User Reviews for Sulfasalazine

Also known as: Azulfidine, Azulfidine EN-tabs, Sulfazine

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Sulfasalazine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Inflammatory Bowel Disease 2 reviews 73 medications
   
10
Crohn's Disease 2 reviews 66 medications
   
9.7
Crohn's Disease, Maintenance 0 reviews 23 medications
   
8.0
Rheumatoid Arthritis 9 reviews 362 medications
   
7.4
Psoriatic Arthritis 5 reviews 73 medications
   
5.6
Juvenile Rheumatoid Arthritis 1 reviews 113 medications
   
5.0
Ulcerative Colitis 6 reviews 74 medications
   
4.8
Crohn's Disease, Acute 1 reviews 14 medications
   
4.5
Ulcerative Colitis, Maintenance 0 reviews 15 medications
   
3.0
Alopecia 0 reviews 29 medications Not rated - Be the first
Lymphocytic Colitis 0 reviews 30 medications Not rated - Be the first
Ulcerative Colitis, Active 0 reviews 69 medications Not rated - Be the first
Uveitis 0 reviews 95 medications Not rated - Be the first
Summary of Sulfasalazine reviews 26 reviews 6.6

Reviews for Sulfasalazine

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Review by beccacamden (taken for 2 to 5 years):

User Rating:  
   
5.0

Azulfidine (sulfasalazine) for Juvenile Rheumatoid Arthritis: Worked really well when I was younger. Now 30 years later, it isn't as effective, and it causes stomach upset. Even when taken with food.

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August 1, 2014 7:18 PM

Review by Anonymous (taken for 6 months to 1 year):

User Rating:  
   
10

For Crohn's Disease: Severe flare put me in the hospital. Have had no problems in 9 months of taking sulfasalazine went against doctors advice choose this over stronger medication. All labs have been good since. Also got a new doctor!

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July 13, 2014 6:43 PM

Review by Jbm61:

User Rating:  
   
10

For Psoriatic Arthritis: After being on methotrexate and Humira I experienced no relief as well as a SEVERE LIFE THREATENING episode called Ludwigs Angina, ended up in a coma for 4 days, and was told if I had waited 1/2 hr longer to go to ER, I probably wouldn't have survived! I swore off all arthritic medicines for a year, except for pain medicines. Rheumatologist understood, and after a year suggested we start back very passively as opposed to aggressively to treatment. She suggested SSZ (sulfasalazine) and I reluctantly agreed. I was told it could take up to 3-4 months before I would see any improvement. Within 3 weeks I felt like a new person, I've been on it for a year and feel wonderful!

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June 25, 2014 6:38 AM

Review by SGM:

User Rating:  
   
6.0

For Rheumatoid Arthritis: Rheumatoid arthritis since 1994, pretty severe case. Had to stop taking Humira and methotrexate due to repeated bouts with pneumonia and lung damage. Currently on sulfasalazine, Plaquenil and prednisone. Occasional flares but things are basically back under control.

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May 6, 2014 9:41 AM

Review by mpsprowl (taken for 1 to 6 months):

User Rating:  
   
1.0

For Ulcerative Colitis: The only positives I have personally is no side effects and less expensive than other medications for ulcerative colitis.

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April 28, 2014 11:30 AM

Review by sarahyue:

User Rating:  
   
8.0

Sulfazine (sulfasalazine) for Ulcerative Colitis: I have been taking this medication for a while now, along with Azathioprine and Prednisone. Just today I stopped the Prednisone, after decreasing by a half each week. I experienced some remission of the Prednisone after I was at 2 and 1/2 pills, and bumped it back up to 5. I haven't experienced any bad side effects of the Sulfazine, and my only complaint is that it is really chalky. I am 13, and was diagnosed with Ulcerative Colitis almost a year ago.

