Skip to main content

Xifaxan User Reviews & Ratings (Page 2)

Xifaxan has an average rating of 6.4 out of 10 from a total of 89 reviews on Drugs.com. 59% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Xifaxan

  • Bon...
  • December 8, 2016

For Hepatic Encephalopathy "Miracle drug is the first comment that comes to mind . I have end stage liver disease and currently wait patiently on the transplant list . I cannot explain my life or more even my unbearable existence I have undergone in the last several years . I began having difficulty with concentrating and unable to focus . I was so frustrated with myself living a life of total confusion to a point that I was in constant fear . My long term physician prescribed the medication to decrease the ammonia elevated by my failing liver . I was at a point that I was so depressed and had no desire to wake up in the mornings . I began taking the medication in disbelief and only as a last resort . I need more room to elaborate my response"

10 / 10
Was this helpful?YesNo
46 Report
  • Kahuna
  • August 3, 2017

For Hepatic Encephalopathy "$1375 with ins and ins won't cover but $12.50. Highway robbery and not worth it in my opinion. Will try and fix some other way. Drug companies should be ashamed and BC/BS should be abolished. You all high and mighty CEOs need to think about the patients,"

Was this helpful?YesNo
42 Report
  • Peewee
  • Taken for 1 to 6 months
  • September 18, 2019

For Hepatic Encephalopathy "Hi I have end stage liver and could not use bathroom for a bowel motion unless I took a bunch of lactulose to go, and when I did it was crazy I pooped my brains out. But I was having a problem because it would make me a prisoner in my home. Then I tried Xifaxan and after taking for three days no result, fourth day bingo and I stayed using it and it was more tolerable than lactose. So I feel much better. So I go to my gastroenterologist and told him it worked great but I now have heart failure "" not good"" "

10 / 10
Was this helpful?YesNo
31 Report
  • Anonymous
  • Taken for less than 1 month
  • June 12, 2014

For Irritable Bowel Syndrome with Diarrhea "This was given to me for SIBO (I've suffered from irritable bowel syndrome for years). I took it 3x/day for 14 days. Although I had no side effects from this medicine it did not help with resolving my SIBO. I even did another test for SIBO after I took the antibiotics and there was absolutely no change. Also luckily my insurance covered so it was $70 but without insurance its around $900!"

3 / 10
Was this helpful?YesNo
54 Report
  • Tired...
  • Taken for 1 to 6 months
  • April 6, 2016

For Irritable Bowel Syndrome with Diarrhea "I've had IBS-D for 25 years. Was always told there was nothing the medical community could do about it. So I suffered through it and took lots of immodium. So when I saw advertisements for Xifaxan I was so hopeful. Saw a new GI Doc and he immediately told me that this med was the best hope for IBS and that it's effectiveness was terrific. So I was so very, very hopeful this would work, and it did,,,,for the 14 days I was on it. The day after stopping my 14 day regime my extreme bloating was back and within a week my symptons were exactly as before. Now after 6 weeks my symptoms seem even worse. Going back to the Doc in 6 weeks. Will see what else might help. Good luck to all of you! It's a terrible disease to have to deal with!"

3 / 10
Was this helpful?YesNo
46 Report

Are you taking this medicine?

  • SickT...
  • Taken for less than 1 month
  • April 22, 2016

For Irritable Bowel Syndrome with Diarrhea "It started to work during the two weeks I was one it. I was still going to the bathroom but it wasn't that awful urgent you better go now or have an accident. That two weeks was much better. However, once it was over I have been worse than I was even before the medicine. Now I have severe stomach pain, foul smelling gas and stool, I'm very bloated and when I get the feeling I need a bathroom I need to find one fact because it WILL come out no matter if I'm in the bathroom or not. I really had very high hopes that this would be just what I needed to help. I've had IBS-D all my life but it was diagnosed years ago when I was 16."

2 / 10
Was this helpful?YesNo
43 Report
  • Krobar
  • July 5, 2013

For Crohn's Disease "Xifaxin was the only medicine that was able to get me off steroids and into remission with my Crohn's disease. I had been on steroids for 2 years and had 2 surgeries for blockages. I took a two week course of this and within 3 days I was having normal bowel movements. Pain free after a week. Six months later I had another attack, took Xifaxin again with same results. In remission now for 3 years."

