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Pregabalin for Neuropathic Pain User Reviews (Page 5)

Brand names: Lyrica, Lyrica CR

Pregabalin has an average rating of 5.7 out of 10 from a total of 327 reviews for the treatment of Neuropathic Pain. 44% of reviewers reported a positive experience, while 36% reported a negative experience.

Reviews for Pregabalin

  • Anonymous
  • Taken for less than 1 month
  • July 17, 2022

Lyrica (pregabalin) "Horrible experience, this drug Lyrica almost made me lose my mind. I was prescribed this back in the spring of 2021 for chronic pain in my neck and shoulders at a low dose. Was on it less than a week when the side effects kicked in- night terrors that made it impossible to sleep, severe anxiety including ++ panic attacks, severe restlessness, paranoia and abnormal + strange thought processes. I stopped the medication after speaking to my doctor around the 2 week mark but the side effects took another 2-3 weeks to fully disappear. At one point I remember sitting on the bed rocking back and forth humming to myself, unable to get a grip on anything that was happening. Thankfully I felt like myself again after a few weeks, but at the time I felt like the med had permanently changed my brain. From what I've heard this experience is VERY rare but I feel like it's important to get it out there as a warning nonetheless."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • November 2, 2022

Lyrica (pregabalin) "Worst drug I have ever taken. I spent many many months reviewing this drug and saw mixed reviews, but became more and more desperate to find something to help my nerve pain from chemo and bulging discs in my neck. Worst decision ever! I have had many different drugs that have caused side effects due to having to have chemo etc . This is by far the worst. I realise everyone is different and react differently to drugs but Lyrica is so terrible DON'T TAKE IT ! So many side effects and even though I was only on it for 5 weeks the withdrawal symptoms were shocking and no pain relief at all ."

1 / 10
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  • Alydara
  • Taken for 6 months to 1 year
  • July 26, 2019

Lyrica (pregabalin) "I’ve been on Lyrica for about a year now. Have gradually increased dose to 200mg 3 x day. Benefits: Reduced painful “zingers” which I’d get down my fingers; Calmed the waves of pain up and down my legs and feet, especially at night; Reduced the pain in my toes and fingers; Issues: Legs, arms hand and feet feel like they’re badly sunburned all the time. Constipation, gas, distention. Disassociation. Insomnia and trouble with concentration."

3 / 10
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Frequently asked questions

  • CMR
  • January 26, 2016

Lyrica (pregabalin) "Like many others, my pain doctor had me on gabapentin first, then after several months without relief, switched me to Lyrica. Without a generic version available, it can cost a small fortune depending on your insurance. Without any insurance, 100mg capsules 3X daily, 90 pills will cost upward of $600! With my Part D, and not qualifying for "Extra Help" through the state, I'm now paying $140 for a 2 week supply, $280 monthly. That's a car payment! I have no idea what to do once the free samples run out, it's a very good medication but unaffordable. If your doctor tells you gabapentin (Neurontin) works the same, chemically there's no difference, that just isn't true. It may be similar, but Lyrica works much better with significantly less mg's"

8 / 10
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  • Rusty...
  • Taken for less than 1 month
  • July 12, 2019

Lyrica (pregabalin) "I had needles and pins from back, stenosis, disc bulging so was given Lyrica. Only took it 2 1/2 days as it made me feel terrible. Felt like a zombie, couldn't think straight, slurred words, tripped easily. My husband said I wasn't acting right, got irritated and angry very easily which I don't usually do. This was on 50mg and then I was going to 75mg. I stopped today and won't take it again. Not worth it to me."

1 / 10
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Are you taking this medicine?