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April 7, 2014 12:03 AM

Review by Washington State (taken for 1 to 6 months):

User Rating:  
   
10

Sulfazine (sulfasalazine) for Inflammatory Bowel Disease: In remission all labs and inflamatory markers normal. No side effects other than a headache once in a while.

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March 27, 2014 4:20 PM

Review by Dbestdeb:

User Rating:  
   
7.0

For Rheumatoid Arthritis: Have been on sulfasalazine for a year since being diagnosed with rheumatoid arthritis. I am grateful to have it since other medicines aren't an option for me due to unexplained elevated liver enzymes. It has helped the pain of rheumatoid arthritis quite a lot and my inflammation has gone down. I just wish it addressed the fatigue.

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March 7, 2014 10:31 AM

Review by MarkMan (taken for 10 years or more):

User Rating:  
   
10

For Rheumatoid Arthritis: I have been taking sulfasalazine for 19 years, the age of my son. As a baby I could not lift him, my wrists were too painful. My rheumatoid arthritis was in 15 joints, symmetrical, etc. I was on the Dutch COBRA study, combining sulfasalazine, methotrexate and prednisone, except I was in the placebo group getting only sulfasalazine. It kicked in after 6 weeks and do far has worked well. Some issues with my left foot started a year ago, but it doesn't stop me hiking in The Alps for a week.

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March 3, 2014 1:10 AM

Review by vaibhavr:

User Rating:  
   
9.0

For Rheumatoid Arthritis: I have been on it since 2009 due to severe back pain. I was told I have ankylosing spondilitis, a disease which affects joints. But this medicine improved my condition up to the point that I can lead a normal life again.

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February 3, 2014 12:55 PM

Review by Jelly B (taken for 1 to 6 months):

User Rating:  
   
2.0

For Psoriatic Arthritis: I slowly increased the dose weekly. I was ok on 2 a day but once increased to 3 my eyesight got a little worse. I reduced them for while then slowly up to 4 a day. The nausea was terrible I also felt really ill and very tired but didn't know why. Had to take time off work I felt so bad. Lowered dose to 2 again and was better but once I tried to increase it again the nausea and ill feelings came back. Stopped them and eventually felt better. Didn't realise just how bad they had affected me until I was back to normal again!

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January 12, 2014 6:38 PM

Review by eric017:

User Rating:  
   
10

For Crohn's Disease: I tried Lialda, Pentasa, and a few other medicines for my moderate Crohn's Disease and they all made it worse. I tried Sulfasalazine and I am symptom free as long as I don't forget to take any doses. If I miss a dosage I may have some loose stool but after I go back to taking it I once again am symptom free.

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May 24, 2013 1:40 AM

Review by Lora S. (taken for 1 to 2 years):

User Rating:  
   
10

For Psoriatic Arthritis: I LOVE THIS MEDICINE! I had tried many medicines before this including methotrexate which was HORRIBLE-they all made me so ill. I only had loose stools at the start of treatment as a side effect, no others. I take it alone, without NSAIDs and it manages all my pain and swelling like a champ. I have had no flares and I take 2 in the morning and 2 in the evening. My hair also stopped falling out after the 1st 2 months of taking it. It literally changed my life without shutting down my immune system. I could not be happier.

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May 15, 2013 4:44 AM

Review by RTRAVER (taken for 5 to 10 years):

User Rating:  
   
10

For Inflammatory Bowel Disease: My constant infections from Mycoplasma infections are a thing of the past. This medicine has kept intestinal leakage and polyps from recurring, keeps the blood in my urine to a minimum and constant kidney infections from recurring.

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January 21, 2013 12:12 PM

Review by Anonymous (taken for less than 1 month):

User Rating:  
   
1.0

Sulfazine (sulfasalazine) for Ulcerative Colitis: Upon taking sulfasalazine I experienced a severe headache, dizziness, bruising on my feet and legs, chills, blood shot eyes, pain in my joints, hives and swelling in my face and neck. The headache became so bad I could not get out of bed.

