so withdrawal can be a problem. I understand tapering is the way to do it, but my back pain returned and I am still on about 150MG spread over 24hrs. Try the LOWEST dosage if you try it."

8 / 10
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Are you taking this medicine?

  • Anonymous
  • March 15, 2011

"Works great for restless legs and back pain, and agreed so what if you need to be on it forever. I need to be on Synthroid forever, and Premarin forever too. If it helps me sleep good at night so be it."

10 / 10
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23 Report
  • Hassan...
  • April 9, 2016

"I have RLS and my legs really hurts at night, even at days but not as much. my wifes mother Gave me a Tramadol that she use fore her back pain, i sleep like a baby, i fall a sleep really Quick and have a really nice sleep, when i dont take it i cant sleep at night. 100mg to 200mg will do it."

10 / 10
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More FAQ

  • Anonymous
  • June 30, 2011

Ultram (tramadol) "Tramadol has been very effective for my severe restless legs syndrome. However the body does seem to build tolerancce so you must increase dose from time to time. The withdrawal effects are quite severe. I found that a slow withdrawal helps ease the discomfort. I have also been on Neurontin in the past and had good results for several years but the effectiveness seems to lessen over time and increasing the dose did not help. "

7 / 10
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  • jeffh...
  • April 19, 2009

"Since starting Tramadol 2 years ago (300 mg daily), I've been symptom free from restless leg syndrome with no side effects. Prior to Tramadol, I experience acute pain in legs when inactive during the evenings. A sleep study also revealed moderate leg twitching during sleep which interfered with REM. I was prescribed Requip 4mg but had a couple of very bad reactions (sudden onset of acute sweating and nausea). I also take Tramadol for mild chronic back pain. Breakthrough pain can occur due to the relatively low strength of Tramadol compared to other prescription pain relievers. However, it's more accessible due to it being a non-narcotic, non-scheduled drug. "

10 / 10
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  • Babysaw
  • October 29, 2011

Ultram (tramadol) "I have had restless legs syndrome for about a year now. It drives me crazy. It is just in my left leg no where else. Dr gave me Requip and did nothing. I tried tramadol and although I still have a bit of tingling in my leg and foot, my leg seems more relaxed. I will say that the ONLY thing I have found to work right away and all day is Vicodin. My doctor told me that pain medicines are a treatment for restless legs syndrome. I'm hoping the tramadol is a winner so I can stop with the pain medicine."

7 / 10
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  • Anonymous
  • June 9, 2008

"I've used every medication possible to control Restless Leg Syndrome. At present I'm alternating between hydrocodone and tramadol. They both work fairly well to control the condition but I need to alternate back and forth between them."

9 / 10
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  • Me Re...
  • Taken for 2 to 5 years
  • November 22, 2022

"It's the only thing that eases it. Thank God the creator that my doctor is compassionate and helps me by understanding and believing me that I need it for medical issue. I have no side effects except continual fatigue"

10 / 10
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  • Theatre
  • Taken for 1 to 6 months
  • December 8, 2014

"I have had restless legs syndrome for over a decade varying from mild, moderate to quite severe at times. After being prescribed Prozac I found that it helped the depression but made the restless legs syndrome worse. After falling and cracking my ribs I was prescribed 100mg Tramadol twice daily. It was excellent for pain relief, RLS completely disappeared and I got a good night's sleep. I stopped the Tramadol after 2 weeks and experienced flu like withdrawal symptoms and RLS returned with a vengeance. Internet info is that Prozac can affect restless legs syndrome and taken with Tramadol can cause serotonin syndrome. I contacted doctor and requested lower dose Tramadol to wean myself off. I am still taking one 50mg at 4pm, any later and the RLS kicks in and is harder to control."

8 / 10
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  • laryd
  • Taken for 2 to 5 years
  • December 26, 2017

"I had severe RLS and have tried all of the RLS meds. They seemed to work for a little while. Horrible side effects. My research indicated the most effective treatment, opium, of course in this day and age would be impossible. So I read everything I could find on Tramadol, "an opiate" It seems that all who were prescribed it for pain found that their RLS miraculously disappeared. This happened with me also. It was prescribed after neck surgery. When I became convinced that it worked I told my Dr. outright that it worked and was the only thing that has, with no side effects. Prior to it being ok'd for RLS I do have another condition that is treatable Klippel Feil .I have a script of 300XR and 50mg."

10 / 10
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  • SKano
  • Taken for less than 1 month
  • August 3, 2019

"I had to chuckle when I read that Tramadol was used for RLS! I have had RLS since childhood. Was given Tramadol for pain after knee replacement surgery. In reading up on the Tramadol, I saw that it was used for RLS also. It didn’t do a thing for my RLS! I have read in other articles, that RLS may be the only observed symptom for some people with adult ADHD. Of course the other symptoms are there, but the person may not be aware of them. I have had the ADHD diagnosis for many years......just had never realized that RLS could be part of it! My doctor has prescribed a very low dose of Adderall to use for nighttime ADHD problems.......RLS being one of them. I have also found that drinking a cup of coffee helps with the RLS. I know this sound weird, but it helps!"

