Midodrine for Postural Orthostatic Tachycardia Syndrome User Reviews

• Ben
• Taken for 1 to 6 months
• October 22, 2022

"Again, unfortunately not all drugs work well in some. I am 91 years old and was put on midodrine x 3 daily for hypotension (the doctors have only realised I have an underactive thyroid) side effects of midodrine were; dizziness and falling over (broke my back and knee, was told it was age related) severe anxiety and confusion (was told I have the beginning of dementia) couldn't talk to breathlessness (was told I have heart failure and COPD ( never smoked or drank) and had a heart scan and xray 1 month before starting midodrine, no heart problems, burning all over, insomnia (walking around the house in the middle of the night confused), cramps all over my body (was told I have osteoarthritis), lack of appetite (was told it was age related). It a shame doctors etc don't want know or help when you reach a certain age and just tell me I have heart problems, dementia, osteoarthritis. My grandson stopped the midodrine and within two days ALL the above symptoms magically disappeared."

• HS004
• August 13, 2014

Orvaten (midodrine) "I take 10mg midodrine three times a day for Postural Orthostatic Tachycardia Syndrome. It has changed my life completely. I'm able to be active and do all the things I used to avoid. I go to concerts, movies on opening night, and shopping at places with long lines. I can date without worrying about whether we're going somewhere that I'll need to stand still. There are side effects - weird sensations and goosebumps mostly. The benefit far outweighs any negative effects or risks."

• toget...
• October 3, 2015

ProAmatine (midodrine) "I have been diagnosed with Dysautonomia & Postural Orthostatic Tachacardia Syndrome and many other things but this medicine was my only option I can't take beta blockers because I need to be able to use my epi-pen and I had a bad reaction to florinef so we decided to try midodrine. It is a lifesavor! I can't go anywhere or do much of anything if I don't take it. I will pass out if I'm not on this medicine, I'm very pleased! I do have to deal with flushing and frequent headaches but it's very much worth it the cost."

• Ddomi...
• August 17, 2010

ProAmatine (midodrine) "ProAmatine is the best thing since sliced bread! Without ProAmatine POTS patients like me would not be able to function! The side effects are minimal and short lasting (they usually go away within the first week) and it gives people their lives back!"

• POTSa...
• August 17, 2011

"Midodrine does not affect postural orthostatic tachycardia syndrome, you need a beta-blocker for that (I am on Propranolol) which keeps your heart from kickstarting the fainting reflex that POTS patients are very susceptible to. Midodrine saved my life, it allows me to literally get up off the floor and get on with life. I have been on it for 10 years, it has a very short life span so I take both medicines every 3 hours. I am able to function quite well, not super-duper, but I can do most things. If it ever is pulled off the market I will literally be going to another country."

• Life...
• Taken for 6 months to 1 year
• February 17, 2023

"Midodrine gave me my life back when I was ready to give up. I'm a 33-year-old woman and take 5mg three times per day and now I can think clearly, stand up without having to brace myself to prevent fainting, I can stand through 95% of my showers now (was sitting most of the time before), I can walk (even up stairs) at a normal pace without getting completely out of breath, my chronic fatigue and brain fog hav dramatically improved, I don't feel the blood draining out of my arms when I lift them above my heart or feel blood pooling in my feet anymore, even my hair started growing again and my acne has improved. This has literally been life changing for me! My body feels a level of peace I've never experienced before. I never got any of the negative side effects others talk about like goosebumps or tingles. However, the first 3 days on this I felt really weird and almost quit but glad I pushed past that and adjusted. I will never be without Midodrine again. It makes life worth living."

• POTSg...
• October 1, 2010

ProAmatine (midodrine) "Didn't seem to lower my heart rate very much, except when I tried to walk around in physical therapy class. Then it caused a severe drop in my heart rate, from about 95 in the relaxed sitting position, to below the 50s when I walked a few yards. Bradycardia is a documented side effect, and unfortunately one I suffered from. Also had lots of goosebumps, tingling scalp, chills and flushing throughout the day. I'm not totally knocking it, because I know it works for some POTS patients, but it wasn't the medicine for me."