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August 25, 2012 4:18 AM

Review by tocha23 (taken for 2 to 5 years):

User Rating:  
   
5.0

For Psoriatic Arthritis: I too am using sulfasalazine for psoriatic arthritis and it has helped somewhat and I too have ringing in my ears. Suffice to say it has helped so I do recommend it.

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August 7, 2012 4:01 PM

Review by Anonymous:

User Rating:  
   
7.0

For Rheumatoid Arthritis: I've taken sulfasalazine for four months (1000 MG twice per day). It took at least six weeks to become effective, but combined with Etodolac, an anti-inflammatory, I have had good success with controlling a mono-arthritic knee that had been diagnosed as rheumatoid arthritis after almost 20 years of problems, various surgeries, etc. I worry about side-effects, but the pain and extreme swelling is controlled after many years.

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May 16, 2012 9:36 AM

Review by Anonymous:

User Rating:  
   
1.0

Sulfazine (sulfasalazine) for Crohn's Disease, Acute: This was the first medicine tried on me - I have (had) rheumatoid arthritis together with Crohns. Sulfazine did not help.

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April 4, 2012 10:05 AM

Review by Anonymous:

User Rating:  
   
1.0

For Psoriatic Arthritis: I never got to the full dosage of 2 pills twice a day. I was slowly increasing the dosage from one pill once to one pill once... that's as far as I got. The side effects were horrible. My mother, a breast cancer survivor, likened my side effects to chemo. My mind couldn't focus. I couldn't sleep, yet I was always drowsy. I always noticed that the side effects would ease about 6 hours after taking, then would show 30 min after taking. I finally gave up, and changed meds.

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February 29, 2012 3:36 AM

Review by Susanne35Cat:

User Rating:  
   
5.0

Sulfazine (sulfasalazine) for Rheumatoid Arthritis: I have Rheumatoid Arthritis and have been using Sulfasalazine for the last 4 years as an "add-on" to methotrexate. I take the maximum dose, but must confess that I can only see a minimal reduction of pain using this medicine.

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July 6, 2011 9:28 PM

Review by thetwoofus:

User Rating:  
   
9.0

For Rheumatoid Arthritis: Diagnosed with rheumatoid arthritis 18 months ago, been on sulfasalazine all time. First 2 months felt sick and headachey, but okay since. Found ringing in ears relieved by having high pillows, i.e. two good ones and a very soft lesser one. Visit Rheumatologist every 6 months, with blood tests every 3 months. Carpel tunnel was very bad prior to taking sulfasalazine. Much better now; keeping well.

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June 25, 2011 8:11 PM

Review by Anonymous:

User Rating:  
   
8.0

For Ulcerative Colitis: This has worked really well to maintain my symptoms and no real side effects.

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April 19, 2011 8:35 PM

Review by Anonymous:

User Rating:  
   
2.0

Sulfazine (sulfasalazine) for Ulcerative Colitis: Had terrible allergic reaction to this medicine, within a week of taking it. Felt terrible itching inside out.

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January 27, 2011 4:43 PM

Review by Anonymous:

User Rating:  
   
9.0

Sulfazine (sulfasalazine) for Rheumatoid Arthritis: Been on sulfasalazine for 3 years, for me the first 2 weeks were hard on the stomach. Felt like I was going to vomit all the time but never did, it was slow to have the effect maybe a month, but after that it has been good. Still get flare up the odd time. It is inexpensive compared to the other medications.

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October 24, 2010 3:27 PM

Review by karenbuff:

User Rating:  
   
4.0

Sulfazine (sulfasalazine) for Rheumatoid Arthritis: I have had a small improvement with sulfazine, but unfortunately I started having severe ringing in the ears after 6 months, also it gave me pain in my achilles tendon and calves at night. Keep in mind that I had the pain side effect also with cholestrol medications, but not the ringing in the ears.

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April 11, 2010 11:17 PM

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