The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
The Euflexxa provides relief for me for the pain of bone on bone in both knees. Originally, the relief would last for a year, now it's down to about nine months. I have extreme pain upon receiving the injections. I'm very interested to see that no one else seems to have this. My MD/PA ices the knee first and uses a topical spray, but the actual injecting of the Euflexxa causes me a lot of pain. Yesterday, the PA kept telling me to breathe. She was afraid I was going to pass out. The first shot of the series of three is always the worst, so I'm hoping next week's injections won't be so bad. This is probably my fourth time to have these shots.
I'm 61. Late last year, I began having very painful osteoarthritis in both knees. Dr. said I'm nowhere near bone on bone, but I could hardly move. I got cortisone shots which helped, but I still had pain and could hardly walk. I felt 100 years old. I just completed a series of Euflexxa and I am walking normally again! I have over 40 stairs in my house and I am so far back to normal! This has been a lifesaver. I thought I was permanently disabled but I'm walking with no pain.
Have had knee pain for going on 10 years. Got to the point I couldn't take it any more and went to an ortho doc. He said right knee total bone on bone osteoarthritis and left knee is following but not completely bone on bone yet. He suggested Euflexxa shots, saying only other treatment would be a partial knee replacement. I figured it wouldn't hurt. I had the shots in December, 2012. First shot, no difference. Second shot, seemed to feel better, 3rd shot no change. About a month after getting them my knees still hurt. Figured it didn't work. But now two months later, I can actually go up and down stairs with minimal pain. I can go shopping and as long as it isn't all day affair, I do fine. Didn't take pain away completely, but is better
I took cortisone injections in my knee for 2 years the last few injections the pain was getting worse. Was tired of taking pain pills I found Euflexxa with my search. Very glad I did I took the print out to my ortho Dr. and ask him about what I found. I'm afraid of needles so they used numbing solution. I definitely did NOT feel any pain. Friday was my 2nd injection.
I am 45 with bone on bone osteoarthritis. MD said I'm too young for TKR. I had meniscal tear removed in July but still had extreme pain. After PT, MD recommended Euflexxa. Figured I'd give it a try-can't hurt. I finished my 3rd injection 4 weeks ago. Climbing stairs and walking is easier and less pain. There are days that the knee pain is worse but that is handled by a dose of ibuprofen. I am no longer taking the max. of anti-inflammatories on a daily basis. These shots have made daily activities less painful. Allow 6 weeks from first shot to feel benefits and communicate with your MD of any issues. So far I'm hopeful.
Review by experienced8585 (taken for 2 to 5 years):
I just finished my 3rd series of 3 shots each. Give it 2-3 to weeks after your last shot. Stay away from cardio and ice it daily. This is truly an amazing product. It hurts during and after and take it easy.
I went in today for my first of the 3 injections of Euflexxa.. I had psyched myself out pretty bad by reading some of the reviews so I wanted to at least share mine because it was a good experience. I am no fan of needles or injections and had great difficulty after going through Prolough therapy injections. But this was 2 seconds of pinch, a little burn discomfort but nothing compared to what I was worried it would be, and my knees feel better now than when I went in today. So for now, I have to say I am glad I did it and will be continuing with the other 2 injections in the coming weeks. Best of luck to everyone and pain free days!
Had first series a year ago, no pain or swelling after injections. My knees are bone on bone and doctor wanted to do knee replacement, too much arthritis and due to age they did not want to do arthoscopic surgery. I refuse steroid injections as they only mask the problelm. I am very sensitive to medications so I was very worried about a reaction from Euflexxa but had none. Pain was gone after 2nd shot and has lasted a year. Just had next series in left knee and am having right knee done starting next week. The only other option is knee replacement and after what happened to my husband, will only do it if the pain becomes unbearable. Totally satisfied with euflexxa
16 users found this comment helpful.
After highly successful results (2 years relief per series) my insurance insisted on Euflexxa). Following completion of series of three shots, my previously comfortable knees are completely destroyed. My range of motion is very limited and walking long distances is painful.
Review by Anonymous (taken for 6 months to 1 year):
Had first series 6 months ago and had to wait the full six weeks for relief. I would say that the pain subsided at that point but not completely. I have just completed my second series six months later and the relief was immediate and complete. I am pain free! Had some headaches at the back of my head but nothing bad enough that I would not continue with this life changing experience.
