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Sulfasalazine User Reviews & Ratings (Page 5)

Brand names: Azulfidine, Azulfidine EN-tabs

Sulfasalazine has an average rating of 5.9 out of 10 from a total of 182 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Sulfasalazine

  • Papa
  • Taken for 6 months to 1 year
  • April 30, 2023

For Psoriatic Arthritis "Since I’ve been taking sulfasalazine I don’t wake up with my finger joints nearly as swollen and I have more flexibility. My joints don’t ache as bad as they did before taking it. I haven’t had any side effects and I’ve been taking it for several months. I take two tablets in the morning and two at night."

9 / 10
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  • Top...
  • Taken for 1 to 2 years
  • August 27, 2019

"The first year sulfasalazine felt like a miracle cure for my Ankylosing Spondylitis absolutely no back hip and knee pains at all Now I’m getting a bout or two knee pains that come and go although thankfully still no Back and Hip pains What is happening now and quite often stomach problems including indigestion and reflux My Doctors seem to completely ignore my case possibly because I’m over seen by London Euston hospital and getting to talk to anyone at the hospital is all but impossible If you are in early stage of disease this drug will really help"

10 / 10
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  • Keith
  • Taken for 5 to 10 years
  • March 25, 2023

For Rheumatoid Arthritis "I've taken this drug for at least 5 years, and it controls the swelling and inflammation in my hands and arms. I'm one of the lucky ones that has little or no pain from the disease. I've tried other RA drugs that haven't worked. I've had no side effects with the exception of loose bowel movement."

10 / 10
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  • Wsws
  • Taken for less than 1 month
  • January 10, 2022

Sulfazine (sulfasalazine) for Rheumatoid Arthritis "Taking for 3 weeks. Such severe headaches ended up in ER. Doesn’t matter if it helps joint pain if the headache is continuous and unbearable. This is a vile drug and would not recommend it to anyone."

1 / 10
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  • Lucky
  • Taken for 1 to 2 years
  • February 27, 2023

For Rheumatoid Arthritis "Diagnosed with Polymyalgia Rheumatica. Symptoms were so severe that I could barely get out of bed. Had to take heavy dose of Prednisone for many months to help counter inflammation until the Sulfasazine kicked in. Took several more months but now symptom free. Have to have blood monitored every three months. Has been a life savior. No side effects other than bleeding gums. Taking 2000 mg daily."

10 / 10
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  • Jan...
  • Taken for 1 to 6 months
  • January 31, 2024

For Rheumatoid Arthritis "I've been taking Sulfasalazine for six months and this is the first drug that's really worked. That said, I'm suddenly getting a hive-like rash and bruising down my arms. I hate to think it's this drug, but think it likely is."

10 / 10
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  • Horti...
  • Taken for 10 years or more
  • May 18, 2021

For Rheumatoid Arthritis "I have had RA for at least 25 years. I have tried many RA drugs with not much help, both injection and pill. I have also been on sulfasalazine for a number of years now. It has helped to some extent, nothing overwhelming. But better than any of the other drugs. It has helped with IBS which I have as well. Just before Covid hit I was about to try yet another drug that would lower my immune system, to fight the RA, but held off. Now that I am vaccinated and the Covid numbers are falling I am going to try another drug. But during this covid year sulfasalazine did keep RA somewhat under control with no side effects."

6 / 10
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  • person
  • Taken for 1 to 6 months
  • March 27, 2023

For Psoriatic Arthritis "28F, diagnosed with Psoriatic Arthritis one year ago. I had very painful fingers and knees, and taking weekly 25mg methotrexate injections helped, but did not fully eradicate the pain or help me regain function. After a bout of uveitis, and a new onset migraine with aura, sulfasalazine got added (2500mg, titrated up to 500mg a week). Although it took a while to work, it improved my condition dramatically. It feels almost back to normal pain and function wise and general fatigue levels have improved somewhat. The abdominal side effects are the ones that still bother me, with bouts of nausea and painful bloating almost daily. I was advised it may take a few more months to improve, but honestly, I feel I can live with that as long as I get to keep the benefits of it."