• MarkS
• February 1, 2012

"Goosebumps on arms, legs, chest and back; scalp tingling. Reduced my POTS episodes to one or two a month. Wish it were a once-a-day pill instead of every four hours. I take it early morning, lunch and late afternoon."

• Anonymous
• Taken for less than 1 month
• January 4, 2021

"My 19 year old with COVID-induced POTS tried taking midodrine and the side affects were not tolerable. One issue is she was freezing cold with goose bumps all over and they were painful like a stinging feeling. She only took it for a week and then we stopped it."

• canel...
• June 22, 2017

"I get seizures with allergic reactions from Mast cell activation syndrome (MCAS), but I didn't when I first took this drug in 2016. Lots of goosebumps, tingling, tight scalp, chills, shivering, and felt like a zombie, though. Became a different person- dissociated, honestly. That'd never happened to me before, was so afraid. Doctor made me try again, seized the entire time and the tingling burned so bad it felt like I was on fire. Got bradycardic within 2 hours of taking it, too. I get brady sometimes as it is (my heart rate was at 30 the other day) so this medication wasn't a good idea in the first place. Bad call on my doctor's part and bad call on mine for even listening to him."

• 18...
• Taken for 1 to 6 months
• August 30, 2021

"I love it!! Only positive effects for me. Helps my anxiety, and dizziness/spotty vision. Also helps with my energy levels too!! So helpful!! 10/10 only thing is how often I have to take it :( every 4 hours"

• potsy...
• July 21, 2014

ProAmatine (midodrine) "Has definitely helped along with the Digoxin I take to keep me from feeling faint or dizzy. Has improved my quality of life quite a bit. The side effects (for me) are not bad enough to make me stop taking it."

• Anony...
• March 22, 2023

"I was on 10 mg midodrine for years for my P.O.T.S. I’ve had this condition for 17 yrs and am now 70. When I started taking this script it cost me $ 450.00 a month!!! It was extremely hard to come up with that cash but was the only thing that worked. (I also take 5mg of nadolol) I take 10 mg every 4 hours in the daytime and sleep in a head-elevated bed. My blood pressure rose too high last year and my doctor took me off of it. Was a struggle. I am back on it now because had an infection and every time I get sick POTS returns with a vengeance. I do feel the itchy and tingly scalp but that goes away as time goes on. My cost is very reasonable now that I’m on Medicare. I can put up more with this med but still can’t drive because I feel like everything is shutting down and I can’t concentrate on the road. I never want to be without this medication. It doesn’t make me as strong on my feet as healthy people my age but at least it is a good crutch for a more normal life."

• Rocki...
• Taken for 2 to 5 years
• July 20, 2020

"I was doing well on Midodrine for my POTS but also take propranolol and fludricortisone for it. After a few years my blood pressure got too high and my doctor had me stop the midodrine. My POTS is now running my life. I can't even walk around the house without being extremely dizzy."

• Ln2022
• Taken for 1 to 6 months
• October 16, 2020

"Not the drug for me personally. Suffered with POTS for 10+ years now starting new medicines for it. I was prescribed 10mg Midodrine to start. No improvement of POTS symptoms and was on it for about a month. No negative symptoms other than goosebumps at first but after about a month on it my blood pressure started shooting up and I felt super sick from it. I had high hopes because it helps so many people but it just wasn't for me."

• kckcg...
• Taken for 1 to 6 months
• July 19, 2021

"This drug,midodrine, is so short acting, there is a small window of time that it helps. Am now on 10mg tid which is about the max dose. Have added fludrocortisone 0.1 bid to support BP and increased salt intake considerably. The salt really helps, biggest quickest way to increase salt intake is soy sauce ! Propranalol 5mg bid, a tiny tiny dose, takes care of tachycardia."

• Anonymous
• Taken for less than 1 month
• April 20, 2016

"Really bad reaction with me.severe side effects with little to no results."

• simpl...
• December 20, 2009

ProAmatine (midodrine) "Rash, goosebumps even when hot, odd blood pressure swings, scalp tingling and other problems. Was taken off it fairly quickly."