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Synthroid User Reviews & Ratings (Page 5)

Synthroid has an average rating of 6.1 out of 10 from a total of 192 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Synthroid

  • xdoll
  • Taken for 10 years or more
  • January 16, 2022

For Underactive Thyroid "I’ve been on this medication since I was 7, and I am now 32. Never had any issues that I can relate back to synthroid. But I’m curious if my anxiety and panic disorder is related to this, because I have had it since around the same time I started this med and suffered my whole life. I also recently started having chronic dizziness that is pretty much 24/7 for the last 5 years. It’s probably not related but I’m curious if anyone else feels the same."

10 / 10
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  • Batty
  • January 3, 2018

For Underactive Thyroid "Thyroidectomy after cancer diagnosis and so far I've had not had great luck with synthyroid. Currently I'm on 112 mcg and it makes me feel like I have a itchy sunburn and the weight gain is insane I feel water logged in my legs most of the time and too many mental glitches. I dislike this drug it's has to many fillers that cause other issues. If you have a known allergies avoid synthyroid until they can create an allergy free version."

7 / 10
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  • Anonymous
  • June 24, 2010

For Underactive Thyroid "I have been taking this for 6 months now. Before these medicines I had problems gaining weight. Now that I am on this medicine, I can't stop eating. I have gained 20 lbs. When I stop taking these medicines I am not hungry all the time. I also have high blood pressure. Not sure if the combination of the medicines has anything with to do with the weight gain."

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Frequently asked questions

  • Anonymous
  • January 30, 2009

For Hashimoto's disease "I have been on Synthroid and the generic for eleven years. If you ever suffered from the effects of thyroid disease you probably know the depression and fatigue that I felt 11 years ago. I only noticed two side effects. One was an interaction with birth control, the other was my hair wouldn't perm well anymore (small price to pay)."

7 / 10
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58 Report
  • Anonymous
  • May 30, 2011

For Underactive Thyroid "I have been taking Synthroid for almost two years. My doctor told me that I might not be able to conceive but I am 15 weeks pregnant. My current doctor told me to take this medicine religiously because this is keeping me pregnant. "

10 / 10
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51 Report

Are you taking this medicine?

  • Patri...
  • August 28, 2017

For Hashimoto's disease "43 years old female, 5'7", 76 kg. I used to be 56 kg , and in a matter of 2 years I reached 80 kg after quitting smoking. I also had a plethora of other problems, amount which lethargy, extreme fatigue , depression . My doc discovered by accident my TSH was 10 , plus huge antibodies values. Started me at 50 mag Syntroid and I went up from there. I am now at 175 mcg , huge dose, and feel fantastic. My blood values are low,TSH , upper limit T4. I kind of talked my doc in increasing the dose.... as his choice was 125 mcg and I felt that was too low . I finally have the energy to go to the gym . I feel like my old self. I LOVE Syntroid and I hope he won't lower it for me ."

10 / 10
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  • JakeB...
  • April 27, 2017

For Hypothyroidism, After Thyroid Removal "After my thyroid surgery, I was put on Synthroid. I continued to get WORSE until I was nearly totally bedridden. I did some research and after several months, found a doctor who prescribed medications other than synthroid. I started taking a Natural desiccated thyroid (NDT) medicine. Within two weeks, I woke up and felt like getting out of bed. I continued to improve, however my strength never came back. I am totally confined to a wheelchair now."

1 / 10
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More FAQ

  • dvdbr...
  • July 19, 2016

For Underactive Thyroid "I'm hypothyroid and skinny as a rail and cannot even gain a single pound, 58 yo, 5'6" 88 lbs, thyroid damaged through radiation, have been on synthroid/levothyroxin 50 mcg daily, and I notice no change at all, still no energy, still totally exhaust 24/7,still losing weight like crazy with a relatively healthy appetite. However, since I totally trust my oncologist, I keep taking them."

1 / 10
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  • Not-H...
  • July 20, 2021

For Hypothyroidism, After Thyroid Removal "I had a thyroidectomy and I'm on synthroid. This medicine just doesn't work like they told me it would. It doesn't work!!!! My nails are falling off and ripping more easily. My hair which was always so beautiful and long is looking like a dollar store mop. It has breakage really bad and it's so thin and just yucky. Also gained 70 pounds"

2 / 10
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  • Dele
  • August 16, 2016

For Hypothyroidism, After Thyroid Removal "Thyroid was removed 3 years ago due to hashimoto and nodule hyperplasia. Surgery discovered a substernal thyroid. Prior to surgery and attempts to reduce goiter with synthroid, felt terrible everyday. Multiple diagnosis due to muscle pain,fatigue, insonima, stomach upset, rapid heart beat, irrational blood pressure. Take synthroid every morning 1 hour prior to breakfast. Feel great. No negative side effects. All above symptoms are gone. Age 59!"