8 / 10
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  • cmurf
  • Taken for 1 to 6 months
  • May 31, 2018

For Psoriatic Arthritis "I am starting Sulfasalazine for the second time as the first time I ended up coming down with the flu a couple of times so decided to wait. My symptoms have been worse so just started it again. I am on my last day of two pills in the morning and one in the evening. No real bad side effects other than increased joint aching, especially in hip. I had a lot of trouble sleeping last night as I just couldn't get comfortable at all. I'm supposed to increase gradually up to three pills in the morning and three at night. I will have to see how it goes though. I am not really patient when it comes to side effects."

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  • Aussie...
  • Taken for 1 to 6 months
  • February 5, 2017

For Psoriatic Arthritis "Trialled this medicine for Psoriatic arthritis for approx 6 months in combination with Methotrexate and Hydroxychloroquinine. While no major side effects there was no clinical efficacy either so therapy was discontinued."

1 / 10
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  • Nunny...
  • Taken for 2 to 5 years
  • December 1, 2017

For Rheumatoid Arthritis "Been on six a day lot of help. don’t feel much better after 2 years on them they don’t do enough for you there is drug called the liquid gold I have spoke to people they are normal again no aches pains stiffness etc. But only the queen and Simon Cowell and rich will get them I been told it’s costs £36000 per year for years course of tablets !"

3 / 10
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  • Jinny
  • Taken for 1 to 2 years
  • November 16, 2023

For Rheumatoid Arthritis "This drug has worked incredibly well for my rheumatoid arthritis. It really changed my life. However, I have had terrible side effects: chronic insomnia, headaches every day, a feeling of having a cold or flu all the time. I have kept on taking it because without it all my symptoms come back and I cannot function properly, but the side effects have greatly affected my quality of life."

7 / 10
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  • DrG
  • Taken for 1 to 2 years
  • August 8, 2017

For Rheumatoid Arthritis "Update from June. My husband has been improving in terms of his Anaemia of Chronic disease on Prednisone 15mg daily. However still on 2 gms of Sulfasalazine he has had Pleuritis for two months and now has Conjunctivitis and .? Scleritis. All of which are listed as side effects of Sulfasalazine. These are his only symptoms associated with RA. While reluctant to reduce the Sulfasalazine we will do so. We increased the Minocycline to 200mg alt days. a few days ago."

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  • Anonymous
  • Taken for 1 to 6 months
  • March 16, 2018

"Have been taking Sulfasalazine for about two months for spondyloarthritis. Not only has it made no difference to joint/muscle pain, but it has severely worsened my fatigue. I feel like I have flu constantly. Also causing terrible thirst. Hoping things will improve with time, but so far not at all encouraging."

1 / 10
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  • GUblues
  • November 26, 2017

For Ulcerative Colitis "I was on Lialda and in remission for over two years, unfortunately insurance doesn’t cover it anymore. No flares, but I do have canker sores all over my mouth, swollen lips and red splotches in my face that itch. I had to stop and now waiting for another prescription."

4 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • October 9, 2022

For Crohn's Disease "Diagnosed with Crohn's Disease 11 months ago. Was on budesonide, then taper off and put on sulfazalne 6 pills daily 3000 mg total. Sulfazaline worsened knee down pain both legs. Also experienced brain fog, anxiety and depression. Have been off meds for 3 weeks now and feel clear headed, happier, no depression, leg pain seems so much better. Do have insomnia now. Stopped medicine as new doctor feels I was misdiagnosed. Will find out later this week."

3 / 10
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  • Lou
  • Taken for 1 to 6 months
  • August 31, 2021

For Rheumatoid Arthritis "After 8 weeks taking the drug increasing from 500mg to 2000mg dosage, some improvements with RA but suffering with depression and anxiety and unable to continue living like this. I would rather have RA, waiting for consultant to advise if I can try different treatment."