  • Connie...
  • March 14, 2016

Lyrica (pregabalin) "I had cervical fusion at c4-5, 5-6, 6-7, after my surgery coming out of the operating room no one could touch my skin. I had loss sense of feeling on right arm left hand right shoulder was on fire pins and needles severe also on the back right side of tongue and throat. In the hospital they started giving me Lyrical 75mg 3 times per day that just took the edge off. Then I went to the pain Dr it was increased to 150mg 3 times a day and I had such relief to the point I could touch my skin, it has worked so great that when it is time for my next dose I begin to feel the pins and needles severe and the fire on my shoulders and hands. Amazingly it takes away that feeling as long as I take it every 6 hers. The problem I have had is weight gain"

9 / 10
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  • Nutty...
  • Taken for 2 to 5 years
  • December 7, 2015

Lyrica (pregabalin) "I have taken Lyrica for several years now and it has helped me so much with nerve pain. I use to take 200mgs twice a day for spinal and cervical stenosis, scoliosis(spinal fusion ) and cervical and lumber Spondylosis . I put on over 10 lbs in weight when I first started taking it, but with correct food choices , I lost what I had put on and more. I did at first have an increased balance problem. I now take 200mgs of Lyrica 3 times a day because I have been diagnosed with type 2 diabetes, I take metformin 500mg twice a day and I've got neuropathy pain. I have no side effects with Lyrica now.The other pain meds I am on is a 500mg Fentanyl patch and Arcoxia and Quinine for leg cramps. I live in the UK and get my pain medication free ."

10 / 10
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More FAQ

  • Anonymous
  • Taken for 1 to 2 years
  • September 26, 2017

Lyrica (pregabalin) "I was prescribed Lyrica for post shoulder surgery with continuing nerve pain radiating down the arm. Lyrica caused me to gain 20lb, slurred speech, blurred vision. I had edema in my ankles too. Since I would only take it two times a day, I would have rebound nerve pain that encourage me to take more Lyrica. After my Dr advised me about the weight gain, I decided to take myself off of it. It took 10 days to withdrawal from the drug but I'm glad I did. I'm a clinical Pharmacist and advised all on Lyrica to be AWARE of all the adverse effects of this drug."

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  • cherdoo
  • Taken for 1 to 6 months
  • March 17, 2015

Lyrica (pregabalin) "I've been on 75mg, 2x/day for 2 months. Difference is night and day! I have RA, nerve damage form a pretty bad accident, herniated discs and vein's are dying. I'm a mess. Tried everything, but Lyrica has been the one that worked. Not completely, but they may bump up the dosage, I'm told. Trying for 2 more months til I see my GP again. Lucky my insurance pays- otherwise I'd never be able to afford it."

10 / 10
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  • Anonymous
  • May 11, 2016

Lyrica (pregabalin) "I've had problems with my feet burning for several years. Every year it was worse than the year before. It got to the point that I couldn't stand anything on my feet. Lyrica helped a lot, with much less frequency and severity of burning. Finally some relief. Unfortunately, I had to discontinue because of side effects. I had almost all side effects listed in the info sheet. Most I could have tolerated, but the ones I couldn't was weight gain, confusion, and fast progressing blurred vision. Also, I had severe clinical depression over 18 years ago until I received the correct antidepressant. I've had no depression since. However, the Lyrica caused it to return, although not as severe. It also caused anger flareups, very unlike me."

7 / 10
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  • Weeper
  • Taken for 6 months to 1 year
  • April 2, 2017

Lyrica (pregabalin) "I started taken lyrica for trigger spots (burning painful hot spots through out my back) plus lower back pain. I began taking 150mg 2x a day. It was wonderful, no more daily nagging pain. However, the side affects started to out weigh the pain relief. I had to start taking a water pills because of the water retention, my memory& cognitive thinking were really effected. On three separate occasions, I was sent home from work because I was so drowsy I kept falling asleep. I was staggering, slurring my speech. My supervisor thought I had been drinking. It was very embarassing. If I did not have all these side effects, I would've stayed on these meds but it was getting out of control-my weight has sky rocketed also. I'm weening off.Pain is back."

2 / 10
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  • Zopdeep
  • Taken for 2 to 5 years
  • August 21, 2017

Lyrica (pregabalin) "My whole body would be on fire without Lyrica. My sensory neuropathy is so bad I wouldn't be able to eat most foods without terrible reflux pain that would burn my throat and face. It does cause fatigue (build up slowly) but it's a trade off for quality of life. I have none without it. Lyrica has been the only drug that works for my small fiber neuropathy that didn't suddenly stopped working for me. I've had to increase dosage over the years. I currently take 350mg day, targeting 400mg."