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  • ACC43...
  • Taken for 6 months to 1 year
  • March 5, 2023

"I was in misery for years trying to manage my RLS. Compression socks, Magnesium Spray, Lyrica, Gabapentin, stretches, etc. Nothing worked. The sleep deprivation was worse than when my newborn daughter had colic for 4 months. Finally, I went to an awesome neurologist who worked with me on options. LSS, I’m taking Horizant at 5 pm and I take 1/2 capsule of 50 mg Tramadol a nite before bed and I’m finally getting consistent sleep. I’m not sleeping as soundly or as long as I’d prefer though it’s improved to the point where at least I’m having some consistent sleep and I’m no longer losing my mind."

9 / 10
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  • RLS...
  • June 22, 2016

"tramadol never worked for me and i have severe RLS. i have had RLS since i was 8 years of age and now am 36. I do have a high tolerance to many medications or they are only effective for a short period of time before i need an increase of dose. However i never found tramadol at any dose to help."

2 / 10
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  • lorina
  • January 27, 2010

Ultram (tramadol) "My very serious problem is my legs. I do always have cramps every time I stand for a longer hours and it really affects my work, after I take this medicine.,I can say that its a miracle! it works for me. I love it!"

9 / 10
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  • Patsi
  • Taken for 10 years or more
  • July 10, 2023

"Thank God above for Tramadol! I was nervous when they decided it was a controlled substance, but my doctor understands what I went through before. 100 mg at 3pm and 100 mg at 9pm. I can't even relax and watch a movie without it, my RLS and RAS are so bad! Never have taken more or less for many many years!"

10 / 10
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  • KiwiKev
  • March 1, 2010

"I got Restless Leg Syndrome and severe lower back pain due to a horrific car accident. Tramodol made me sick so I had to stop. I have tried all the medicines you can think off, even the ones for epilepsy and anti-seizure drugs. The only thing that gives me relief from the RLS and chronic back pain is slow release morphine. Have now been on it since 1991. If people and doctors knew what living with the RLS and chronic pain is like, they would never doubt or disbelieve you again. Imagine not being able to sit or sleep or lie still anywhere or anytime, forget sleeping at nite, until you are just so physically exhausted and drained from having to move your legs constantly 24hrs a day. It's awful."

1 / 10
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  • Hpano
  • Taken for less than 1 month
  • October 8, 2019

"I didn’t realize the pain in my legs was RLS. I’ve had this horrible pain as long as I can remember. I would be in such pain at night my Dad would have to rub my legs until I fell asleep. Back then everyone said it’s just growing pains well here I am at 2:36am in such pain. I’m wondering if anyone has more pain in one leg and if so does it go from your knee all the to the bottom of your foot? I asked Siri what can I take for this horrible pain in my legs and this popped up. I do have some tramadol left over from a previous incident so here goes. Also mine I very weather related. When there is a shift in the weather no matter what type I know I’m in for severe pain;(."

5 / 10
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  • korpu...
  • Taken for less than 1 month
  • September 25, 2015

"If I could give it a negative 10, I would. I took a 50mg pill about 1 1/2 hours ago and still NOT WORKING. I can't have another one for 8 hours, and I am afraid to take anything else at this time. I am calling doc tomorrow for something else."

1 / 10
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  • Septu
  • Taken for 5 to 10 years
  • March 15, 2021

"I am a 54 year old male and I have suffered from RSL since I was in my late 20's. Over the years I have tried various medications as well as every type of alternative therapy I came across. Most of the usual medications had unfortunate side effects including altering my mood and personality (according to my wife) and none of the alternative therapies had a noticeable effect on my RSL. I was given Tramadol for pain and when I came out of hospital for an unrelated condition and was surprised to find that it also completely removed all my RSL symptoms. I have now been on Tramadol (50mg) just before bed time for over 8 years now and last year managed to reduce the dose to 25mg (liquid preparation) which still amazingly gives me a good night sleep. Outside of constipation I have no other noticeable side effects from Tramadol. I would highly recommend anyone try Tramadol (maybe start with 25mg). It has truly been a life saver for me."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • December 30, 2023

"I have RLS with strong pain and cramps in legs and arms. I take 2 sifrol every evening at 17:30. This suppresses like 80% of the pain. The remaining pain is still uncomfortable in the evening/night. Three years ago, I took tramadol for a blocked neck. To my big surprise, it also suppressed the remaining pain from RLS. Since then, I can spend my evenings again without pain and discomfort, and watch TV in a relaxed way."

9 / 10
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  • Cristi
  • Taken for 2 to 5 years
  • January 11, 2022

"If it wasn’t for tramadol I would have possibly committed suicide by now because of my restless legs syndrome! !! I have tried everything, gabapentin, pramaprexole…etc,,, but tramadol helps me. The only thing that has helped my legs stop going crazy! Without the horrible side effects of these other medications. They make me so nauseous and sick. But tramadol makes me feel fine. I can sleep and no side effects!! So why can’t this be a prescription?!!!"

10 / 10
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4 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Restless Legs Syndrome

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Symptoms and treatments

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