2 / 10
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  • Charles
  • Taken for 5 to 10 years
  • August 30, 2023

For Ulcerative Colitis, Maintenance "At present, I am taking one tablet a day to keep my U.C. under control. I have had no unexpected side effects. This was an alternative to other drugs because of the vast price difference between Sulfasalazine and the other choices. Being on Medicare, I have to watch the costs of medications."

9 / 10
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  • overp...
  • Taken for 1 to 6 months
  • August 27, 2023

For Psoriatic Arthritis "Was started on sulfasalazine after a virus caused a flare of what the rheumatologist thought was PsA & fibromyalgia. Dr later determined my PsA wasn't active but still continued the sulfasalazine. The dose was 1000mg twice a day. I believe it caused me headaches & nausea at the start. Dr encourages me to continue the medication. I have stopped & restarted the medication with his 'advice' but still don't think it is doing anything for me."

5 / 10
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  • Anonymous
  • Taken for 10 years or more
  • July 3, 2017

For Crohn's Disease, Maintenance "I was on sulfasalazine for 25 years until my kidney function decreased, and I had bone marrow suppression. In other words, I became pretty ill. I already had third stage kidney disease from another medication, bipolar. I take Topamax for the migraines.I have gastroparesis and take 5 other medications. I originally started with acute crohn's olitis but have been in remission since taking prednisone & then sulfasalazine"

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  • MrsM
  • Taken for 2 to 5 years
  • July 17, 2023

For Rheumatoid Arthritis "I have been taking Sulfasalazine for several years and had to increase dosage (tripled) over that time period. It works fairly well for pain, but the heat sensitivity/intolerance to sun is horrible in the summertime. I also get a red rash on my arms from it, worse in the summer. I become a prisoner in my home. I will probably go back to Leflunamide, however, that causes hair loss, so I'm not sure what I'll do just yet. Sulfasalazine is fairly effective, but I had to give it a lower rating due to the side effects."

6 / 10
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  • Paint...
  • Taken for 1 to 6 months
  • May 28, 2023

For Ulcerative Colitis, Active "Went on Sulfasalazine for my UC after having allergic reactions to Mesalamine. Started with one pill twice a day to see how I’d tolerate it, and got up to two pills twice a day. This never helped my symptoms, never eased the bleeding, and after about 2 weeks on the full dose, I developed a fever, body aches, and felt extremely fatigued. No other symptoms. After three days I called my doctor who said to stop the drug immediately. I didn’t take my evening pills that night and my fever started to come down that evening and the next day my fever was almost normal. Two days later I felt fantastic (now off the drug). I’m using Bromelain supplements and fresh pineapple instead; works so far with no side effects."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 4, 2023

For Rheumatoid Arthritis "I am noticing that I'm eating less since I started the 2nd dose which I find quite interesting and having questions if I should be concerned. The RA has slowed down kind of but still having issues with it on my left hand."

9 / 10
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  • Pusheen
  • Taken for 6 months to 1 year
  • December 11, 2016

For Juvenile Rheumatoid Arthritis "Sulfasalazine initially caused extreme headaches upon waking, extra strength acetametaphine worked for those. It took months to begin to work and I eventually got to 4 pills per day. It took an extra six months for it to work well. I still have low grade inflammation but at least I am not miserable anymore, can sleep through the night and get up fairly well. So it did work but for me it took a super long time to do so. My CRP dropped to normal (2 from 16.5) well before I felt close to normal."

7 / 10
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  • shed...
  • Taken for less than 1 month
  • February 26, 2023

For Rheumatoid Arthritis "It worked well for my joint pain and discomfort from Rheumatoid arthritis. I was taking 500mg of it 2 times a day, but not long after taking it I began to break out, first itching, biting feeling then, within a week 3/4 of my body was covered in flaky skin like a fish scale."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.