One day after the first injection I could tell a difference - no start up pain. The injections were painless. The doc put a cold numbing substance on the skin and when he injected it I couldn't even feel it. I had my last injection this morning, equally painless (the PA did it this time). I still have a lot of stiffness and am hoping now that I have all 3 to see some relief in the next few weeks.
This is my 2nd series and the 1st lasted almost exactly 6 months until the pain
cam back in my left knee. Today I had my 3rd shot in this series and the injection itself caused me considerable pain. Several hours later it still doesn't feel great.
I'm going tomorrow for my third Euflexxa shot. I was told I am not bone to bone but getting there. Severe arthritis in left knee. PKR is about 3-5 years out so Dr's say (3 opinions) For awhile the the NSAID's worked, corticosteroid shots lasted about a month. Knee pain comes and goes and flares up and worse each time. I am real encouraged that some have gotten years out of it. I am only 57 and like to work out everyday, but my knee has held me back. The Doctor's have told me my knee is strong, I can't hurt it by working out I just need to manage the pain, and keep tabs on the swelling with ice. I felt 75% better after first shot, the second hurt for a few days. Now it feels great. I hope this keeps getting better.
15 users found this comment helpful.
My doctor recommended Euflexxa in a severely arthritic left knee after 18 months of cortisone shots. The cortisone worked very well but there were concerns about using it "long term". I had the 3 rounds of shots, with the last round 5 weeks ago. I have more pain now than before the shots. I am woken more at night with pain, and have more constant pain throughout the day. The only benefit from the Euflexxa is a mild increased tolerance for kneeling.
10 users found this comment helpful.
I am in the middle of my second course of Euflexxa. I had it six months ago, and the pain relief was significant.
One thing to note is that your doctor should place the injection exactly where your arthritis is. No improvement could mean he or she is not doing the injection in the right place.
Another thing to note is that your activity tolerance in the first 48 hours after a Euflexxa shot can vary tremendously. I think most doctors use local anesthetic, and last shot I "felt fine" and was walking around and using short flights of stairs too much, resulting in severe pain that night (Percocet needed) and still a lot of pain the next day. The third day I was fine though.
Today I got a shot and I am taking it easy to avoid pain.
14 users found this comment helpful.
I recieved my second injection of Euflexxa today. After the first one no relief the doctor said alot of people don't feel relief after the first one but after the second maybe. He said that a month after the third injection if no relief then it did not take. The medication has a 50-50 chance. If this doesn't take then I am looking at a knee replacement. So we will see.
12 users found this comment helpful.
I received my 1st Euflexxa injection today in my right knee. I'm only 30 but have had knee problems since I was 9. I'm now bone on bone in that knee, and my left isn't far behind. I can't have my Fulkerson until the last shot 6 weeks, so it's either do the shots or live with my pain. I must say, this 1st shot has left me in a world of hurt. The shot itself was pain-free (having used ethyl chloride numbing spray) and I walked out perfectly fine. Here it is, 8 hours later and my knee hurts worse than it has in a while. I hope after I hit that 2 day mark it will get better. Only time will tell though. I just wish they'd tell you the '48 hour pain' could be this severe.
24 users found this comment helpful.
I just had the 3rd injection in both knees. Noticed a slight decrease in pain after the first one and no real difference after the second. I have bone rubbing on bone on the inside of my knees. Walking more than 50 yards without resting my knees is agony but I can bike ride without much pain at all so I take a spinning class twice a week for exercise. I would like to be able to walk again without severe pain my dog is getting fat as am I. I really pray for a decrease in pain in the next 6 weeks.
10 users found this comment helpful.
I have had for forty years and have primarily used exercise to combat damage to knee. It has gotten worse over that past year as I approach 60. I was offered different treatments because this one had least amount of side effects. I was very impressed the relief to pain and the general feeling in the joint. I am sold and plan to monitor how long the relief lasts. For now I would recommend it to my friends.
16 users found this comment helpful.
Immediate difference after the first shot - what a relief! Subtle differences after shots 2 and 3. Got my 6 month booster and was relatively pain free for 1 full year. Doctor said I was a good candidate for Euflexxa because the arthritic damage was not too severe yet. Time to get another booster.
15 users found this comment helpful.
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