Skip to main content

Unithroid User Reviews & Ratings

Unithroid has an average rating of 5.5 out of 10 from a total of 14 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 54% reported a negative experience.

Condition Avg. Rating Reviews Compare
Hashimoto's disease  
7.5
 5 reviews for Hashimoto's disease 29 medications
Hypothyroidism, After Thyroid Removal  
3.2
 6 reviews for Hypothyroidism, After Thyroid Removal 29 medications
Underactive Thyroid  
7.3
 3 reviews for Underactive Thyroid 38 medications
Add your review

Reviews for Unithroid

  • Ziten...
  • July 24, 2019

For Hypothyroidism, After Thyroid Removal "I received a prescription of Unithroid 75MG/BID after having major problems with Nature Throid. DR said that this medicine is better for people with IBS and other GI problems who've had problems taking other synthetic T4 mediation. This medicine supposedly contained very few ingredients and dyes. I was skeptical but started it. After only taking medicine for 2 days, my stomach made loud noises and shook and churned like a washing machine. Adverse reaction started quickly & intensity increased fast with this supposedly gentle medicine. This medicine is no milder or easier on your stomach than the other preparation. Unithroid contains lactose and dyes in every strength but the 50 mg tablets. I haven't had my labs yet to see if absorption is also an issue but even if it absorbs well, if it cause GI distress, what good is it?"

3 / 10
Was this helpful?YesNo
30 Report
  • otaku...
  • Taken for less than 1 month
  • August 29, 2018

For Underactive Thyroid "I was on generic Levothyroxine for just about under a year or so. At first it was ok. Then when I recently went to get my refill the pills had a very strong odor. It's hard to describe. Like a strange mix between a chemical smell and dirty feet. Makes you want to gag when taking them. I learned about Unithroid from a family member and asked my doctor to change me to Unithroid. It is really reasonable ($) like the generic but Unithroid has no nasty smell. I also just found out that it is made in the USA so that's cool. I am happy about switching over."

10 / 10
Was this helpful?YesNo
30 Report
  • Syd
  • Taken for less than 1 month
  • September 9, 2022

For Underactive Thyroid "Post partial thyroidectomy due to a large benign nodule. Started on 50mcg of Unithroid. First few days were fine, took only 6 doses. Started having severe anxiety, restlessness, high blood pressure, high heart rate. Started at a TSH of 4.1, with 6 days of taking medicine TSH dropped to 2.4. Will not take any more! Feeling like I was over medicated."

2 / 10
Was this helpful?YesNo
11 Report

Frequently asked questions

  • Kkano
  • Taken for 1 to 2 years
  • March 31, 2021

For Hashimoto's disease "After 6 thyroid specialists, 3 hospital admissions, a gammet of various T4 meds at dosages ranging from 25mcg-125mcg and allergic reactions and increasing debilitating hypo symptoms. Unithroid is the med that FINALLY started bringing this nightmare under control. 50mcg + 5mcg compounded clean T3 3xday."

10 / 10
Was this helpful?YesNo
15 Report
  • kingk...
  • Taken for 10 years or more
  • December 28, 2019

For Hashimoto's disease "When the medication was made by Johnson-Stevens, it worked very well. I’ve been on it for over 10 years. The past couple years, something changed and it stopped working. After taking it in the morning, I had a metallic taste in my mouth and made me very tired. I will report these side effects to the FDA. Had to switch to another brand made in Austria, but works very well."

1 / 10
Was this helpful?YesNo
18 Report

Are you taking this medicine?

  • Kelly
  • Taken for less than 1 month
  • July 4, 2023

For Hashimoto's disease "I have been on Unithroid for a few weeks. I was diagnosed with Hashimoto's when I was 13, and now at 55, I was on Synthroid for 35+ years. I always felt horrible - irritated, had sleep issues, and couldn't focus on anything. In the few weeks I've changed meds, I feel like a new person! I wish I had asked for other options years ago! I also had gained 25+ lbs, and now I'm losing weight and hoping to be back to where I was years ago."

9 / 10
Was this helpful?YesNo
5 Report
  • Redhead
  • Taken for 1 to 6 months
  • February 16, 2020

For Hypothyroidism, After Thyroid Removal "I started on levothyroxine after my thyroidectomy due to cancer after about 7 months I decided to switch to brand name and my doctor picked this. While my body adjusted to the new stuff I felt awful. I had a couple days I felt really good and then boom it all went down hill. My period was four days early and horrible. I also became extremely anxious and depressed. This med is not right for me and I am hopeful to get to switch and try something new. If I have to be on it for life, better make sure it suits my body."

3 / 10
Was this helpful?YesNo
17 Report

More FAQ

  • jrb
  • Taken for less than 1 month
  • October 26, 2020

For Hypothyroidism, After Thyroid Removal "I had a partial thyroidectomy. I took generics for years and the Sandoz distributed generic made by Cediprof disappeared after a distributing war. I needed a brand so this won't happen again. I felt terrible on Unthroid from the moment I took it in the morning, with nausea, finger pain and overall ill feeling. I didn't take it the next day and the symptoms went away. My Dr recommended Levoxyl and all those symptoms went away and it's cheaper. Unithroid puts a bunch of rubbish in their meds and clearly it does make a difference."

1 / 10
Was this helpful?YesNo
12 Report
  • Nadia...
  • February 6, 2016

For Hypothyroidism, After Thyroid Removal "I get sick, angry and depressed from the medicine. I get migraines, I can't take it but through my research I am going to ask for Armour , it is natural but it replaces two hormones and you do need a prescription"

1 / 10
Was this helpful?YesNo
19 Report
  • MCL
  • Taken for 6 months to 1 year
  • September 15, 2021

For Hashimoto's disease "I was seeing an endocrinologist that prescribed armor thyroid. She worked with me to keep my TSH at a 1.0. She retired and started seeing another endocrinologist. He put me on Unithroid and I felt awful on it. I was constipated, bloated, carpals tunnel in my hands, and major brain fog. I convinced my Primary care to prescribe armor for me and I feel so much better."

Was this helpful?YesNo
8 Report
  • Tom
  • Taken for 10 years or more
  • August 26, 2016

For Hypothyroidism, After Thyroid Removal "My thyroid was removed in 1978 due to cancer. I started out on Armour but was eventually switched over to Synthroid. I have had no side effects from the drug and my doctor and I have been happy with the results. Frequent blood monitoring dictated that I alternate between 175mcg and 150mcg doses per day in order to fine tune my "numbers.""

9 / 10
Was this helpful?YesNo
16 Report
  • Tabby...
  • January 20, 2018

For Hypothyroidism, After Thyroid Removal "This medication gave me severe gastric upset. And it messed up my levels so bad. I was on Sandoz brand for years and got switched to this. All of a sudden I'm severely overdosed. This med does absorb better then most so doctors beware."

2 / 10
Was this helpful?YesNo
12 Report
  • Saman...
  • Taken for 10 years or more
  • December 1, 2020

For Underactive Thyroid "Unithroid is first FDA approved thyroid meds. I noticed when my mother took this over synthroid she was more alert. I have been on it 20 years. No problem."

10 / 10
Was this helpful?YesNo
20 Report
  • Shafett
  • September 20, 2016

For Hashimoto's disease "I take it in the morning and with the help of my Dr. my numbers have been stable."

10 / 10
Was this helpful?YesNo
15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.