10 / 10
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  • Anonymous
  • May 20, 2010

For Underactive Thyroid "OK im still on Sythyroid and my doctor will not listen to me.He told me to see an ob/gyn and they made me an appointment but i have to wait another two weeks and my menstruation has gone crazy. Ive been bleeding since April 15 i stopped for 2 days and it started again. all my tests say im normal. i went to the er and they told me everything was fine! im so frustrated with this. No one will listen to me!! It takes 4-6 weeks to kick in i started this medicine in November ive had my dosage changed 3 times. this last time i went from .75 to .88 and exactly 6 weeks and one day my menstruation started early i thought that was just a slight bump but now its out of control! I know my own body i know it this medicine. im sensitive to medications"

2 / 10
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  • Cory
  • Taken for 1 to 6 months
  • October 29, 2020

For Hashimoto's disease "Started Synthroid 50 mcgs on August 25th 2020. I was 6’3 at 266 lbs. It is now October 28th 2020 and I have lost 49 pounds. My weight is 217lb. If you have hashimotos disease. I highly recommend the paleo or AIP diet. All I did was diet and take my meds every day at 9 a.m on an empty stomach with water. I would then wait till 12 before I would eat lunch to make sure all of the meds absorbed. My antibody count is still unreadable so I have to up my dose to 75 mcgs now. Needless to say this medicine seems to do it’s job. But your diet is nearly as important."

9 / 10
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  • Vinoj...
  • Taken for 1 to 6 months
  • June 6, 2016

For Hypothyroidism, After Thyroid Removal "I had my thyroid out in Feb. of 2016. I was put on 125mgr of generic Synthroid. My blood sugar was dropping below 50 on a daily basis. I looked the problem up on the internet and found that people had the same problem and advocated that I take the brand name drug to correct the problem. For the past two months I have been on the name brand and I seem to be leveling out in the high 60s with my sugar which is ok. I am stuck paying the extra charge not covered by my insurance. roughly $32 per month for 30 pills. Have had no weight gain yet which I am very happy about. I am going to ask my doctor at the end of this month to increase my dosage to bring my sugar up into the 80s or even 90s where it belongs."

6 / 10
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  • Borega
  • June 20, 2015

For Hypothyroidism, After Thyroid Removal "I was taking Levothyroid 75mcg. Lost 15 pounds, stomach pain, unable to eat, shaky, unable to think or exercise. Also have dark, stone hard stools. Will see my endocrinologist next week. When in my 30's, took Synthyroid for 16 years with no problems, then all went as above. Took Levothyroid by Forest for 4 years with no problems until it was taken of the market about 2 years ago."

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  • Jujub...
  • Taken for 2 to 5 years
  • October 27, 2017

For Underactive Thyroid "I've been on both and yes you have to see a Dr. who specializes in this disorder and you also have to take it one hour before you eat both levo and synthroid because I feel different I've done it taking after I ate and didn't work and then I followed the doctors orders take one hour before breakfast. I'm on 75mcg and my weight is doing great my levels normal if I keep on the medicine and take it like my doctor said to take it and I go to many different specialist's because I have many medical problems and I'm only 30 but this thyroid be thing started after I had my daughter so no do not take it at night after meals cuz your body will not absorb the medicine correct the medicine needs to be with a full glass of water and no food so it can work thru"

10 / 10
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  • angel...
  • March 9, 2010

For Hashimoto's disease "I have been on Synthroid for a while and when I started having stomach issues I could no longer tolerate pills. My endo doc changed me from Synthroid to Levoxyl and I couldn't tolerate that either. Now I'm on injectable, what a relief to know I have options!"

9 / 10
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  • Bette...
  • May 19, 2009

For Hypothyroidism, After Thyroid Removal "I have had my thyroid removed one year ago. Medication causes blurred vision. Some weight gain nothing significant that can't be worked off with exercise. But, even though I have this problem, it's better than previous symptoms, heart palpitations, sweating, losing 20lbs in less than a month without trying."

5 / 10
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44 Report
  • Early...
  • August 7, 2011

For Hypothyroidism, After Thyroid Removal "Synthroid seems to work well, but still working to get to the correct dosage. Currently, my dose is too high and I see my doctor next week to adjust. Feel fine, but have daily armpit and back sweat. Will be really glad when that stops as it's difficult to work at client sites when your shirt is soaked."