10 / 10
Was this helpful?YesNo
53 Report
  • biker...
  • June 2, 2015

For Irritable Bowel Syndrome with Diarrhea "Tested positive for SIBO. I had asked my GI doc for that test. Was happy to have an answer after years of suffering. I am also hypoglycemic, so the actual TEST for SIBO had my blood sugar super low...probably 2 days to recover from that! The first 2 days on the drug I have felt dizzy and tired and my arms super tingly (?). But the BM's improved immediately so I didn't want to stop the Xifaxan. Now at 4 days, I'm not sure. Sometimes I start feeling amazing.I am also following a diet for candida and paying close attention to food combining. Just today started feeling the abdominal cramping come back! Really not sure what to do here...."

7 / 10
Was this helpful?YesNo
45 Report
  • Jackie...
  • Taken for less than 1 month
  • June 22, 2019

For Hepatic Encephalopathy "My HE (hepatic encephalopathy) did 180 degree change on Xifaxan. Better mentally, peaceful, actually. My wife and my friends noticed the improvement in me after 2 weeks on 550mg, twice a day. Still take lactulose because cirrhosis is stage 4."

8 / 10
Was this helpful?YesNo
28 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 9, 2019

For Irritable Bowel Syndrome with Diarrhea "I’m on round two of taking Xifaxan a two week, 550mg 3x daily regimen it is for SIBO (small intestinal bacterial overgrowth). My insurance, thankfully, paid for it both times. The first round, I was symptom free for the entire two weeks. Two days after finishing, my stomach pain and excessive gas returned. So I asked for another round. I’m one week into the second round and it is a godsend for my stomach symptoms. However, I think it has messed with my menstrual cycle as I am bleeding in between periods since I started taking this. It has also caused a yeast infection BOTH rounds. Other than that, it was extremely effective for the stomach issues. I just hope it killed the SIBO off! I don’t think my insurance will cover it a third time! It was $2400.99!"

10 / 10
Was this helpful?YesNo
27 Report
  • Harley
  • February 8, 2016

For Irritable Bowel Syndrome with Diarrhea "I do not recommend this drug at all! I have had IBS for 6 years this drug made my diarrhea worse!! I had great hopes that this drug was going to give me some relief, not so. I do believe that an antibiotic will one day cure this problem, I was given a common antibiotic for a sinus infection on two different occasions which not only cured my sinuses but also stopped the diarrhea for months. This drug is not the cure, not to mention the fact that is drug cost nearly $2000.00 please do not assume that I am complaining due to cost, this drug cost me 25.00, my insurance company was the one who paid. I would suggest to this drug company, Go back to the drawing board!"

1 / 10
Was this helpful?YesNo
40 Report
  • Dorch...
  • Taken for 5 to 10 years
  • August 12, 2016

For Irritable Bowel Syndrome with Diarrhea "I have had IBS-D for the past 8 years and am able to manage it with a regular regime of Xifaxan for the past several years. Every 6 weeks, I go on a 10 day regimen of Xifaxan and, yes, it does get worse when I'm not on it. But I can control the diarrhea, and somewhat the bloating. The bloating gets worse with my diet. So watching gas producing foods is a must."

10 / 10
Was this helpful?YesNo
37 Report
  • Anonymous
  • May 30, 2008

For Diarrhea "I wish Xifaxan wasn't so expensive, because it has changed my life. I noticed a huge change in the range of foods that I could eat, and the level of chronic pain and diarrhea I was having, after taking a full course (which left me broke)."

9 / 10
Was this helpful?YesNo
61 Report
  • Anonymous
  • November 22, 2011

For Traveler's Diarrhea "Returned from a trip to Kenya, Africa and brought back an unexpected guest which caused my diarrhea for two weeks. Tried the usual antibiotic regimen along with Questran, neither of which worked with total success. Tried Xifaxan in combination with Probiotics and the cure was virtually overnight. I will definitely remember this and refer to anyone I know with similar problem."

9 / 10
Was this helpful?YesNo
48 Report
  • Anonymous
  • September 23, 2009

For Crohn's Disease "It took few days for it to start working. I'm taking 2 pills a day. First few days felt bad cramps but after that it felt like a complete cure. No bathroom trips, gained weight, I can eat anything without feeling bloated."

10 / 10
Was this helpful?YesNo
52 Report
  • Lulu
  • August 25, 2018

For Irritable Bowel Syndrome with Diarrhea "I took this drug for my IBS-C .. while I was on it, it did help with my pains but not my bloating after I ate. It actually made me more constipated than before. Just a week after my last pill I can’t eat anything without having pain and a swollen stomach included gluten free. Just a way for the doctors to get a kickback or a percentage!! Sad world that we are living in.."

