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Osphena User Reviews & Ratings (Page 2)

Osphena has an average rating of 4.9 out of 10 from a total of 45 reviews on Drugs.com. 28% of reviewers reported a positive experience, while 44% reported a negative experience.

Reviews for Osphena

  • wellk...
  • Taken for 1 to 6 months
  • February 19, 2020

For Dyspareunia "This product did absolutely nothing for me! I went through five months of pills just waiting for something to happen. But, all I did was fill my body with some type of synthetic drug that had zero impact on my problem. I would never recommend this product."

1 / 10
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12 Report
  • GaNat...
  • Taken for 1 to 6 months
  • April 6, 2020

For Dyspareunia "I've been taking Osphena for 3 months for painful intercourse. My doctor said give it 3 months and I did, but sex still hurts, and the side effects are pretty bothersome. Hot flashes, weight gain, bloating, and the worst is the bitchiness. My husband said he'd rather have his sweet wife back. I'm calling the doctor today, but leaning toward stopping it."

2 / 10
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9 Report
  • Peg
  • Taken for less than 1 month
  • February 28, 2018

For Dyspareunia "I am 30 years old, this med has been a blessing to my life!!!! After 4 days of taking it I could feel the difference. I recommend this med to anyone who may be experiencing this issue. I also haven't had any side affects."

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12 Report

Frequently asked questions

  • Sunsh...
  • Taken for 1 to 6 months
  • September 13, 2020

For Vaginal Dryness "I’ve been taking Osphena for 1 month now. The first week started the hot flashes and night sweats during the night that wakes me. Muscle spasms in my legs. Weight gain and feeling bloated. My Dr advise to continue for a least 12 weeks, not sure if I can manage 2 more months of side effects."

4 / 10
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7 Report
  • Anonymous
  • June 14, 2020

For Postmenopausal Symptoms "I took this medication for 3 months. The side effects are just not worth it. I experienced horrible hot flashes and sweating profusely. You will also gain weight on this medication. My doctor assured me that neither were a side effect... not true. Just read these reviews."

1 / 10
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7 Report

Are you taking this medicine?

  • Ann
  • Taken for 1 to 6 months
  • November 6, 2019

For Atrophic Vaginitis "When I started the Osphena I felt better, the hot flashes were horrible. Didn't notice any difference in sex, still hurt. By 3rd month slight headache constantly and leg cramps were bad. Called doctor and stopped taking."

4 / 10
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7 Report
  • Mew
  • Taken for less than 1 month
  • August 25, 2020

For Vaginal Dryness "Ok so I started over a week ago on Osphena and everyday I have horrible migraine. I'm tired and am starting to feel the weight gain bloating also. No night sweats, or leg cramps. But I am not going to continue. I read the side effects and it's not worth it to me."

2 / 10
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5 Report
  • Dmp
  • Taken for 1 to 6 months
  • October 19, 2020

For Atrophic Vaginitis "Have been using Osphena for approximately 4 months. It has helped with the dryness but now the bloating is unbearable. All of a sudden my stomach has gotten like a beach ball and feels horrible. I’m sure this is what it is from. Asked to go back on estate cream."

2 / 10
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3 Report
  • Nikki
  • April 5, 2020

For Vaginal Dryness "My Dr had me try Osphena. I have been taking it for more than 9 months. It did not help at all with the vaginal dryness. We even tried it along with a natural product. Still have the dryness. But I do take anti depressants, which I think is the reason these haven't helped me. I 'Il continue trying different alternatives. I wish I could be a guinea pig to help someone come up with something that works for me ."

1 / 10
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3 Report
  • Calgirl
  • Taken for 2 to 5 years
  • January 20, 2023

For Vaginal Dryness "I have been taking this for 3+ years, hoping to experience less painful intercourse. I cannot detect any benefits of taking Osphena, and after reading reviews, I am wondering if my severe hot flashes/night sweats, leg cramps, fatigue, and weight gain are related. I'm stopping this drug today. It may not be causing all of the above symptoms, but it certainly isn't providing any detectable benefits. I'm done."

1 / 10
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0 Report
  • Sue...
  • August 28, 2016

For Dyspareunia "I have experienced a 90% reduction in both vaginal bleeding and painful intercourse. This medication is miraculous. I enjoy sex again!"

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26 Report
  • Dolcet
  • Taken for less than 1 month
  • September 5, 2016

For Dyspareunia "Horrible hot flashes and depression."

1 / 10
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22 Report
  • Nana
  • Taken for 1 to 6 months
  • January 2, 2020

For Vaginal Dryness "Really helped with vaginal dryness and improved my sex life immensely. The only side effect is weight gain of about 7 pounds"

8 / 10
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13 Report
  • LLP
  • Taken for 1 to 6 months
  • April 14, 2019

For Dyspareunia "I have taken this for 3 months and still have very painful sex, feel like a hot poker. I am discontinuing."

3 / 10
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14 Report
  • Piaaz
  • Taken for less than 1 month
  • June 14, 2018

For Dyspareunia "I have gained 5 kgs. I am quitting this. I feel bloated."

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15 Report
  • Meano
  • Taken for 1 to 6 months
  • April 23, 2019

For Dyspareunia "Wish I had started Osphena years ago. Works amazingly."

10 / 10
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12 Report
  • Labry...
  • May 2, 2019

For Perimenopausal Symptoms "I started osphena to maybe help with worsening prolapse...along with pelvic PT. Then 1.5 years later I have had a hysterectomy due to endometrial cancer, also I have had night sweats and hot flashes"

2 / 10
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8 Report
  • Miata...
  • Taken for 1 to 6 months
  • June 16, 2020

For Atrophic Vaginitis "I used this for only two months, had horrible bloating & leg cramps. I stopped. It DID help a tremendous amount with the dryness BUT the cramps just weren't worth it. They were several times a day!"

2 / 10
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6 Report
  • DDano
  • Taken for less than 1 month
  • August 6, 2020

For Atrophic Vaginitis "The side effects from Osphena are not worth the minor results. Overwhelming bloating and cramps."

2 / 10
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2 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 3, 2021

For Atrophic Vaginitis "Making hot flashes unbearable, coming too often land stronger. Is helping with dryness and painful intercourse."

6 / 10
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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.