9 / 10
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  • Opraman
  • Taken for less than 1 month
  • June 14, 2022

Lyrica (pregabalin) "I began my Lyrica experience 8 days ago, and dear God, I hope it never ends. I am a Polytrauma motorcycle accident patient, and am 3 years post-accident. I had truly given up on being anything other than a "5/10" pain patient. My other meds include hormonal replacements for testosterone and Thyroxene, Cymbalta (60mg), Methocarbomal and Norco as needed for severe bouts, THC, CBD, CBN. I also occasionally use Flexeril if needed on bad muscle days, Ibuprofen, Amlodipine to control BP, topical ibuprofen as needed, hell, even horse-liniment and whiskey if nothing else is hitting the spot...I had over 20 spinal fractures from the accident, but miraculously nothing had displaced. Neck broken in 7 places, multiple thoracic and lumbar compression fractures, broken Sacrum and hip. I also had 2 pre-frontal brain-bleeds and creamed my pituitary (hence the BP meds and hormones). After 2 days on Lyrica, the pain simply switched off. I am stunned."

10 / 10
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  • Downt...
  • Taken for 6 months to 1 year
  • December 13, 2018

Lyrica (pregabalin) "Lyrica has made my pain worse in a way because I'm being forced to take it because it actually works, but it is not worth the side effects. The choice has become live in chronic pain or lose your sanity. I'll take the pain until I find something that works for me. Simple poison ."

1 / 10
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  • Older...
  • Taken for 1 to 6 months
  • March 6, 2017

Lyrica (pregabalin) "On narcotics, muscle relaxers for neuropathic pain from inoperable herniated discs, arthritis in back. Narcotics cut in half by doctor and prescribed Lyrica, 75mg once at night, then 75mg am and pm and on til taking 150mg am, pm. Nothing. Today an additional 75 mg to be added midday. Decided to check here before taking more. Wow. I have had left hand/arm jerks where my arm just flies up, once throwing iPad mini across the room, another time scatting nuts everywhere while chopping them. I now realize this condition started with Lyric and gets worse with increased dosage. I am going to slowly stop this drug because a) it does nothing for pain, and b) what has it done to my brain?"

3 / 10
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  • LMondry
  • September 1, 2015

Lyrica (pregabalin) "I was prescribe Lyrica for a pinched nerve in my elbow after a dislocation. The pain made physical therapy intolerable. With just one dose of 75mg of Lyrica, I could bend my elbow without wincing. Absolutely marvelous. Unfortunately there were 2 side effects that make me stop taking it. First one was that I fell asleep almost immediately after taking it for about 2 hours and my brain felt very foggy after I woke up. Second issue was a slight tightness in the chest and feeling a little out of breath. Not severe, but enough to let me know that I couldn't take it again. Made me sad because it really worked."

4 / 10
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  • Poszike
  • June 9, 2017

Lyrica (pregabalin) "My mum has been taking Lyrica for around three years. It has been a huge problem! Drugs.com has a page on Lyrica's Side Effects yet it doesn't mention is that it can cause a stroke. My mum has had three mini strokes. It has given her dementia, incontinence, she can't walk properly etc. She has many of the side effects mentioned. The doctor is slowly taking her off Lyrica and she almost back to herself."

5 / 10
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  • Floppy
  • Taken for less than 1 month
  • February 21, 2019

Lyrica (pregabalin) "I had hip replacement a month ago, and was told that I had ‘fallen foot’ after by the surgeon. He did say I was only the third person to whom this had happened. Nowhere in literature given was this condition even mentioned so off I went on internet to find out. On returning home, with splint in my shoe, I experienced classic feeling in feet like 100 bees or stinging nettles keeping me awake. Hip was great by the way. My G P called at my request and prescribed Lyrica tiny dose, I'm 77, a week later I am on two 25mg mornings, two 25 mg evenings and it s become manageable, not so intense. So yes, it s helped me."