3 / 10
Was this helpful?YesNo
25 Report
  • SHano
  • August 5, 2020

For Irritable Bowel Syndrome with Diarrhea "Worked great! Took a couple of treatments. I have not had a problem with IBS since. No side effects. The reviews about SIBO should be removed from the IBS reviews. This drug is indicated for IBS-D not for SIBO."

10 / 10
Was this helpful?YesNo
18 Report
  • Been...
  • December 13, 2019

For Irritable Bowel Syndrome with Diarrhea "I paid $750 for 42 pills. The coupons only work if you have no insurance and are dead broke. I took the 550 mg three times a day for 3 weeks. I had only minor improve. This drug company should be ashamed. Totally outrageous."

2 / 10
Was this helpful?YesNo
20 Report
  • Ymel
  • Taken for less than 1 month
  • October 7, 2020

For Irritable Bowel Syndrome with Diarrhea "I started taking Xifaxan for suspected IBS, and started having severe abdominal cramping within a few days. I called my doc 6 days in and told him I was in severe pain, and had a low grade fever, and he told me it’s normal, to finish the 14 day course of treatment. I have suffered SEVERE lower abdominal cramping. This is so bad I can’t stay silent when it happens, moaning and crying like a drama queen!"

1 / 10
Was this helpful?YesNo
17 Report
  • Notha...
  • Taken for less than 1 month
  • October 16, 2019

For Irritable Bowel Syndrome with Diarrhea "I had IBS and Explosive Bowel movement’s at any time. Spent $422.00 for this medicine in the hopes it would solve my problems. It did not. Took the recommended dosage till the prescription was complete."

1 / 10
Was this helpful?YesNo
20 Report
  • Jack
  • Taken for less than 1 month
  • September 5, 2020

For Irritable Bowel Syndrome with Diarrhea "I had to stop this Xifaxan after 9 days because it was making my IBS-D even worse. Two days later and I'm still terrible. This drug is not worth the gamble when the best you can hope for is "up to 6 months of relief.""

1 / 10
Was this helpful?YesNo
17 Report
  • SMiller
  • Taken for less than 1 month
  • August 19, 2016

For Irritable Bowel Syndrome with Diarrhea "Sadly this medication gave no relief at all and actually made things worse... Severe nausea and vomiting on top of constant diarrhea, not an easy thing to multi task if you know what I mean. But hey, all meds work differently for different people. Hope others had better luck than I did."

1 / 10
Was this helpful?YesNo
29 Report
  • RobinLP
  • Taken for less than 1 month
  • July 23, 2016

For Hepatic Encephalopathy "I am Stage 4 Cirrohsis, diagnosed with Hepatic Encephalopothy. Started Xifaxan about a week ago. I was concerned with a few comments from a different doc about this medication. I'm glad I found this site because I feel so much better reader about your experiances. I am so looking forward to feeling better!"

Was this helpful?YesNo
29 Report
  • Theba...
  • Taken for less than 1 month
  • October 24, 2020

For Irritable Bowel Syndrome with Diarrhea "I’ve had IBS-d for as long as I can remember. Finally cracked and went to a doctor. After 2 months of blood work, CT scans, and a colonoscopy they didn’t find anything wrong. I was depressed hearing ”we don’t know what’s wrong.” Doctor calls me one day and says he wants me to dry a drug- I’d do anything at this point for relief. In comes xifaxan. I had really bad nausea the first day for about an hour then nothing after that. After day three I didn’t have any pain, bloating, or mad dashes to a restroom to unload. I was having normal one a day bowel movements with “ghost” wipes. Lasted about a month and a half and the symptoms are starting to reappear. I have a prescription for 3 treatments so I’m going to go at it again and see what happens."

10 / 10
Was this helpful?YesNo
16 Report
  • IBS...
  • July 15, 2017

For Irritable Bowel Syndrome with Diarrhea "Thanks to my doctor for prescribing Xifaxan. I've only been on it for about a week and my life has changed dramatically. It's so good not to have to head to the bathroom 3 or more times a day with diarrhea. The only side effect is some constipation but you go when you want and usually only once. No more What if scenarios. I also have a better appetite and am gaining some weight back. Thanks Doc and Xifaxan."

Was this helpful?YesNo
26 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.