Sulfasalazine delayed-release tabletsPronunciation
Generic Name: sulfasalazine (SUL-fa-SAL-a-zeen)
Brand Name: Azulfidine EN-tabs
Sulfasalazine delayed-release tablets is used for:
Treating ulcerative colitis, rheumatoid arthritis, or polyarticular-course juvenile rheumatoid arthritis in certain patients. It may be used along with other medicines. It is also used to increase the time between attacks of ulcerative colitis. It may also be used for other conditions as determined by your doctor.
Sulfasalazine delayed-release tablets is a salicylate. It decreases inflammation. Exactly how it works to treat ulcerative colitis is not known.
Do NOT use sulfasalazine delayed-release tablets if:
- you are allergic to any ingredient in sulfasalazine delayed-release tablets or to a salicylate (eg, aspirin) or a sulfonamide (eg, sulfisoxazole)
- you have the blood disorder porphyria or a stomach, bowel, or urinary tract blockage
- you have folate deficiency anemia
- the patient has systemic-course juvenile rheumatoid arthritis
Contact your doctor or health care provider right away if any of these apply to you.
Before using sulfasalazine delayed-release tablets:
Some medical conditions may interact with sulfasalazine delayed-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney problems, asthma, severe allergies, blood problems (eg, anemia, low white blood cell levels), or rheumatoid arthritis
- if you have glucose-6-phosphate dehydrogenase deficiency
- if you have an infection (eg, strep throat)
Some MEDICINES MAY INTERACT with sulfasalazine delayed-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin) or methotrexate because the risk of their side effects may be increased by sulfasalazine delayed-release tablets
- Beta-blockers (eg, propranolol), digoxin, or folic acid because their effectiveness may be decreased by sulfasalazine delayed-release tablets
- Methenamine because the risk of crystals in the urine is increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if sulfasalazine delayed-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use sulfasalazine delayed-release tablets:
Use sulfasalazine delayed-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take sulfasalazine delayed-release tablets by mouth after meals.
- Take sulfasalazine delayed-release tablets with a full glass of water (8 oz/240 mL).
- Swallow sulfasalazine delayed-release tablets whole. Do not break, crush, or chew before swallowing.
- Drinking extra fluids while you are taking sulfasalazine delayed-release tablets is recommended. Check with your doctor for instructions.
- Take sulfasalazine delayed-release tablets on a regular schedule to get the most benefit from it.
- Continue to take sulfasalazine delayed-release tablets even if you feel well. Do not miss any doses.
- If you miss a dose of sulfasalazine delayed-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use sulfasalazine delayed-release tablets.
Important safety information:
- Sulfasalazine delayed-release tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use sulfasalazine delayed-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Sulfasalazine delayed-release tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to sulfasalazine delayed-release tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Sulfasalazine delayed-release tablets may discolor the urine or skin an orange-yellow color. This is normal and not a cause for concern.
- Contact your doctor if you develop sore throat, fever, unusually pale skin, dark urine, pale stools, persistent stomach pain or loss of appetite, yellowing of the skin or eyes, or unusual bruising or bleeding. Contact your doctor if you have yellowing of the skin along with dark urine, pale stools, or persistent stomach pain or loss of appetite. These could be signs of a serious side effect.
- If you see the tablet in your stool, contact your doctor right away.
- Some men taking sulfasalazine delayed-release tablets have developed a decreased number of sperm and infertility. These effects usually went away after sulfasalazine delayed-release tablets was stopped. Discuss any questions or concerns with your doctor.
- Lab tests, including liver function, kidney function, complete blood cell counts, or urine tests, may be performed while you use sulfasalazine delayed-release tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use sulfasalazine delayed-release tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- Sulfasalazine delayed-release tablets should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
- Use sulfasalazine delayed-release tablets with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using sulfasalazine delayed-release tablets while you are pregnant. Sulfasalazine delayed-release tablets is found in breast milk. If you are or will be breast-feeding while you use sulfasalazine delayed-release tablets, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of sulfasalazine delayed-release tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; headache; loss of appetite; mild stomach upset or pain; nausea; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; bluish discoloration of the skin or nails; chest pain; dark urine; decreased urination; fever, chills, or sore throat; hearing loss; mental or mood changes; muscle pain; numbness or tingling in the fingers or toes; pale stools; persistent loss of appetite; pinpoint bruises; red, swollen, peeling, or blistered skin; seizures; severe or persistent dizziness, drowsiness, headache, or trouble sleeping; severe or persistent stomach pain; shortness of breath; trouble walking; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; yellowing of the eyes; yellowing of the skin along with dark urine, pale stools, or persistent loss of appetite.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include seizures; severe stomach pain, nausea, or vomiting; unusual or severe drowsiness.Proper storage of sulfasalazine delayed-release tablets:
Store sulfasalazine delayed-release tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep sulfasalazine delayed-release tablets out of the reach of children and away from pets.
- If you have any questions about sulfasalazine delayed-release tablets, please talk with your doctor, pharmacist, or other health care provider.
- Sulfasalazine delayed-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take sulfasalazine delayed-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about sulfasalazine delayed-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to sulfasalazine delayed-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using sulfasalazine delayed-release tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.