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Zanaflex for Cluster Headaches User Reviews

Zanaflex has an average rating of 8.0 out of 10 from a total of 6 reviews for the off-label treatment of Cluster Headaches. 83% of reviewers reported a positive experience, while 17% reported a negative experience.

Zanaflex rating summary

8.0/10 average rating

6 ratings from 7 user reviews.

Compare all 27 medications used in the treatment of Cluster Headaches.

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  • Oodle...
  • Taken for 1 to 6 months
  • March 25, 2017

"Absolutely love this medication. I suffer from chronic migraines and daily headaches. I take 4mg of Zanaflex at breakfast, 2mg at lunch, and 4mg at bedtime. I'll take 6mg during a migraine attack and it helps tremendously with the pain, helps me sleep, and actually helps with the nausea. Zanaflex made me very drowsy at first and still does taken at doses of 4mg. Overall, incredibly helpful drug!"

9 / 10
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  • rrdul...
  • August 13, 2009

"I take Zanaflex for chronic tension/cluster headaches, I was suffering daily with tension headaches and I also get migraines. This drug has been a life saver for me. I have tried everything. Imitrex is still good for the migraine, when one will slip through and you are not able to take this during during the day. This medicine will cause you to sleep. I take it just before bed. But I have actually had days without a headache and before this medication that was not possible. I was truly waking up and going to bed each day with a horrible a headache and as a high school teacher, that made my job a lot harder. I am still on Topamax to keep the migraines from breaking through. I am hoping when I go through menopause, all this will go away."

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  • Kaety
  • May 28, 2009

"This works great. I take it for back spasm but also for cluster headaches. I had a stroke several years ago at age 28 years, so I am limited in what medicines I can take due to my medical history. My doctor has me take more than I need for back spasm/pain. I was warned it would make me sleepy and usually does, but in that time my headache/pain goes away almost completely. It is wonderful, especially since it is not a controlled substance. I'd rather take this for both conditions than the 100mg Demerol every 4 hours I was on for several years. Not only don't I miss the injections, but since it does not have the side effects and addiction I can do more since I can think more clearly and function more."

10 / 10
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105 Report

Frequently asked questions

  • Anonymous
  • March 22, 2012

"I suffer from migraines and also have difficulty falling and staying asleep. Following. A sleep study my doctor put me on Zanaflex to help me fall asleep faster and reduced random leg movements during the night. I took for it about a month and it really helped me sleep although I did have a groggy feeling in the morning that was hard to shake off. However, it aggravated my migraines so that instead of getting them 2 or 3 times a year, I got a migraine every week during the month I was taking Zanaflex, so unfortunately I had to stop taking it."

2 / 10
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  • Anony...
  • April 22, 2017

"I have suffered from daily migraines for over 20 years. Have tried many medicines through the years and this has really decreased the number I have. Went from daily to once every couple of weeks or so. I take 4 mg at bedtime every night and immitrex when I feel one coming on."

9 / 10
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56 Report

Are you taking this medicine?

  • Anonymous
  • April 20, 2010

"I have been taking Zanaflex and Desipramine for my daily headaches for about 1 1/2 years. They have greatly decreased the number of headaches and I am very thankful for the relief. I do experience dry mouth and frequent urination but I can live with that. Much easier than the horrible headaches I was experiencing daily."

8 / 10
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  • KRD
  • Taken for 1 to 2 years
  • November 8, 2022

"It knocks me out but it’s the only thing that works when I have a migraine and triptans aren’t working. I use it as my “Big Gun” when everything else fails and I’m not planning to drive any time to on after taking it. I also use it for cervical and thoracic radiculopathy when flexeril and meloxicam aren’t enough. Gives me dry mouth and constipation but I take a stool softener and a big glass of water with it."

10 / 10
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6 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Cluster Headaches

Symptoms and treatments

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