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Progesterone User Reviews & Ratings (Page 3)

Brand names: Prometrium, Endometrin, Crinone, Cyclogest, First Progesterone MC5, First Progesterone MC10 Gestone Milprosa

Progesterone has an average rating of 6.5 out of 10 from a total of 74 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Progesterone

  • Cessi...
  • Taken for 1 to 6 months
  • January 8, 2020

For Premature Labor "I began having pre term labor contractions at 20 weeks. After being discharged from the hospital the contractions continued I researched and saw that progesterone had helped some women maintain pregnancies so I suggested this to my doctor and began taking once a day. (Annoyed that I had to suggest it instead of my doctor but that’s the medical establishment). I continued to have contractions for the next months and went to the hospital several more times but since I wasn’t dialating or losing blood or fluids I wasn’t in active labor. I did have my daughter at 32 weeks but I credit progesterone for helping us make it that far. Despite being premature she is healthy and catching up quick! I would strongly recommend for pre term labor contractions!"

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  • Yogi
  • Taken for less than 1 month
  • October 17, 2018

For Uterine Bleeding "I was prescribed progesterone by my GYN for unusual, post menopause spotting coupled with the thickening of my uterine lining. He said it might reduce the uterine lining. Mine is 16 mm and normal is about 4 mm. He did not say how this drug would achieve this. I do not know if the lining will evaporate or if I will have a period. I have been on it for 30 days and the spotting has stopped. I will now have a vaginal ultrasound to see how thick the lining is. I can't imagine it would be thinner because how would that happen if there was no period. I give the drug high points because I slept really well and there were no odd symptoms, no breast tenderness, no real dizziness. I took it at bedtime of course."

8 / 10
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  • night...
  • March 18, 2019

For Progesterone Insufficiency "Just four times a year? I'll take it. I need this Rx because I am on an estrogen patch for severe menopause symptoms. My dose is intra-vaginally, 200 mg, every other night for 12 nights, every 3 months - so 4 times per year. I never forget it because I begin my regimen at the start of each season. This method of progesterone by far right easiest method to tolerate for me. I won't use these hormones forever, but for right now, they help. The first few days, I get mild PMS symptoms - to be expected - then usually begin menstruating, which means it did its job. The PMS rises and falls with stress levels and other issues. I manage it by doubling my exercise routine, adding meditation; - high stress levels drive many PMS symptoms. I also switched to a Mediterranean diet a few years ago. I strongly recommend these things as they have a proven record of reducing PMS symptoms."

8 / 10
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Frequently asked questions

  • Amber
  • Taken for less than 1 month
  • September 30, 2012

For Progesterone Insufficiency "I am using this in my FET cycle for IVF. I am 4 weeks, 4 days pregnant. I was taking 2 vaginal inserts (100mg) each per day but after blood tests came back showing a very low Progesterone level, my Dr is having me take an additional 600 mg per day in pill form (200 mg, 3x per day). My Dr warned me that I would be very tired and possibly dizzy. I have been on the pills for 3 days now and have noticed that my breast are very tender and swollen which they weren't before and it does make me a little drowsy but not bad, It's manageable. I go back on Tuesday to check my levels."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 18, 2016

For Uterine Bleeding "I am 44 years old and taking AK2 generic for Prometrium for unusual uterine bleeding. The doctor put me on this to stop my irregular bleeding but so far after 4 days of taking I am still bleeding with some clots. I am supposed to take this for 12 days. He said my progesterone levels were really low and the endometrium had built up too much in my uterus. The first time I took it I got really dizzy and sleepy so now taking at night. I have had bad headache on two different occasions and fast heartbeat and definitely feel brain fog and can't think. This medicine is no fun. I had normal cycle up until a month and a half ago but a few months before that noticed reduced cycle so having low hormonal levels I guess."

3 / 10
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Are you taking this medicine?

