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Progesterone Pregnancy and Breastfeeding Warnings

Progesterone is also known as: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Menopause Formula Progesterone, Prochieve, Progest, Prometrium

Progesterone Pregnancy Warnings

Progesterone has been not formally assigned to pregnancy category by the FDA. Progesterone vaginal inserts can be used as part of in vitro fertilization treatment for luteal phase support during the first months of pregnancy. Animal studies have revealed little to no evidence of impaired fertility or fetal harm. Studies in women have not demonstrated significant increases in fetal malformations. Progesterone is only recommended for use during pregnancy when benefit outweighs risk.

A single case of cleft palate was observed in the child of a woman using progesterone in early pregnancy, however, causality has not been established. Rare instances of fetal death have been reported in pregnant women receiving progesterone for unapproved indications.

Progesterone Breastfeeding Warnings

Detectable amounts of progesterone have been identified in the milk of nursing mothers, however, the effect on the nursing infant has not been determined. The manufacturer recommends that progesterone be administered to nursing mothers only when clearly necessary.

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