6 / 10
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  • Rowena
  • Taken for 1 to 2 years
  • February 27, 2024

"Pregabalin has been fantastic for my pain issues. I am living with several chronic pain conditions: interstitial cystitis, instability of the ankle joints causing frequent sprains and surgery, two bulging discs in my spine, and a peripheral nerve injury (neuroma) with chronic regional pain syndrome. With pregabalin, I am able to manage a lot better than without it. I do get some side effects like some cognitive issues, but it’s definitely worth it. Sometimes I have taken 100 or 150 mg three times a day. I have also tried twice a day, but I get a lot more breakthrough pain doing that so I recommend three times a day as better, in my experience. I find it less helpful for my bladder and orthopedic pains, and most helpful for the neurological pain in my hand and also my back pain. It’s very important to take it on schedule because there are bad withdrawal symptoms, so I also recommend you reduce it very slowly, unless it’s an emergency. Also, I think it’s better than gabapentin!"

10 / 10
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  • Susan...
  • Taken for 1 to 2 years
  • August 14, 2015

Lyrica (pregabalin) "I've been taking lyrica for almost 2 years, I was prescribed gabapentin to begin with, and they kept increasing the dosage, until I was almost on the max dose of 3200mg, and my pain management dr prescribed me lyrica 100mg x 3 daily and it works for the most part. I don't have the side effects from it that most have, and it works to control the pain, although I do have neuropathy flare ups from time to time. I'm taking it as a result of neuropathy from spinal chord injury. and my insurance pays for it so no out of pocket costs. I recommend this to people who have nerve pain."

9 / 10
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  • Jessika
  • Taken for 1 to 6 months
  • July 22, 2017

Lyrica (pregabalin) "I was given lyrica 3 years ago for back pain from herniated disk. The pain down my legs at night was horrific. The pain in my legs went but I put on 12kg. I did not eat more in fact I ate less because of my weight gain. The Dr refused to believe that lyrica was the cause of the gain. Now 2 years later I have been given lyrica again because no other drugs worked. When will dr listen and learn about side affects."

3 / 10
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  • DMAD
  • September 10, 2017

Lyrica (pregabalin) "This drug in combination with another pharmaceutical products took the pain away which I was getting from an L3/4 - L4/5 disc protrusion. The pain was horrific which made me collapse twice and taken to hospital via ambulance. However I am now dealing with the side effects of the drug, which going by the list I have probably 25-30% of these. I have in the last few days finally got to not taking this drug at all and am coping on over the counter pain relief. But I am still experiencing major dizziness, coordination and confusion. This is majorly impacting my day to day life and stopping me from walking my dogs just a very short distance and even holding a conversation. Not happy with the side effect."

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  • Quique...
  • Taken for 2 to 5 years
  • February 21, 2015

Lyrica (pregabalin) "Due to a toxic neuropathy which causes an excess of electrical conduction through my peripherical nervous system and results in neuralgic pain specially in my legs, arms, hands, feet, torso & face I have been taken 450mg a Day. It worked for a couple of years but now my body tolerance has reduced its pain killing efect. Don't want to increase dosage and my neurologist seems at a loss as what to prescribe."

6 / 10
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  • Heldie
  • Taken for less than 1 month
  • June 26, 2017

Lyrica (pregabalin) "I have sciatica and I've been taking this medication (150 mg per day) for several weeks and have very few side effects except for blurred vision (close up, though my long distance vision is fine). Which is a challenge as my job requires quite a bit of computer work. I am wondering if this will last as long as I am on this medication."

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  • David...
  • August 31, 2013

Lyrica (pregabalin) "I simply could not go on without Lyrica. I have a peripheral neuropathy known as Charcot-Marie-Tooth disease. I experience numbness, pinching, burning, tightness, and severe pain in my feet and lower extremities. I have had to stop driving. The condition has caused a wasting of the muscles in my legs, which has led to problems with walking and balance. It is a progressive condition which I'm led to believe will one day cause similar symptoms in my hands and arms. As soon as I assume a horizontal position (as in going to bed), all the above symptoms return and I find that the Lyrica cannot control these very well. I take the maximum dose of 600 mg spread out over 24 hrs."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.