  • crsmre
  • Taken for less than 1 month
  • March 13, 2023

For Endometriosis "Hi, I read all the reviews prior to taking this medication. I was quite concerned with the side effects a lot of people were experiencing. I decided to give myself a week of taking the meds and then I would re-evaluate my decision. I was placed on this medication to help with symptoms of Endometriosis, Adenomyosis, fibroid, and cysts, and to help reduce the inflammation in my uterus. I started taking (Errin .35) medication at dinner time. The first three days, I did experience some pretty heavy fatigue, and on days four and five I had some facial acne. I am now on day ten and don't have any side effects. I also weighed myself on day seven and had no weight change. My mood hasn't changed much from where I was before. I have not had a cycle yet as I am on week 2. All in all, I am doing well on this medication. I will try to update you if anything changes in the future."

7 / 10
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  • Shern...
  • Taken for 1 to 6 months
  • December 12, 2016

Prometrium (progesterone) for Premature Labor "Mild side affects such as fatigue and hunger, horrible headaches if not taken at all. Seems to work, however for the price paid for the medication seems like they could include a applicator like the ones they give with gels and OTC yeast meds etc. It's not fun or very easy trying to shove pills in your VAGAY with your fingers every single time you must use this medication."

6 / 10
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  • savet...
  • July 9, 2016

For Endometrial Hyperplasia, Prophylaxis "I take this med because I use vivelle estrogen patch and need progesterone every 3 months to prevent uterine lining buildup. I take 200 intravaginally, every other day for 12 days - 6 doses total - every 3 months. At first dose, I was slammed with drowsiness, lower back pain, hot flashes at night, restless sleep and weakness in legs. I had cramps, but did not get a period. By the last dose, the side effects were better. but still it was no picnic. It's a small price to pay however for being able to take vivelle dot and get estrogen, and as far as I understand, the easiest way to take progesterone as I don't want a uterine implant."

7 / 10
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  • Kano
  • March 18, 2020

For Gender Dysphoria "My gender clinic doctor recommended that I take a progesterone only based birth control pill to stop my period before and while I start testosterone. I’ve been on it for about a week and I’ve had spontaneous bleeding even though I started the pill at the very end of my cycle. I’m also getting really tired during the day and having a hard time staying asleep at night."

7 / 10
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  • Baby
  • Taken for less than 1 month
  • January 27, 2017

For Progesterone Insufficiency "I was prescribed progesterone in early pregnancy due to insufficiency. I switched pharmacies and this p-2 progesterone pill was a new brand that I was switched to. Two hours after taking the first pill (vaginally, as directed) I had spotting. This spotting continued for three days while I was on this pill. One day I didn't take it until the late afternoon and all morning had no bleeding. Then two hours after taking the pill I started bleeding again. I was far enough along in my pregnancy that when I brought this up to my doctor he said that I could safely stop taking it. Ever since I stopped taking this pill, the bleeding had since stopped too! I would not recommend this brand of progesterone."

1 / 10
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  • MDDMom
  • Taken for 1 to 6 months
  • December 13, 2021

For Perimenopausal Symptoms "Neurologist wanted me to consult with menopause expert to consider HRT. She declined, Estrogen hormone replacement therapy is contraindicated, as I have liver problems, migraines with aura (newer research busted that myth) and family history of stroke. 9 months ago, I started having hot flashes every day around 2pm for 3 hours. Intense long flashes, then chills, nausea, migraine attack. Brutal! Couldn’t work, couldn’t go out without a change of clothes and hair ties! New Gyn started me on low dose progesterone (Incassia). Unbelievable difference. Hot flashes are lesser, shorter, but vary in time"

8 / 10
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  • Mini
  • June 13, 2020

For Amenorrhea "I’ve been taking this progesterone pill for nine days orally. The first few days were fine, just had a bit of nausea. Then around my 5th night when I took it at night, about an hour and a half later I had dizziness and felt like I was in another world. It feels like laughing gas. I also am noticing bloating and on the next day headaches. It also makes me have mood swings once the dizziness has left my body. It makes me very tired, and I sleep great. I’ve had these symptoms since then. No sign of bleeding since then and I am not sure if it will work for me. But it says if you have these symptoms you will get results so I’m hopeful."