8 / 10
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  • works...
  • Taken for 10 years or more
  • September 19, 2023

For Underactive Thyroid "I have my hair, eyebrows, and lashes. I retain water. I feel tired often, but I sleep fine. Mood is stable. Weight is about 10 lbs over where I'd like to be, but not bad. Without this medication, I would feel way worse. I've been on it for 20 years. It's not perfect, but I can't live without it."

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  • NoSle...
  • Taken for 1 to 2 years
  • July 12, 2021

For Underactive Thyroid "I've been on levothyroxine for a year now and my life is so much better. When I graduated college at 21 and started working full-time, I was suddenly tired. All the time. Basic tasks made me exhausted. I always thought it was depression and tried counseling for years. I finally went to the doctor when I was 25 to get antidepressants and she made me get bloodwork done. I had an atrophied thyroid! After about six weeks on levo, I had so much energy and even lost 10 pounds! Then it stopped working, so we had to adjust the dosage. I haven't had any long-term weight loss unfortunately, but my energy is back up and I wake up refreshed, which is exactly what I needed."

10 / 10
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  • Just...
  • Taken for less than 1 month
  • May 1, 2015

For Underactive Thyroid "I had a blood test 3 weeks ago and I knew something was wrong. The doctor prescribed this to me. I don't know my numbers. I'm taking 25 mcg. I was tired before but now I feel like I'm dead. Too bad you can't take this medicine at night. I never had a puffy face, but the cold bothered me a little . Very dry skin that developed over the winter. I used to have Addison's Disease, which was easier to check with a simple prick of the finger."

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  • angela...
  • August 16, 2016

For Hypothyroidism, After Thyroid Removal "Had my thyroid removed at age 9 (cancer) 38 yrs ago. Been on Synthroid ever since then. My dosage has changed over the years. I am now on 150 mg (blue tablets) I have been getting a all over skin rash and itching for the last 4 months. After numerous tests my doctor told me it may be the dye in the blue 150 mg tablets. Has anyone else experienced this problem? I just switched today to take the 50 mg (white tablets with no dye) three times a day. I am hoping this was the problem."

8 / 10
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  • Patient
  • Taken for 10 years or more
  • January 18, 2024

For Hashimoto's disease "I've taken name brand Synthroid for 30 years now. At first, when I was on the lower dosages, the 25 and 50 mcg, it seemed to work fine. Then suddenly, my TSH went up and I was referred to a new endocrine doctor, and we raised my dosage to 75 mcg. This caused palpitations and severe anxiety, so we went down to 62.5 mcg (125 mcg cut in half). I've been on 62.5 for a while now, and I'm frustrated. After my dosage kept going up, I've gained 10 lbs over a few weeks. I've also developed a constantly bloated abdomen and face, heartburn, constant hunger which I manage by staying on 1200 calories a day and no snacking. I also work out daily. I've been tested for H. Pylori, SIBO, celiac, food intolerances, etc. and no answers. I think this medication causes all of these issues at higher dosages. My current TSH is 1.4, but I am going to see if I can try something else or try alternating with a lower dosage. I'm tired of waking up to my clothes not fitting and constantly looking pregnant."

5 / 10
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  • firep...
  • Taken for 2 to 5 years
  • October 2, 2016

For Hypothyroidism, After Thyroid Removal "I was 1st diagnosed w/hyperparathyroidism.The dr. said it wasn't bad to just watch it.After a couple of years it got worse-I saw another dr. & he did 6 biopsy's-found that I had Papillary Cancer-following mo. I had my thyroid & 2 parathyroids removed-surgeon put me on 100mcg of generic Synthroid-seemed to be doing ok until I had the RAI, twice, then everything messed up. I was still having hair loss, ears ringing, teeth getting bad, bathroom habits were never the same, cramps, affected my salivary glands permanently so I'm dry all the time plus I've put on 25 lbs. I eat, I don't eat, it doesn't matter, the weight will not come off.The Endo dr. changed my dosage to 112mcg & I seemed to be doing better.I am back to 100mcg w/previous symptoms."

7 / 10
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  • Lovely...
  • May 15, 2011

For Myxedema Coma "I'm 54 yo, and have had Graves Disease since I was 21, after the birth of my first child. At that time 9/10 of my thyroid was removed due to a nodular goiter. For about 20 years, I was fine without any medication. About 15 years ago, I began Synthroid at 25 mcg and am now up to 75mcg. I feel well. However, I am extremely careful about my health in general - take many supplements, and no other drugs, and eat a very healthy diet. I did HRT for about 10 years, and stopped this year. Still, feeling fine. I'm sure my diet and lifestyle have a lot to do with that. I think you should get second and third opinions from endocrinologists if your concerns aren't being taken seriously by your GP."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.