5 / 10
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  • Anonymous
  • June 8, 2011

For Premature Labor "After each injection I would be exhausted the next day. I would have severe depression which seemed to get worse with each injection. I'm only 25 weeks and have to continue taking it until I'm 34 weeks. Will see if it helps me go full term."

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  • Lois...
  • Taken for less than 1 month
  • November 10, 2020

For Perimenopausal Symptoms "This medicine smells strongly chemical and made me bleed for weeks. I had to switch to Dr. Reddit’s brand. Would not recommend. 200mg I had to pay $100 out of my own money because my insurance had already paid for this one. But I really didn't like it so much, I paid for the Dr. Reddy’s."

1 / 10
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  • Anonymous
  • May 17, 2011

For Premature Labor "I'm taking this medication to prevent premature delivery. With EVERY injection, I have gotten a debilitating migraine, not to mention soul-crushing depression. With no other options, I have to stay on the medication until I reach 32 weeks. "

3 / 10
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  • qaf
  • Taken for less than 1 month
  • June 12, 2022

For Female Infertility "Repeat miscarriages in first trimester. Given 200mg progesterone to take after ovulation until period to support pregnancy. Took it for one cycle and became suicidal, depressed, and no am not experiencing a period. I used to have irregular periods and then had regular periods for almost 3 years, during which I've had multiple losses. Now am back to being irregular after this progesterone treatment. I stopped taking it because of the suicidal ideations."

2 / 10
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  • Mary...
  • Taken for less than 1 month
  • May 1, 2024

For Uterine Bleeding "Progesterone 5mg 2x per day... After 0.35 mg for 90 days did not stop my menses, and may have even caused a 90-day bleed, I stopped it. However, I was then put on this 5 mg two times a day and within three or four days the bleeding stopped. It did its job! So for that, I give it a 10. Unfortunately, after a few days, I had body aches like I was getting the flu; I hurt from head to toe. It took me a few days to figure it out over the weekend while no doctor was in the office, but the cause of my body aches, fatigue, and actual jitteriness was this medication. Due to needing my menses completely stopped for proper OBGYN testing, I still have to take this medication, it makes me feel awful! So for the feeling of yuckiness, for lack of a better word, I give it a 2. Overall, a 6 since it did the job I needed."

6 / 10
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  • Anonymous
  • March 10, 2011

Prometrium (progesterone) for Uterine Bleeding "It saved my baby. I was was showing signs of miscarrying because of my hormone levels. I took this for 12 weeks. The bleeding stopped the next day and I now have a healthy little girl!"

10 / 10
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  • Anonymous
  • December 31, 2008

Prometrium (progesterone) for Progesterone Insufficiency "I experienced a few mild side effects - mainly mild nausea and irritability. Well worth the improvement in my overall health."

8 / 10
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  • jojo
  • Taken for 1 to 6 months
  • April 7, 2023

Prometrium (progesterone) "Two months into taking this med, I have found it's making me feel ill. Dizziness, shortness of breath, lethargy. I've had test after test. Then realized this all happened after starting this med."

1 / 10
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  • Fem54...
  • Taken for less than 1 month
  • October 2, 2020

Prometrium (progesterone) for Perimenopausal Symptoms "I developed severe tinnitus and after 1 week couldn't take generic progesterone for Prometrium any more."

1 / 10
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  • Nic
  • Taken for 1 to 6 months
  • November 8, 2018

Crinone (progesterone) for Progesterone Insufficiency "I used it for IVF/Frozen Embryo Transfer. I’m due with our baby any day now, it was super easy and convenient to use. I’d much rather do this than a intra-muscular shot into the butt every day."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 24, 2015

Crinone (progesterone) for Progesterone Insufficiency "After a few days of use I had such horrible itching it prevented me from sleeping. The itching took about a week after discontinued use to subside."

4 / 10
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  • Jules
  • Taken for 1 to 2 years
  • September 11, 2019

For Progesterone Insufficiency "I get freaky and can't remember what happened the next morning!"

10 / 10
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  • Frenchy
  • Taken for 1 to 6 months
  • March 20, 2018

Prometrium (progesterone) for Uterine Bleeding "Helps bleeding. Makes asthma worse. Helps me sleep."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.